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Divisions of Experimental Hematology and Hematology/Oncology participate in the 48th annual American Society of Hematology (ASH) meeting in Orlando, FL from December 9-12.

From December 9-12, 2006, thousands of physicians and scientists gathered in Orlando, FL to participate in the annual ASH meeting.  Cincinnati Children's Hospital Medical Center sent over 30 of its members from the divisions of Experimental Hematology and Hematology/Oncology to participate in this conference.  Many Cincinanti Children's Hospital participants were honored with the opportunity to present their research in different sessions.

Oral Presentations

Lina Li
"Deficiency of Bone Marrow Stromal Cx43 Expression Induces Hematopoietic Progenitor Homing Deficiency and Cell−Cycle Arrest of Hematopoietic Stem Cells and Progenitors."

Deepika Bhatla
"Cytidine Deaminase Genotype Modifies the Toxicity of Therapy for Childhood AML."
 
Linda Yang
"Cdc42 is Critical for Multi-lineage Blood Cell Development from Hematopoietic Stem and Progenitor Cells." 

Shushun Li
"T Cell Lymphopenia In Rhoh-/- Mice Results From Combined Defects Of T Cell Migration And IL-7-Regulated Naïve T Cell Homeostasis."

Theodosial Kalfa
"Deficiency of Rac1 and Rac2 GTPases Perturbs Erythroid Proliferation and Differentiation but Not Enucleation."

Joe Palumbo
"Tumor cell-associated tissue factor supports metastatic potential through both NK cell dependent and -independent mechanisms."

Xiaoling Zhang
"Defective Adhesion, Migration and Homing Are Associated with Altered Rho GTPase Activity in Cells from Fanconi Anemia Patients."

Eric Mullins
"Conditional Disruption of the Murine Prothrombin Gene."

John Perentesis
"Pharmacogenetic Predictors of Toxicity in Dose-Intensive Therapy for Pediatric Advanced-Stage Hodgkin's Lymphoma."

Poster Presentations

Yoshi Yamada
"SCF and IL-5 Synergize with FIP 1L 1/PDGFR To Induce Mastocytosis in a Chronic Eosinophillic Lukemia Murine Model."

Gerlinde Layh-Schmitt
"T Cell Acute Lymphoblastic Leukemia Originates from a Differentiation Block in T Cell Development Due to Aberrant Expression of LMO2 and SCL(TAL1)."

Ondrej Krejci
"AML1-ETO Inhibits DNA Repair Pathways and Promotes the Accumulation of DNA Damage and the Activation of p53."

Eric Mullins
"Conditional Disruption of the Murine Prothrombin Gene."

Haiming Xu
"P190-B RhoGAP Is Critical For Hematopoietic Stem/Progenitor Cell Homing and Short Term Engraftment."

Abdullah Ali
"Identification and Partial Characterization of Fanconi Anemia Associated Polypeptides (FAAPs) Using a Versatile Multiprotein-Complex Purification Method."

Andrew Lee
"Improved Engraftment of Bone Marrow and Mobilized Peripheral Blood Stem Cells in a Fanconi Anemia Murine Model."
 
Junping Wei  
"Immortalization of Human HSPC by a Self-Renewal Signal Coupled with Telomere   Maintenance."

Hartmut Geiger
"A Critical Role for the Retinoblastoma Tumor Suppressor Gene in Hematopoietic Stem Cells."

James Mulloy
"Leukemic Transformation of Primary Human CD34+ Progenitor Cells by MLL-AF9 Recapitulates the Phenotype and Gene Expression Profile of MLL Rearranged AML."
 
Clint Joiner
"Alternative Splicing within Exon 1 of the KCl Cotransporter-3 (KCC3) Gene Results in Novel Transcripts in Erythroid Cells."

Clint Joiner
"Functional Comparison of Red Cell KCl Cotransporter Isoforms, KCC1, KCC3, and KCC4."