Publications
These publications may not include all publications authored by division members. Where possible, article titles are linked to an abstract of the article.
2008 Publications
Patel N, Gonsalves C, Yang M-Y, Malik P* and Kalra VK* Placenta growth factor augments endothelin-1 and endothelin-B receptor expression via hypoxia-inducible factor, linking erythropoiesis, pulmonary hypertension and inflammation in sickle cell disease. *Co-Corresponding authors. Blood August 1, 112: 856 - 865
F, Cancelas JA, Hildeman D, Williams DA, Zheng Y. Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development. Blood. 2008 Sep 1;112(5):1767-75.
Yamada Y, Sanchez-Aguilera A, Brandt EB, McBride M, Al-Moamen NJ, Finkelman FD, Williams DA, Cancelas JA, Rothenberg ME. FIP1L1/PDGFRalpha synergizes with SCF to induce systemic mastocytosis in a murine model of chronic eosinophilic leukemia/hypereosinophilic syndrome. Blood. 2008 Sep 15;112(6):2500-7.
Guo F, Cancelas JA, Hildeman D, Williams DA, Zheng Y."Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development." Blood. 112(5):1767-75.
Zhou Y, Du W, Koretsky T, Bagby GC, Pang Q."TAT-mediated intracellular delivery of NPM-derived peptide induces apoptosis in leukemic cells and suppresses leukemogenesis in mice." Blood. 112(6):2474-83.
Zhang X, Shang X, Guo F, Murphy K, Kirby M, Kelly P, Reeves L, Smith FO,Williams DA, Zheng Y, Pang Q. "Defective homing is associated with altered Cdc42 activity in cells from patients with Fanconi anemia group A." Blood. 112(5):1683-6.
Hoskins, E. E., R. W. Gunawardena, et al. (2008). "Coordinate regulation of Fanconi anemia gene expression occurs through the Rb/E2F pathway." Oncogene 27(35): 4798-808.
Mease, P. J., L. M. Arnold, et al. (2008). "Identifying the clinical domains of fibromyalgia: contributions from clinician and patient Delphi exercises." Arthritis Rheum 59(7): 952-60.
Milsom, M. D., M. Jerabek-Willemsen, et al. (2008). "Reciprocal relationship between O6-methylguanine-DNA methyltransferase P140K expression level and chemoprotection of hematopoietic stem cells." Cancer Res 68(15): 6171-80.
Penaud-Budloo, M., C. Le Guiner, et al. (2008). "Adeno-associated virus vector genomes persist as episomal chromatin in primate muscle." J Virol 82(16): 7875-85.
Williams, D. A. (2008). "Progress reported in two studies of clinical gene transfer into the retina." Mol Ther 16(7): 1181.
Zheng, H. C., Y. S. Zheng, et al. (2008). "Arp2/3 overexpression contributed to pathogenesis, growth and invasion of gastric carcinoma." Anticancer Res 28(4B): 2225-32.
Baum, C. (2008). "On target: new envelopes for lentiviral vectors." Mol Ther 16(8): 1349-50.
Bhatla, D., S. M. Davies, et al. (2008). "Reduced-intensity conditioning is effective and safe for transplantation of patients with Shwachman-Diamond syndrome." Bone Marrow Transplant 42(3): 159-65.
Diwan, A., A. G. Koesters, et al. (2008). "Targeting erythroblast-specific apoptosis in experimental anemia." Apoptosis 13(8): 1022-30.
Gao, Y., G. Li, et al. (2008). "Postprandial blood glucose response to a standard test meal in insulin-requiring patients with diabetes treated with insulin lispro mix 50 or human insulin mix 50." Int J Clin Pract.
Guo, F., M. Debidda, et al. (2006). "Genetic deletion of Rac1 GTPase reveals its critical role in actin stress fiber formation and focal adhesion complex assembly." J Biol Chem 281(27): 18652-9.
Johansson, G., Y. Y. Mahller, et al. (2008). "Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors." Mol Cancer Ther 7(5): 1237-45.
Lee, S. J., S. Joffe, et al. (2008). "Individual physician practice variation in hematopoietic cell transplantation." J Clin Oncol 26(13): 2162-70.
Ling, C., M. Ishiai, et al. (2007). "FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway." EMBO J 26(8): 2104-14.
Mahller, Y. Y., B. Sakthivel, et al. (2008). "Molecular analysis of human cancer cells infected by an oncolytic HSV-1 reveals multiple upregulated cellular genes and a role for SOCS1 in virus replication." Cancer Gene Ther.
