Publications
Xu J, Gong NL, Bodi I, Aronow BJ, Backx PH, Molkentin JD. Myocyte enhancer factors 2A and 2C induce dilated cardiomyopathy in transgenic mice. The Journal of biological chemistry. 2006 Apr 7;281(14):9152-62.
Barnes M, Freudenberg J, Thompson S, Aronow BJ, Pavlidis P. Experimental comparison and cross-validation of the Affymetrix and Illumina gene expression analysis platforms. Nucleic Acids Res. 2005;33(18):5914-23.
Kong S, Aronow BJ, Handwerger S. Gene expression microarray data analysis of decidual and placental cell differentiation. Methods Mol Med. 2006;121:425-38.
Oka T, Maillet M, Watt AJ, Schwartz RJ, Aronow BJ, Duncan SA, Molkentin JD. Cardiac-specific deletion of Gata4 reveals its requirement for hypertrophy, compensation, and myocyte viability. Circ Res. 2006 Mar 31;98(6):837-45.
Carvalho E, Liu C, Shivakumar P, Sabla G, Aronow BJ, Bezerra JA. Analysis of the biliary transcriptome in experimental biliary atresia. Gastroenterology. 2005 Aug;129(2):713-7.
Blanchard C, Wang N, Stringer KF, Mishra A, Fulkerson PC, Abonia JP, Jameson SC, Kirby C, Konikoff MR, Collins MH, Cohen MB, Akers R, Hogan SP, Assa'ad AH, Putnam PE, Aronow BJ, Rothenberg ME. Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis. The Journal of clinical investigation. 2006 Feb;116(2):536-47.
Robins JC, Akeno N, Mukherjee A, Dalal RR, Aronow BJ, Koopman P, Clemens TL. Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9. Bone. 2005 Sep;37(3):313-22.
Mallakin A, Kutcher LW, McDowell SA, Kong S, Schuster R, Lentsch AB, Aronow BJ, Leikauf GD, Waltz SE. Gene expression profiles of Mst1r-deficient mice during nickel-induced acute lung injury. Am J Respir Cell Mol Biol. 2006 Jan;34(1):15-27.
Lowy AM, Clements WM, Bishop J, Kong L, Bonney T, Sisco K, Aronow BJ, Fenoglio-Preiser C, Groden J. Beta-Catenin/Wnt signaling regulates expression of the membrane type 3 matrix metalloproteinase in gastric cancer. Cancer Res. 2006 May 1;66(9):4734-41.
Miller SJ, Rangwala F, Williams J, Ackerman P, Kong S, Jegga AG, Kaiser S, Aronow BJ, Frahm S, Kluwe L, Mautner V, Upadhyaya M, Muir D, Wallace M, Hagen J, Quelle DE, Watson MA, Perry A, Gutmann DH, Ratner N. Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues. Cancer Res. 2006 Mar 1;66(5):2584-91.
Jegga AG, Gupta A, Gowrisankar S, Deshmukh MA, Connolly S, Finley K, Aronow BJ. CisMols Analyzer: identification of compositionally similar cis-element clusters in ortholog conserved regions of coordinately expressed genes. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W408-11.
Smiley AK, Klingenberg JM, Aronow BJ, Boyce ST, Kitzmiller WJ, Supp DM. Microarray analysis of gene expression in cultured skin substitutes compared with native human skin. J Invest Dermatol. 2005 Dec;125(6):1286-301.
Beis D, Bartman T, Jin SW, Scott IC, D'Amico LA, Ober EA, Verkade H, Frantsve J, Field HA, Wehman A, Baier H, Tallafuss A, Bally-Cuif L, Chen JN, Stainier DY, Jungblut B. Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development. Development (Cambridge, England). 2005 Sep;132(18):4193-204.
Mikhalkevich N, Becknell B, Caligiuri MA, Bates MD, Harvey R, Zheng W. Responsiveness of NaÏve CD4 T Cells to Polarizing Cytokine Determines the Ratio of Th1 and Th2 Cell Differentiation. Journal Of Immunology. 2006 Feb;176:1553-60.
Erwin CR, Jarboe MD, Sartor MA, Medvedovic M, Stringer KF, Warner BW, Bates MD. Developmental characteristics of adapting mouse small intestine crypt cells. Gastroenterology. 2006 Apr;130(4):1324-32.
Lee HY, Wroblewski E, Philips GT, Stair CN, Conley K, Reedy M, Mastick GS, Brown NL. Multiple requirements for Hes 1 during early eye formation. Developmental biology. 2005 Aug 15;284(2):464-78.
