Divisions of Experimental Hematology and Hematology/Oncology participate in the 50th annual American Society of Hematology (ASH) meeting in San Francisco, CA from December 6-9
From December 6-9, 2008, almost 24,000 physicians and scientists gathered in San Francisco, CA to participate in the 50th annual ASH meeting
Cincinnati Children's Hospital Medical Center sent over 40 of its members from the divisions of Experimental Hematology and Hematology/Oncology to participate in this conference. Many Cincinnati Children's Hospital participants were honored with the opportunity to present their research in different sessions.
ORAL PRESENTATIONS
Joe Palumbo
“Mechanisms Coupling Thrombin-Mediated Proteolysis to Metastasis.”
Chinavenmeni Velu
“Deregulation of MicroRNA Underlies Severe Congenital Neutropenia Pathogenesis.”
Paritha Arumugam
“The End of the Chicken Hypersensitive Site-4 Insulator Has Properites Similar to the Insulator Core and is Necessary in Conjunction with the Core for Full Insulator Activity.”
Wei Liu
“Mobilization of Hematopoitic Stem/Progenitor Cells by a Cdc42 Activity-Specific Inhibitor.”
Eric Mullins
“Genetic Elimination of Prothrombin in Adult Mice Results in Fatal Spontaneous Hemorrhage in the Heart and Central Nervous System.”
Amitava Sengupta
“Leukemic Stem Cells and Progenitors Demonstrate Impaired Interaction with the Hematopoietic Microenvironment in Vivo in an Inducible Murine Model of Chronic Myelogenous Leukemia.”
Fukun Guo
“The Rho GTPase Cdc42  essential for lymphocyte development and Activation.”
Marie-Dominique Filippi
“Absence of the Rho GTPase Activating Protein Enhances Long Term Hematopoietic Stem Cell Engraftment.”
Marie-Dominique Filippi
“Rho GTPase CDC42 Maintains Neutrophil Polarity Axis during Directed Migration by Regulating CD11b Integrin Signals through Microtubules.”
POSTER PRESENTATIONS
Meghan Rojas
“Ajuba Functions as an ADAC-Dependent Co-Repressor for Autoregulation of Growth Factor Independent-1 Transcription Factor.”
Aditya Chaubey
“GFI1 is a Tumor Suppressor in Myeloid Progenitors”
Amitava Sengupta
“Rac2 GTPase Activation is Necessary for Development of p190-BCR-ABL-Induced B-Cell Acute Lymphoblastic Leukemia.”
Melissa Rayburg
“Functional Polymorphisms in Oxidant Metabolism and DNA Repair Pathways and Risk of Leukemia and Transient Myeloproliferative in Children with Down Syndrome.”
Dao Pan
“High Level Production of a Lysosomal Enzyme from HSC-Derived Erythroid Cells for Therapeutic Correction of Hurler Syndrome in Mice.”
Junping Wei
“Rac GTPases are Required for MLL-AF9-Inducted Mixed Lineage Leukemia.”
Chinavenmeni Velu
“The oncoprotein regulats Hematopoietic Stem Cell Fitness and Functions as a Corepressor for Ffi1.”
Emily Bosco
“Rac1 GTPase Targeting Inhibitis p53-Deficiency Mediated Lymphomagenesis.”
Xiaoling Zhang
“A Cell-Autonomous Defect of Bone Marrow Hematopoietic Stem/Progenitor Cells and Impaired Stromal Function in FA-a Patients.”
Wei Du
“Cdk1-Dependent Phosphorylation of NPM Overrides G<sub>2</sub>/M Checkpoint and Increases Leukemic Blasts in Mice.”
Han vanderLoo
“Production of High Titer cGMP-Grade SIN Gamma-Retroviral Vectors by Transfection in a Closed System Bioreactor.”
Clinton Joiner
“Structural and Functional Interactions of KCI Cotransport Proteins KCC1 and KCC3 in Sickle and Normal Erythrocyte Membranes.”
Marnie Hall
“Pharmacological Inhibition of EGFR Signaling Enhances G-CSF Induced Hematopoietic Stem Cell Mobilization.”
Marnie Hall
“Intravital Imagining of Young and Aged Stem Cells in the Marrow of Long Bones: Visualizing Mammalian Stem Cell Behavior in Real-Time in Vivo.”
Fabrizia Urbinati
“Mechanism of Reduction in titers from Lentivirus Vectors Carrying Chromatin Insulator Elements in the 3’ LTR”
Joe Palumbo
“Hemostatic Factors Support Colitis-Associated Colon Cancer”
Ajay Perumbeti
“Correction of Sickle Cell Anemia with g-Globin gene delivered by Lentivirus vector in the setting of Myeloablative or Reduced Intensity Conditioning and Establishing Critical Determinants for the Successful Gene Therapy for Sickle Cell Disease”
