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Experimental Hematology and Cancer Biology

Dao Pan, PhD

Title

Assistant Professor

Email

Dao.Pan@cchmc.org

Phone

513-636-6315

Fax

513-636-1330

Credentials

PhD: University of Minnesota, Minneapolis, MN, 1997

MS: Peking Normal University, Beijing, China, 1991

BS: Peking Normal University, Beijing, China, 1988

Awards and Honors

Best Teaching Assistant Award, University of Minnesota, 1996

Keystone Symposia on Molecular and Cellular Biology Travel Award, National Institutes of Health Grant E6, April 1997

Research

Connect to Dao Pan's laboratory webpage

Research Grants and Contracts

U54 HL70871-01 (Joiner) NIH/NHLBI 09/01/05-03/31/08
Project 4: KCI Cotransporter Gene Expression; Role (PI)

R21 AI061703 (Pan) NIAID 04/2005 - 03/2007
In Vivo Adult Stem Cell Gene Transfer: Implication for treatment of MPS Type I

Publications, Most Recent

Connect to Dao Pan's publications on PubMed

Pan D, Stroncek DF, Whitley CB. Improved gene transfer and normalized enzyme levels in primitive hematopoietic progenitors from patients with mucopolysaccharidosis type I using a bioreactor.J Gene Med. 2004 Dec;6(12):1293-303.

Hartung SD, Frandsen JL, Pan D, Koniar BL, Graupman P, Gunther R, Low WC, Whitley CB, McIvor RS. Correction of metabolic, craniofacial, and neurologic abnormalities in MPS I mice treated at birth with adeno-associated virus vector transducing the human alpha-L-iduronidase gene.Mol Ther. 2004 Jun;9(6):866-75.

Graupman P, Pan D, Konair B, Hartung S, McIvor S, Whitley C, Low W, Lam CH. Craniofacial abnormalities in a murine knock-out model of mucopolysaccharidosis I H: a computed tomography and anatomic study.J Craniofac Surg. 2004 May;15(3):392-8.

Presentations, Most Recent

DN Worsham, K Bohn, D Kuhel, DA Williams, C von Kalle, and D Pan. "In vivo adult stem cell gene therapy in mice by in situ delivery of a self-inactivating lentiviral vector using intrafemoral injection." Annual meeting of American Society of Gene Therapy, St. Louis, MO, June 1-5, 2005, Oral presentation, international.

D Pan, C von Kalle, DA Williams, DN Worsham, K Bohn, and C Lutz. In Vivo Bone Marrow Stem Cell Gene Transfer In Mice By In Situ Delivery Of A 3rd-Generation Lentiviral Vector Using Intrafemoral Injection. Annual meeting of American Society of Hematology, San Diego, CA, Dec. 4-7, 2004. Poster presentation, international.

D Pan, R Gunther, JL Frandsen, T Kafri, RS McIvor and CB Whitley. Systemic Delivery of a 3rd-generation Lentiviral Vector into Iduronidase-deficient Neonatal Mice with Observation of In Vivo Hematopoietic Stem Cell Gene Transfer. Annual meeting of American Society of Hematology, San Diego, CA, Dec. 6-9, 2003. Oral presentation, international.

D Pan, R Gunther, JL Frandsen, T Kafri, RS McIvor and CB Whitley. Systemic Delivery of a 3rd-generation Lentiviral Vector into Iduronidase-deficient Neonatal Mice with Observation of In Vivo Hematopoietic Stem Cell Gene Transfer. 2nd Annual Midwest Blood Club Symposium, Indianapolis, IN, May 1-2, 2004. Oral presentation, local.

CB Whitley, D Pan, SD Hartung, JS Frandsen, R Gunther, WC Low, SU Walkley, RS McIvor. Intravenous Administration of Lentiviral Vector, or Adeno-associated Virus (AAV) Vector, Produces Metabolic and Phenotypic Correction of Hurler Syndrome in Mice. Annual meeting of American Society of Human Genetics, Los Angeles, CA, Nov. 4-8, 2003. Poster presentation, international.

D Pan, R Gunther, JL Frandsen, T Kafri, RS McIvor and CB Whitley. Correction of Hurler syndrome by a single IV administration of lentiviral vector to newborn mice. Annual meeting of American Society of Gene Therapy, Washington DC, June, 2003. Poster presentation, international.

Professional Organization Memberships

American Society of Human Genetics

American Society of Gene Therapy

Abstracts


Books

Ge H and Pan D (1989). Australian National Antarctic Research Exploration, China Ocean Press (edition).

Special Interests

Hematopoietic stem cells, Mesenchymal stem/progenitor cells, Gene therapy, Human genetics, Translational research, Lysosomal storage diseases

Related Areas

This person works in these other areas at Cincinnati Children's Hospital Medical Center: