Overview
The Division of Experimental Hematology and Cancer Biology at Cincinnati Children's Hospital Medical Center focuses on research at the bench level and translating the gained knowledge into new clinical therapies. The goal of much of the basic research is to develop novel therapies that can have clinical application. The Division employs talented researchers, research assistants, graduate assistants, postdoctoral fellows, and support staff to work in the following developing programs.
Jose Cancelas, MD, PhD (Hoxworth Blood Center)- Program Leader
Marie-Dominique Filippi, PhD
Hartmut Geiger, PhD
Thomas Leemhuis, PhD (Hoxworth Blood Center)
David Williams, MD
The Stem Cell Program studies the biology of hematopoietic stem and progenitor cells seeking to understand the factors regulating the proliferation and differentiation of these cells.
Punam Malik, MD - Program Leader
Christof von Kalle, MD
Christopher Baum, MD
Timothy Cripe, MD, PhD (Division of Hematology/Oncology)
Timothy M. Crombleholme, MD, FACS, FAAP (Division of Pediatric and Thoracic Surgery)
Thomas Moritz, MD
Dao Pan, PhD
The Molecular and Gene Therapy Program focuses on developing genetic approaches to treat inherited genetic diseases and cancer, use gene delivery to study disease pathophysiology, develop novel stable gene delivery vectors, and study safety of permanent gene delivery into cells, with the goal of facilitating translation of gene therapy research into clinical trials.
Stella Davies, MB BS, PhD, MRCP - Program Leader (Division of Hematology/Oncology)
James Mulloy, PhD
Paul Andreassen, PhD
The Leukemia Biology Program focuses on developing a better understanding of DNA sequences mediating differential responses to DNA - damaging agents and repair mechanisms relevant to cellular resistance and attempt to utilize this knowledge to improve tumor sensitivity and increase resistance of normal cells.
Yi Zheng, PhD - Program Leader, Interim Division Director
Yi Gu, PhD
Theodosia Kalfa, MD, PhD (Division of Hematology/Oncology)
Ruhikanta Meetei, PhD
Qishen Pang, PhD
The goal of the Cell Signaling Program is to explore the complex signaling mechanisms involved in hematopoiesis, tumorigenesis and metastasis.
Nancy Ratner, PhD - Program Leader
Tilat Rizvi, PhD
Timothy Cripe, MD, PhD (Hematology/Oncology)
Susanne Wells, PhD (Hematology/Oncology)
Joe Palumbo, MD (Hematology/Oncology)
The goal of the Cancer Biology Program is to understand the molecular, cell-cell and cell-matrix interactions that are deregulated in tumor genesis to develop better markers of tumor function and effective tumor therapies.
H. Leighton Grimes, PhD- Program Leader
The Cancer Pathology Program is a joint effort of the Division of Experimental Hematology and Cancer Biology and the Division of Pathology. Researchers in this group focus upon the molecular cause of cancer with emphasis on basic research which translates to understanding patient outcomes with current treatments, as well as discovering novel mechanisms of therapeutic intervention. Faculty postions currently open.
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For more information visit Translational Research Cores.
For additional information, please contact Dr. Yi Zheng, Division of Experimental Hematology and Cancer Biology, at 513-636-0364. The Division of Experimental Hematology and Cancer Biology can be found in Room 7.205 of Location S (Research Foundation Building).
