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Reprinted with permission from Cancer Cell Volume 7, Number 1, Issue of January 2005.
Miller, S.J., Jessen, W.J., Mehta, T., Hardiman, A., Sites, E., Kaiser, S., Jegga, A., Li, H., Upadhyaya, M.., Giovannini, M., Muir, D., Wallace, M.R., Lopez, E., Serra, E., Lazaro, C., Stemmer-Rachamimov, A., Page, G., Aronow, B.J. and Ratner, N. Integrative genomic analyses show altered Schwann cell development in Neurofibromatosis tumors and implicate SOX9 as an addicting oncogene (2009) EMBO Mol. Medicine, 1(4): 236-248.
Williams, J.P., Wu, J., Johansson, G., Rizvi, T., Miller, S.C., Geiger, H., Malik, P., Li, W., Mukouyama, Y., Cancelas, J.A. and Ratner, N. (2008) Nf1 mutation expands an EGFR-dependent peripheral nerve progenitor population that confers neurofibroma tumorigenic potential. Cell Stem Cell, 3(6):658-69.
Wu, J., Williams, J.P., Rizvi, T.A., Kordich, J.J., Witte, D., Meijer, D., Stemmer-Rachamimov, A.O., Cancelas, J.A. and Ratner, N. (2008) Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog expressing cells. Cancer Cell, 13(2), 105–116.
Monk, KR, Wu, J, Williams, JP, Meinhardt, BA, Fitzgerald, ME, Filippi, M, and Ratner, N. (2007) Mast cells can contribute to axon-glial dissociation and fibrosis in peripheral nerve, Neuron Glial Biology 3(3):233-44.
Related Web Sites
National Institute of Neurological Disorders and Stroke http://www.ninds.nih.gov/news_and_events/news_articles/news_neurofibroma_mouse_model.htm
EMBO Molecular Medicine http://www.embomolmed.org/details/journalArticle/267667/Neurofibromatosis_and_lessons_for_the_war_on_cancer.html
The National Neurofibromatosis Foundation
Society of Neuroscience
American Association for Cancer Research
National Multiple Sclerosis Society
Nf1 Microarray Consortium