Waclaw RR, Allen ZJ, 2nd, Bell SM, Erdelyi F, Szabo G, Potter SS, Campbell K. The zinc finger transcription factor Sp8 regulates the generation and diversity of olfactory bulb interneurons. Neuron. 2006 Feb 16;49(4):503-16.
Degen JL, Massari JV, Talmage KE, La Jeunesse CM, Kombrinck KW, Flick MJ, Palumbo PS. Hemostatic factors support metastasis by impeding NK cell-mediated elimination of embolic tumor cells. Haematological Reports 2005. 2005 October;1(9):21-3.
Shanmukhappa K, Mourya R, Sabla GE, Degen JL, Bezerra JA. Hepatic to pancreatic switch defines a role for hemostatic factors in cellular plasticity in mice. Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10182-7.
Cho J, Degen JL, Coller BS, Mosher DF. Fibrin but Not Adsorbed Fibrinogen Supports Fibronectin Assembly by Spread Platelets: Effects of the Interaction of Alpha IIbeta3 with the C Terminus of the Fibrinogen-Chai. Journal of Biological Chemistry. 2005 October 21;280(42):35490-98.
Kahn JA, Degen SJ, Mansour ME, Goodman E, Zeller MH, Laor T, Lanphear NE, Boat TF. Pediatric faculty members' attitudes about part-time faculty positions and policies to support part-time faculty: a study at one medical center. Acad Med. 2005 Oct;80(10):931-9.
Devarajan P. Update on mechanisms of ischemic acute kidney injury. J Am Soc Nephrol. 2006 Jun;17(6):1503-20.
Mishra J, Ma Q, Kelly C, Mitsnefes M, Mori K, Barasch J, Devarajan P. Kidney NGAL is a novel early marker of acute injury following transplantation. Pediatr Nephrol. 2006 Jun;21(6):856-63.
Mitsnefes M, Kimbal T, Kartal J, Kathman T, Mishra J, Devarajan P. Serum cystatin C and left ventricular diastolic dysfunction in children with chronic kidney disease. Pediatr Nephrol. 2006 May 24.
Schmidt-Ott KM, Mori K, Kalandadze A, Li JY, Paragas N, Nicholas T, Devarajan P, Barasch J. Neutrophil gelatinase-associated lipocalin-mediated iron traffic in kidney epithelia. Curr Opin Nephrol Hypertens. 2006 Jul;15(4):442-9.
Eichler T, Ma Q, Kelly C, Mishra J, Parikh S, Ransom RF, Devarajan P, Smoyer WE. Single and combination toxic metal exposures induce apoptosis in cultured murine podocytes exclusively via the extrinsic caspase 8 pathway. Toxicol Sci. 2006 Apr;90(2):392-9.
Tarabishi R, Zahedi K, Mishra J, Ma Q, Kelly C, Tehrani K, Devarajan P. Induction of Zf9 in the kidney following early ischemia/reperfusion. Kidney Int. 2005 Oct;68(4):1511-9.
Nguyen MT, Ross GF, Dent CL, Devarajan P. Early prediction of acute renal injury using urinary proteomics. Am J Nephrol. 2005 Jul-Aug;25(4):318-26.
Standley HJ, Destree O, Kofron M, Wylie C, Heasman J. Maternal XTcf1 and XTcf4 have distinct roles in regulating Wnt target genes. Developmental biology. 2006 Jan 15;289(2):318-28.
Heasman J. Maternal determinants of embryonic cell fate. Semin Cell Dev Biol. 2006 Feb;17(1):93-8.
Birsoy B, Kofron M, Schaible K, Wylie C, Heasman J. Vg 1 is an essential signaling molecule in Xenopus development. Development (Cambridge, England). 2006 Jan;133(1):15-20.
Heasman J. Patterning the early Xenopus embryo. Development (Cambridge, England). 2006 Apr;133(7):1205-17.
Liou B, Kazimierczuk A, Zhang M, Scott CR, Hegde RS, Grabowski GA. Analyses of variant acid beta-glucosidases: effects of Gaucher disease mutations. The Journal of biological chemistry. 2006 Feb 17;281(7):4242-53.
Wang L, Yang L, Burns K, Kuan CY, Zheng Y. Cdc42GAP regulates c-Jun N-terminal kinase (JNK)-mediated apoptosis and cell number during mammalian perinatal growth. Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13484-9.
Chu Z, Sun Y, Kuan CY, Grabowski GA, Qi X. Saposin C: neuronal effect and CNS delivery by liposomes. Ann N Y Acad Sci. 2005 Aug;1053:237-46.
Lobov IB, Rao S, Carroll TJ, Vallance JE, Ito M, Ondr JK, Kurup S, Glass DA, Patel MS, Shu W, Morrisey EE, McMahon AP, Karsenty G, Lang RA. WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature. Nature. 2005 Sep 15;437(7057):417-21.
Miller LA, Smith AN, Taketo MM, Lang RA. Optic cup and facial patterning defects in ocular ectoderm beta-catenin gain-of-function mice. BMC Dev Biol. 2006;6:14.
Smith AN, Miller LA, Song N, Taketo MM, Lang RA. The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm. Developmental biology. 2005 Sep 15;285(2):477-89.
Ma J. Transcriptional activators and activation mechanisms. Gene Expression and Regulation. 2006:147-58.
Fu D, Ma J. Interplay between positive and negative activities that influence the role of Bicoid in transcription. Nucleic Acids Res. 2005 July 19;33(13):3985-93.
Baird-Titus JM, Clark-Baldwin K, Dave V, Caperelli CA, Ma J, Rance M. The solution structure of the native K50 Bicoid homeodomain bound to the consensus TAATCC DNA-binding site. J Mol Biol. 2006 Mar 10;356(5):1137-51.
Patten BA, Sardi SP, Koirala S, Nakafuku M, Corfas G. Notch1 signaling regulates radial glia differentiation through multiple transcriptional mechanisms. J Neurosci. 2006 Mar 22;26(12):3102-8.
Kriks S, Lanuza GM, Mizuguchi R, Nakafuku M, Goulding M. Gsh2 is required for the repression of Ngn1 and specification of dorsal interneuron fate in the spinal cord. Development (Cambridge, England). 2005 Jul;132(13):2991-3002.
Schwab K, Hartman HA, Liang HC, Aronow BJ, Patterson LT, Potter SS. Comprehensive microarray analysis of Hoxa11/Hoxd11 mutant kidney development. Developmental biology. 2006 May 15;293(2):540-54.
Brunskill EW, Ehrman LA, Williams MT, Klanke J, Hammer D, Schaefer TL, Sah R, Dorn GW, 2nd, Potter SS, Vorhees CV. Abnormal neurodevelopment, neurosignaling and behaviour in Npas3-deficient mice. Eur J Neurosci. 2005 Sep;22(6):1265-76.
Collins MD, Eckhoff C, Weiss R, Resnick E, Nau H, Scott WJ, Jr. Differential teratogenesis of all-trans-retinoic acid administered on gestational day 9.5 to SWV and C57BL/6N mice: emphasis on limb dysmorphology. Birth Defects Res A Clin Mol Teratol. 2006 Feb;76(2):96-106.
Park KS, Wells JM, Zorn AM, Wert SE, Whitsett JA. Sox17 influences the differentiation of respiratory epithelial cells. Developmental biology. 2006 Jun 1;294(1):192-202.
Dessimoz J, Opoka R, Kordich JJ, Grapin-Botton A, Wells JM. FGF signaling is necessary for establishing gut tube domains along the anterior-posterior axis in vivo. Mech Dev. 2006 Jan;123(1):42-55.
Park KS, Wells JM, Zorn AM, Wert SE, Laubach VE, Fernandez LG, Whitsett JA. Transdifferentiation of ciliated cells during repair of the respiratory epithelium. Am J Respir Cell Mol Biol. 2006 Feb;34(2):151-7.
Akei H, Whitsett JA, Buroker M, Ninomiya T, Tatsumi H, Weaver TE, Ikegami M. Surface Tension Influences Cell Shape and Phagocytosis in Alveolar Macrophages. Am J Physiol Lung Cell Mol Physiol. 2006 Apr 21.
Kingma PS, Whitsett JA. In defense of the lung: surfactant protein A and surfactant protein D. Current opinion in pharmacology. 2006 Jun;6(3):277-83.
Wedig KE, Kogan J, Schorry EK, Whitsett JA. Skeletal demineralization and fractures caused by fetal magnesium toxicity. J Perinatol. 2006 Jun;26(6):371-4.
Whitsett JA. Genetic disorders of surfactant homeostasis. Paediatric respiratory reviews. 2006 June 5;7 Suppl 1:S240-2.
Whitsett JA. Disorders of lung morphogenesis. Paediatric respiratory reviews. 2006;7 Suppl 1:S248.
