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Experimental Hematology and Cancer Biology

Thomas B. Leemhuis, PhD

Appointment

Associate Professor, Director of Cellular Therapy, Hoxworth Blood Center

Email

thomas.leemhuis@uc.edu

Phone

513-558-1553

Fax

513-558-6614

Credentials

BS: Microbiology, Indiana University, 1978.

MS: Immunology, Purdue University, 1985.

PhD: Indiana University School of Medicine, Indianapolis, IN, 1993.

Research Grants and Contracts

Co-investigator; CCHMC protocol # 01-11-3. "Donation of Peripheral Blood Stem Cells for Use in Experiments Involving In Vitro Expansion and Gene Transfer." David Williams, PI.

Co-Investigator; Collection of Hematopoietic Cells from Patients with Fanconi Anemia for Future Autologous Re-infusion and Research.; Patrcik Kelly, PI.

Co-Investigator; Gene Therapy for Patients with Fanconi Anemia, Genotype A; Patrick Kelly, PI.

Co-Investigator; A Pilot Study of BCNU and Temozolomide Combined with O6BG for Treatement of High-Grade Glioma, Using Autologous Peripheral Blood Stem Cells Genetically Modified for Chemoprotection. Lars Wagner and Christof Kalle, PI.

Co-Investigator; Processing, Storage, and Disposition of Umbilical Cord Blood Cells for Research Purposes Only. Kurt Schibler, PI.

Sponsor; IND #11147 CD34-Selected Allogeneic Peripheral Blood Progenitor Cell Infusion Product.

Publications, Most Recent

Connect to Thomas Leemhuis' publications on PubMed

Leemhuis T, S Wells, C Scheffold, M Edinger, and RS Negrin. A phase I trial of autologous cytokine-induced killer cells for the treatment of relapsed hodgkin disease and non-hodgkin lymphoma.Biol Blood Marrow Transplant. 2005 Mar;11(3):181-7.

Boyer MW, TG Gross, B Loechelt, T Leemhuis, A Filipovich, and RE Harris. Low risk of graft-versus-host disease with transplantation of CD34 selected peripheral blood progenitor cells from alternative donors for Fanconi anemia.J Pediatr Hematol Oncol. 2003 Nov;25(11):890-5.

Professional Organization Memberships

  • International Society for Cellular Therapy
  • American Society for Blood and Marrow Transplantation
  • American Society of Blood Banks

Abstracts

Balcik B, Wu L, Griggs P, and Leemhuis T. Improved post-thaw viability and engraftment kinetics after reducing the DMSO concentration and adding hetastarch to the cryoprotectant solution used to cryopreserve heatopoietic cell populations. Cytotherapy 7(suppl 1) 59a, 2005.

Balcik, B., K Bohn, I Jurickova, C Lutz, L Reeves, T Leemhuis, D Williams, C vonKalle, and P Kelly. Identifying optimal in vitro techniques for clinical hematopoietic cell gene transfer trials. Exp Hem 32(7):165a, 2004.

Leemhuis T, Israel DS, Inglish P, Jurickova I, Von Kalle C, Williams DA, Kelly P. Thawing and selecting CD34+ progenitor cells from cryopreserved cord blood. Cytotherapy 5(5):437, 2003.