Marsh, R. A., A. W. Lucky, et al. (2008). "Cutaneous infection with Metarhizium anisopliae in a patient with hypohidrotic ectodermal dysplasia and immune deficiency." Pediatr Infect Dis J 27(3): 283-4.
Modlich, U., A. Schambach, et al. (2008). "Leukemia induction after a single retroviral vector insertion in Evi1 or Prdm16." Leukemia.
Morison, I. M., E. M. Cramer Borde, et al. (2008). "A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia." Nat Genet 40(4): 387-9.
Schmorrow, D. D. and L. M. Reeves (2007). "21st century human-system computing: augmented cognition for improved human performance." Aviat Space Environ Med 78(5 Suppl): B7-11.
Sun, Q., Q. Liu, et al. (2008). "Rapamycin suppresses TLR4-triggered IL-6 and PGE(2) production of colon cancer cells by inhibiting TLR4 expression and NF-kappaB activation." Mol Immunol 45(10): 2929-36.
Thomas, E. K., J. A. Cancelas, et al. (2008). "Rac GTPases as key regulators of p210-BCR-ABL-dependent leukemogenesis." Leukemia 22(5): 898-904.
Wei, J., M. Wunderlich, et al. (2008). "Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia." Cancer Cell 13(6): 483-95.
Will, E., J. Bailey, et al. (2007). "Importance of murine study design for testing toxicity of retroviral vectors in support of phase I trials." Mol Ther 15(4): 782-91.
Williams, D. A., Y. Zheng, et al. (2008). "Rho GTPases and regulation of hematopoietic stem cell localization." Methods Enzymol 439: 365-93.
Wu, X., X. Tu, et al. (2008). "Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling." Cell 133(2): 340-53.
Zheng, Y., W. Bie, et al. (2008). "Functions of p21 and p27 in the Regenerating Epithelial Linings of the Mouse Small and Large Intestine." Cancer Biol Ther 7(6).
Zheng, Y., X. R. Cheng, et al. (2008). "Gene expression patterns of hippocampus and cerebral cortex of senescence-accelerated mouse treated with Huang-Lian-Jie-Du decoction." Neurosci Lett 439(2): 119-24.
Zhou, W., B. Wang, et al. (2008). "Effect of surface decoration of CNTs on the interfacial interaction and microstructure of epoxy/MWNT nanocomposites." Chemphyschem 9(7): 1046-52.
Azizkhan, R. G. and T. M. Crombleholme (2008). "Congenital cystic lung disease: contemporary antenatal and postnatal management." Pediatr Surg Int 24(6): 643-657.
Blanco, J. G., W. M. Leisenring, et al. (2008). "Genetic polymorphisms in the carbonyl reductase 3 gene CBR3 and the NAD(P)H:quinone oxidoreductase 1 gene NQO1 in patients who developed anthracycline-related congestive heart failure after childhood cancer." Cancer 112(12): 2789-95.
Chae, H. D., K. E. Lee, et al. (2008). "Cross-talk between RhoH and Rac1 in regulation of actin cytoskeleton and chemotaxis of hematopoietic progenitor cells." Blood 111(5): 2597-605.
Currier, M. A., R. A. Gillespie, et al. (2008). "Efficacy and safety of the oncolytic herpes simplex virus rRp450 alone and combined with cyclophosphamide." Mol Ther 16(5): 879-85.
Davies, S. M. and A. Bennett (2008). "Understanding the economic and social effects of academic clinical partnerships." Acad Med 83(6): 535-40.
Davies, S. M., M. J. Borowitz, et al. (2008). "Pharmacogenetics of minimal residual disease response in children with B-precursor acute lymphoblastic leukemia: a report from the Children's Oncology Group." Blood 111(6): 2984-90.
Muller, L. U., M. D. Milsom, et al. (2008). "Rapid lentiviral transduction preserves the engraftment potential of Fanca(-/-) hematopoietic stem cells." Mol Ther 16(6): 1154-60.
Mulrooney, D. A., D. C. Dover, et al. (2008). "Twenty years of follow-up among survivors of childhood and young adult acute myeloid leukemia: a report from the Childhood Cancer Survivor Study." Cancer 112(9): 2071-9.
Newrzela, S., K. Cornils, et al. (2008). "Resistance of mature T cells to oncogene transformation." Blood.
Planque, C., L. Li, et al. (2008). "A multiparametric serum kallikrein panel for diagnosis of non-small cell lung carcinoma." Clin Cancer Res 14(5): 1355-62.
Raynard, S., W. Zhao, et al. (2008). "Functional role of BLAP75 in BLM-topoisomerase IIIalpha-dependent holliday junction processing." J Biol Chem 283(23): 15701-8.
Bhatla, D., Gerbing, R. B., Alonzo, T. A., Mehta, P. A., Deal, K., Elliott, J., Meshinchi, S., Geiger, H., Perentesis, J. P., Lange, B. J. and Davies, S. M. "DNA repair polymorphisms and outcome of chemotherapy for acute myelogenous leukemia: a report from the Children's Oncology Group." Leukemia. 2008 Feb;22(2):265-72.
Daria, D., Filippi, M. D., Knudsen, E. S., Faccio, R., Li, Z., Kalfa, T. and Geiger, H. "The retinoblastoma tumor suppressor is a critical intrinsic regulator for hematopoietic stem and progenitor cells under stress." Blood. 2008 Feb 15;111(4):1894-902.
Eapen, M., Zhang, M. J., Devidas, M., Raetz, E., Barredo, J. C., Ritchey, A. K., Godder, K., Grupp, S., Lewis, V. A., Malloy, K., Carroll, W. L., Davies, S. M. and Camitta, B. M. "Outcomes after HLA-matched sibling transplantation or chemotherapy in children with acute lymphoblastic leukemia in a second remission after an isolated central nervous system relapse: a collaborative study of the Children's Oncology Group and the Center for International Blood and Marrow Transplant Research." Leukemia. 2008 Feb;22(2):281-6.
Gardner, S. L., Carreras, J., Boudreau, C., Camitta, B. M., Adams, R. H., Chen, A. R., Davies, S. M., Edwards, J. R., Grovas, A. C., Hale, G. A., Lazarus, H. M., Arora, M., Stiff, P. J. and Eapen, M. "Myeloablative therapy with autologous stem cell rescue for patients with Ewing sarcoma." Bone Marrow Transplant. 2008 Feb 4;
Hansen, M. D., Filipovich, A. H., Davies, S. M., Mehta, P., Bleesing, J., Jodele, S., Hayashi, R., Barnes, Y. and Shenoy, S. "Allogeneic hematopoietic cell transplantation (HCT) in Hurler's syndrome using a reduced intensity preparative regimen." Bone Marrow Transplant. 2008 Feb;41(4):349-53.
Krejci, O., Wunderlich, M., Geiger, H., Chou, F. S., Schleimer, D., Jansen, M., Andreassen, P. R. and Mulloy, J. C. "p53 signaling in response to increased DNA damage sensitizes AML1-ETO cells to stress-induced death." Blood. 2008 Feb 15;111(4):2190-9.
Mahller, Y. Y., Vaikunth, S. S., Ripberger, M. C., Baird, W. H., Saeki, Y., Cancelas, J. A., Crombleholme, T. M. and Cripe, T. P. "Tissue inhibitor of metalloproteinase-3 via oncolytic herpesvirus inhibits tumor growth and vascular progenitors." Cancer Res. 2008 Feb 15;68(4):1170-9.
Tan, W., Palmby, T. R., Gavard, J., Amornphimoltham, P., Zheng, Y. and Gutkind, J. S. "An essential role for Rac1 in endothelial cell function and vascular development." Faseb J. 2008 Feb 1;
Wu, J., Williams, J. P., Rizvi, T. A., Kordich, J. J., Witte, D., Meijer, D., Stemmer-Rachamimov, A. O., Cancelas, J. A. and Ratner, N. "Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells." Cancer Cell. 2008 Feb;13(2):105-16.
Zychlinski, D., Schambach, A., Modlich, U., Maetzig, T., Meyer, J., Grassman, E., Mishra, A. and Baum, C. "Physiological Promoters Reduce the Genotoxic Risk of Integrating Gene Vectors." Mol Ther. 2008 Mar 4;
Gordon, A., Kozin, E. D., Keswani, S. G., Vaikunth, S. S., Katz, A. B., Zoltick, P. W., Favata, M., Radu, A. P., Soslowsky, L. J., Herlyn, M. and Crombleholme, T. M. "Permissive environment in postnatal wounds induced by adenoviral-mediated overexpression of the anti-inflammatory cytokine interleukin-10 prevents scar formation." Wound Repair Regen. 2008 Jan 18;16(1):70-79.
Mehta, P. A. and Davies, S. M. "Allogeneic transplantation for childhood ALL." Bone Marrow Transplant. 2008 Jan;41(2):133-9.
Pan, D., Sciascia, A., 2nd, Vorhees, C. V. and Williams, M. T. "Progression of multiple behavioral deficits with various ages of onset in a murine model of Hurler syndrome." Brain Res. 2008 Jan 10;1188(241-53.
Wise-Draper, T. M. and Wells, S. I. "Papillomavirus E6 and E7 proteins and their cellular targets." Front Biosci. 2008 13(1003-17.