Matsuzaki Y, Xu Y, Ikegami M, Besnard V, Park KS, Hull WM, Wert SE, Whitsett JA. Stat3 is required for cytoprotection of the respiratory epithelium during adenoviral infection. J Immunol. 2006 Jul 1;177(1):527-37.
Kohl J, Baelder R, Lewkowich IP, Pandey MK, Hawlisch H, Wang L, Best J, Herman NS, Sproles AA, Zwirner J, Whitsett JA, Gerard C, Sfyroera G, Lambris JD, Wills-Karp M. A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma. The Journal of clinical investigation. 2006 Mar;116(3):783-96.
Mucenski ML, Nation JM, Thitoff AR, Besnard V, Xu Y, Wert SE, Harada N, Taketo MM, Stahlman MT, Whitsett JA. Beta-catenin regulates differentiation of respiratory epithelial cells in vivo. Am J Physiol Lung Cell Mol Physiol. 2005 Dec;289(6):L971-9.
Ikegami M, Carter K, Bishop K, Yadav A, Masterjohn E, Brondyk W, Scheule RK, Whitsett JA. Intratracheal recombinant surfactant protein d prevents endotoxin shock in the newborn preterm lamb. American journal of respiratory and critical care medicine. 2006 Jun 15;173(12):1342-7.
Martis PC, Whitsett JA, Xu Y, Perl AK, Wan H, Ikegami M. C/EBPalpha is required for lung maturation at birth. Development (Cambridge, England). 2006 Mar;133(6):1155-64.
Ikegami M, Whitsett JA, Martis PC, Weaver TE. Reversibility of lung inflammation caused by SP-B deficiency. Am J Physiol Lung Cell Mol Physiol. 2005 Dec;289(6):L962-70.
Xu Y, Liu C, Clark JC, Whitsett JA. Functional genomic responses to cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR(delta508) in the lung. The Journal of biological chemistry. 2006 Apr 21;281(16):11279-91.
Whitsett JA. Surfactant proteins in innate host defense of the lung. Biology of the neonate. 2005 Sept. ;88(3):175-80.
Perl AK, Wert SE, Loudy DE, Shan Z, Blair PA, Whitsett JA. Conditional recombination reveals distinct subsets of epithelial cells in trachea, bronchi, and alveoli. Am J Respir Cell Mol Biol. 2005 Nov;33(5):455-62.
Besnard V, Wert SE, Kaestner KH, Whitsett JA. Stage-specific regulation of respiratory epithelial cell differentiation by Foxa1. Am J Physiol Lung Cell Mol Physiol. 2005 Nov;289(5):L750-9.
Ikegami M, Le Cras TD, Hardie WD, Stahlman MT, Whitsett JA, Korfhagen TR. TGF-alpha perturbs surfactant homeostasis in vivo. Am J Physiol Lung Cell Mol Physiol. 2005 Jul;289(1):L34-43.
Maeda Y, Hunter TC, Loudy DE, Dave V, Schreiber V, Whitsett JA. PARP-2 interacts with TTF-1 and regulates expression of surfactant protein-B. The Journal of biological chemistry. 2006 Apr 7;281(14):9600-6.
Whitsett JA, Wert SE, Xu Y. Genetic disorders of surfactant homeostasis. Biology of the neonate. 2005 June 1;87(4):283-7.
Takeuchi Y, Molyneaux K, Runyan C, Schaible K, Wylie C. The roles of FGF signaling in germ cell migration in the mouse. Development (Cambridge, England). 2005 Dec;132(24):5399-409.
Houston DW, Wylie C. Maternal Xenopus Zic2 negatively regulates Nodal-related gene expression during anteroposterior patterning. Development (Cambridge, England). 2005 Nov;132(21):4845-55.
Wylie C. IFITM1-mediated cell repulsion controls the initial steps of germ cell migration in the mouse. Dev Cell. 2005 Dec;9(6):723-4.
Sinner D, Kirilenko P, Rankin S, Wei E, Howard L, Kofron M, Heasman J, Woodland HR, Zorn AM. Global analysis of the transcriptional network controlling Xenopus endoderm formation. Development (Cambridge, England). 2006 May;133(10):1955-66.
Sartor MA, Zorn AM, Schwanekamp JA, Halbleib D, Karyala S, Howell ML, Dean GE, Medvedovic M, Tomlinson CR. A new method to remove hybridization bias for interspecies comparison of global gene expression profiles uncovers an association between mRNA sequence divergence and differential gene expression in Xenopus. Nucleic Acids Res. 2006 Jan 5;34(1):185-200.
