Viral Vector Core
Faculty Director
Han van der Loo, PhD 513-475-4093 (Ext.1)
Purpose
The Cincinnati Children's Hospital Medical Center Viral Vector Core provides high quality research grade vector production services and provides manufacturing of cGMP-grade viral vectors for clinical application.
Viral Vector Products
- Retroviral vectors
- Lentiviral vectors
- Generation of stable producer lines
Viral Vector Services
- Vector titer by functional assay
- Vector titer by PCR
- Vector concentration
- Sterility testing
- Mycoplasma testing
- RCR and RCL
- Training and vector development
Non-GMP quality control testing listed above is provided in coordination with the Translation Trials Development and Support Laboratory. Research-grade AAV and adenoviral vectors are made available through a collaboration with the Columbus Children's Research Institute. Vector development is provided in collaboration with Dr. Axel Schambach and Prof. Dr. Christopher Baum, at the Department of Experimental Hematology at the Hannover Medical School in Hannover, Germany.
Location
Viral Vector Core for research-grade vector, Location R, Research Foundation Building, 6503. Vector Production Facility, 3rd floor, Bio/Start Room 3060, located in the Hoxworth Blood Center building.
Fee Structure
The costs for services are charged to the account listed by the investigator. Overall, fees have been subsidized to allow cost efficiency to investigators. Contact the VVC for a pricing overview or for a specific quote.
Additional Information
Open to faculty at the Research Foundation, the University of Cincinnati, the Genome Research Institute, members of OSUCCC, and other researchers as allowed by core capacity.
