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Cancelas Lab

Jose A Cancelas Perez, MD, PhD

Title

Director of Research, Hoxworth Blood Center; Director of Flow Core; Associate Professor of Pediatrics

Appointment

Associate Professor of Pediatrics, University of Cincinnati

Email

jose.cancelas@uc.edu

Phone

513-558-1324

Fax

513-558-1522

Credentials

MD: Autonomous University of Madrid, Spain, 1989.

Residency: Hematology and Hematotherapy, University of Alcala de Henares, Madrid, Spain, 1993.

PhD: Faculty of Medicine, University of Alcala de Henares, Madrid, Spain, 1996.

Position History

  • 2005-present, Clinical Consultant of the Translational Trial Development & Support Laboratory, Division of Experimental Hematology, Children's Hosp. Med. Center, Cincinnati, OH.; Medical Director for Cell Therapies, Hoxworth Blood Center, Univ. of Cincinnati, Cincinnati, OH.; Flow Cytometry Core Facility Director – Experimental Hematology, Children's Hosp. Med. Center, Cincinnati, OH.
  • 2003-present, Associate Professor of Pediatrics, U. of Cincinnati Med. Ctr, Cincinnati, OH; Director of Research, Hoxworth Blood Center, U. of Cincinnati Med. Ctr, Cincinnati, OH
  • 2002-2003, Clinical fellow of Blood Bank and Transfusion Medicine, Hoxworth Blood Center, Cincinnati, OH
  • 2001-2003, Visiting scientist-Research Associate, Exp. Hematology Division, Children's Hosp. Med. Center, Cincinnati, OH.
  • 1999 to 2001, Director, Flow Cytometry / Cell Isolation Core Facility, Institut de Recerca Oncologica, Barcelona, Spain.
  • 1999 to 2001, Researcher, Cancer Research Center, Barcelona, Spain.
  • 1994 to 1997, Director, Flow Cytometry / Cell Isolation Core Facility, Institut de Recerca Oncologica, Barcelona, Spain.
  • 1994 to 1997, Researcher, Cancer Research Center, Barcelona, Spain.

Awards and Honors

  • 2005, UC Summer Fellowship Award
  • 2005, Co-organizer of the III Midwest Blood Group Meeting
  • 2005, United States National Blood Foundation Award
  • 2004, AABB Baxter-Fenwal Award (Faiqa Sadique, MT (SBB))
  • 2004, Co-organizer of the second Midwest Blood Group Meeting
  • 2003, Co-organizer of the first Midwest Blood Group Meeting
  • 1999, Travel Award, International Society of Experimental Hematology
  • 1997, Areces Fund Fellowship Award
  • 1994, Spanish Health Ministry fellowship Award

Research

Connect to Jose Cancelas' laboratory pages

Publications, Most Recent

Connect to Jose Cancelas' publications on PubMed

Cancelas JA, Lee AW, Prabhakar R, Stringer KF, Zheng Y, Williams DA. Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization. Nat Med. 2005 Aug;11(8):886-91.

Chandra S, Levran O, Jurickova, Maas C, Kapur R, Schindler D, Henry R, Milton K, Batish SD, Cancelas JA, Hanenberg H, Auerbach AD, Williams DA. A rapid method for retrovirus mediated identification of complementation groups in Fanconi anemia patients. Mol Ther. 2005 Nov;12(5):976-84.

Jansen M, Yang FC, Cancelas JA, Bailey JR, Williams DA. Rac2-deficient hematopoietic stem cells show defective interaction with the hematopoietic microenvironment and long-term engraftment failure. Stem Cells. 2005 Mar;23(3):335-46.

Gu Y, Filippi MD, Cancelas JA, Siefring JE, Williams EP, Jasti AC, Harris CE, Lee AW, Prabhakar R, Atkinson SJ, Kwiatkowski DJ, Williams DA. Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases. Science. 2003 Oct 17;302(5644):445-9.

Professional Organization Memberships

  • 2003 to Present, European Hematology Association
  • 2003 to Present, American Association of Blood Banks
  • 2002 to Present, International Society of Experimental Hematology
  • 1997, European Working group for standardization of the detection of minimal residual disease in epithelial neoplasia by immunocytochemistry

Service

  • On-call Physician in transfusion medicine for the Greater Cincinnati area
  • Member of two research projects involving stem cell harvest or transplantation for the DSMB
  • Recruiter of faculty and fellow members for the Division of Experimental Hematology and Transfusion Medicine Program (Hoxworth Blood Center)
  • Manuscript reviewer for Leukemia
  • Organizer of numerous meetings and symposia

Teaching

  • Supervisor of PhD and MS students
  • Member of reviewer committee for PhD thesis
  • Trainer in the Research Division of the Medical Residents of the Program of Pathology at University of Cincinnati
  • Instructor in various postgraduate courses

Special Interests

Hematopoietic stem cell proliferation and differentiation.