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Experimental Hematology and Cancer Biology

Qishen Pang, PhD

Title

Associate Professor of Pediatrics

Email

qishen.pang@cchmc.org

Phone

513-636-1152

Fax

513-636-3768

Credentials

PhD: Oregon State University, Corvallis, Oregon, 1993

Postdoctoral Fellow: Oregon Health Sciences University, Portland, OR, 2000

Awards and Honors

2001 Northwest Health Foundation Research Award

2008 Leukemia Lymphoma Society Scholar Award

Research

Connect to Qishen Pang's laboratory webpage

Research Grants and Contracts

NIH (Pang) 07/2005-04/2009
Role of FA protein complex in hematopoiesis

NIH (Pang) 07/2004-04/2009
Role of Nucleophosmin in FA-evolved Leukemia

Publications, Most Recent

Connect to Qishen Pang's publications on PubMed

Zhou Y, Du W, Koretsky T, Bagby GC, Pang Q. (2008) TAT-mediated intracellular delivery of NPM-derived peptide induces apoptosis in leukemic cells and suppresses leukemogenesis in mice. Blood, 2008 Jun 23. [Epub ahead of print].

Zhang X, Shang X, Guo F, Kirby M, Murphy K, Kelly P, Reeves L, Williams DA, Smith FO, Zheng Y, Pang Q. (2008) Defective homing is associated with altered Cdc42 activity in cells from Fanconi anemia group A patients.Blood, 2008 Jun 18. [Epub ahead of print].

Li J, Sejas DP, Zhang X, Qiu Y, Nattamai KJ, Rani R, Rathbun, KR, Geiger H, Williams DA, Bagby GC, Pang Q. (2007) TNF- induces leukemic clonal evolution ex vivo in Fanconi anemia group C stem cells. J. Clin. Invest. 117:3283-3295.

Sejas DP, Rani R, Qiu Y, Zhang X, Fagerlie SR, Nakano H, Williams DA, Pang Q. (2007) Inflammatory reactive oxygen species-mediated hematopoietic suppression in Fancc-deficient mice. J. Immunol. 178: 5277-5287.

Zhang X, Sejas DP, Qiu Y, Williams DA, Pang Q. (2007) Inflammatory reactive oxygen species promote and cooperate with Fanconi anemia mutation for hematopoietic senescence. J. Cell Science. 120:1572-1583.

Li J, Sejas DP, Burma, S, Chen, DJ, Pang Q. (2007) Nucleophosmin suppresses oncogene-induced apoptosis and senescence and enhances oncogenic cooperation in cells with genomic instability. Carcinogenesis. 28:1163-1170.

Li J, Sejas DP, Rani R, Koretsky T, Bagby GC, Pang Q. Nuecleophosmin regulates cell cycle progression and stress response in hematopoietic stem/progenitor cells. J Biol Chem. 2006 281:16536-16545.

Professional Organization Memberships

American Society of Hematology

International Society for Experimental Hematology

Abstracts


Special Interests

Signal transduction in Fanconi anemia and its evolution to leukemia

Related Areas

This person works in these other areas at Cincinnati Children's Hospital Medical Center: