Research Descriptions
Faculty in the Division of Endocrinology direct ground breaking, innovative basic and clinical research projects.
Basic Research
Placenta
- Regulation of human placental and uterine decidual development (Dr. Stuart Handwerger)
- Regulation of human placental lactogen and prolactin gene expression (Dr. Stuart Handwerger)
Immunology of type 1 diabetes
- Development of animal models to study the pathogenesis of type 1A diabetes mellitus (Dr. Jonathan Katz)
- Role of T-lymphocytes in the pathogenesis of type 1A diabetes mellitus (Dr. Jonathan Katz)
Clinical Research
Endocrinology
- Triptorelin for ovary protection in childhood onset lupus (Drs. Susan Rose , Peggy Stenger)
- Healthy Bone Study (Drs. Deborah Elder, Susan Rose)
- Polycystic Ovary Disease (Dr. Deborah Elder)
- Urinary phthalates in children with early puberty (Dr. Peggy Stenger)
Head trauma
- Endocrinopathies after traumatic brain injury (Drs. Susan Rose, Philippe Backeljauw)
- Hypopituitarism in survivors of traumatic, non-accidental brain injury (Drs. Susan Rose)
Childhood Cancer
- The endocrine consequences of childhood cancer (Dr. Susan Rose)
Fanconi’s Anemia
- Thyroid hormone in children with Fanconi’s anemia (Dr. Susan Rose)
- Carbohydrate abnormalities in children with Fanconi’s anemia (Drs. Susan Rose and Deborah Elder)
- Endocrinopathies in bone marrow failure syndrome (Drs Susan Rose, Meilan Rutter)
- Oxandrolone treatment of bone marrow aplasia in children with Fanconi’s anemia (Dr. Susan Rose)
Turner Syndrome
- Clinical outcomes in individuals with Turner Syndrome (Dr. Philippe Backeljauw)
Treatment with Insulin-like Growth Factor
- Recombinant human insulin-like growth factor-1 (rhIGF) treatment of pre-pubertal children with growth failure associated with primary insulin-like growth factor deficiency (Dr. Philippe Backeljauw)
- Recombinant human insulin-like growth factor-1 (rhIGF) treatment in children with short stature due to growth hormone insensitivity syndrome (Dr. Philippe Backeljauw)
- Treatment of individuals with Duchenne Muscular Dystrophy with IGF-1 (Drs. Philippe Backeljauw, Susan Rose, Meilan Rutter)
Treatment with Growth Hormone
- Norditropin National Registry (Dr. Philippe Backeljauw)
- GeNeSIS (Drs. David Repaske, Philippe Backeljauw)
- Genentech National Cooperative Growth Study (NCGS) (Dr. Susan Rose)
- Kabi International Growth Study (Dr. Susan Rose)
- Treatment of Pediatric Crohn’s Disease with growth hormone (Dr. David Klein)
Obesity
- Treatment and prevention of atypical antipsychotic induced obesity (Dr. David Klein)
- Prevention of childhood obesity [Micronesia and underserved area in Cincinnati] (Dr. David Klein)
- Epidemiology of obesity (Dr David Klein)
- Carbohydrate disease in overweight individuals (Dr. Nancy Crimmins)
- Teen bariatric surgery – endocrine outcomes (Drs. Lawrence Dolan, Deborah Elder)
Type 1 Diabetes
- TRAILNET: Immunologic interventions to prevent type 1A diabetes (Dr. Nancy Crimmins)
- Self-Management in Adolescents and Research in Type 1 diabetes: the SMART study – behavior mediators and predictors of adherence to insulin therapy (Dr. Lawrence Dolan)
- Depression in children and adolescents with type 1 diabetes (Dr. Lawrence Dolan)
- Quality Improvement: Health care strategies to improve outcomes in type 1 diabetes (Dr. Lawrence Dolan)
- Eating behaviors and fear of hypoglycemia in families with children under 6 years of age with type 1 diabetes (Dr. Lawrence Dolan)
Type 2 Diabetes
- Beta cell function in adolescents with type 2 diabetes (Dr. Deborah Elder)
- Subclinical cardiovascular disease in adolescent with type 2 diabetes (Dr. Lawrence Dolan)
Cystic Fibrosis Related Diabetes
- Low dose long acting insulin therapy in individuals with cystic fibrosis (Drs. Deborah Elder, Lawrence Dolan)
Epidemiology of Diabetes
- SEARCH for Diabetes in Youth (Drs. Lawrence Dolan, Nancy Crimmins)
- Epidemiology of obesity, insulin resistance, and type 2 diabetes (Drs. Lawrence Dolan, Nancy Crimmins)
Intrauterine Hyperglycemia
- Fetal exposure to maternal hyperglycemia – fetal, neonatal, and long-term outcomes (Drs. Lawrence Dolan, Nancy Crimmins)
