June 1-2, 2008, Harvard Club of Boston, Boston, MA
The co-organizers and the Cincinnati Children's Research Foundation's Division of Experimental Hematology and Cancer Biology invite you to participate in the Fourth Stem Cell Clonality and Genotoxicity Retreat.
Dear Colleagues,
New challenges and opportunities have been introduced into the field of stem cell gene therapy due to progress that has uncovered both unprecedented success and serious side effects. Improved understanding of the genotoxicity of stem cell manipulation and vector insertion provides the opportunity to increase both our understanding of stem cell physiology and the safety of gene transfer manipulations.
Over the past five years, we have organized the Stem Cell Clonality and Genotoxicity Retreats in conjunction with the American Society of Hematology and American Society of Gene Therapy Annual meetings, alternating between the two in 18 month intervals. These retreats consisted of more than 25 speakers and over 200 participants. (See 2006 Molecular Therapy Meeting Report published in Molecular Therapy) Because of the positive feedback received and, more importantly, as the developments continue to change the way the field looks at and overcomes these issues, we are pleased to host the Fourth Stem Cell Clonality and Genotoxicity Retreat. This year's retreat is being held immediately following the American Society of Gene Therapy meeting in Boston, MA on June 1-2, 2008 at the Harvard Club of Boston. The meeting will take place from 12-5:30 p.m. on June 1 and from 7-4 p.m. on June 2, 2008. The retreat will follow a unique format and will be directed at updating the progress made in understanding normal and abnormal stem cell biology as revealed in part by vector insertional analysis. There will also be sessions on improved vector designs and new vector systems. The substantial and exciting progress the field has made in understanding the mechanisms underlying the evolution of gene-modified cells in vivo, both in animal and in clinical trials will be reviewed.
Please see the links below which will provide you with a preliminary program as well as registration/lodging information. We have been fortunate to confirm the attendance and contributions of 31 of the world's leaders in this field to this intimate exchange of ideas about the current progress and challenges in the field of gene therapy.
We have decided to keep registration costs at a minimum to encourage attendance by trainees. Please be sure to register early as space will be limited. The registration fee prior to April 31, 2008 is $100 and all late registration fees are $125. For further details, please contact Fannie Beasley at 513-636-1333 or via email at Fannie.Beasley@cchmc.org.
Best regards,
Christopher Baum, M.D.
Christof von Kalle, M.D.
Punam Malik, M.D.
David A.Williams, M.D.
Speakers
| A. Aiuti |
D. Emery |
P. Malik |
A. Thrasher |
| S. Armstrong |
M. Grez |
F. Mavilio |
I. Touw |
| C. Baum |
K. Humphries |
L. Naldini |
D. Williams |
| F. Bushman |
Z. Izsvak |
A. Nienhuis |
C. Wilson |
| N. Cartier-Lacave |
C. von Kalle |
D. Persons |
|
| T. Cathomen |
M. Kay |
D. Russell |
|
| M. Cavazzana-Calvo |
H. Kim |
M. Sadelain |
|
| K. Cichutek |
D. von Laer |
B. Sorrentino |
|
| C. Dunbar |
H. Malech |
F.Staal |
|
Organizers
- Christopher Baum, MD
- Adjunct Associate Professor of Pediatrics,
Molecular and Gene Therapy Program
Cincinnati Children's Hospital Medical Center;
Director, Department of Experimental Hematology,
Hannover Medical School, Hannover, Germany - Christof von Kalle, MD
- Adjunct Associate Professor of Pediatrics,
Molecular and Gene Therapy Program
Cincinnati Children's Hospital Medical Center;
Director, National Center of Tumor Disease Professor and Chairman,
Division of Translation Oncology University Hospital Heidelberg and German Cancer Center - Punam Malik, MD
- Associate Professor of Pediatrics
Program Leader, Molecular and Gene Therapy Program
Division of Experimental Hematology
Fellowship Program Director
Deputy Director, Comprehensive Sickle Cell Program
Division of Hematology/Oncology - David Williams, MD
- Chief, Division of Hematology/Oncology
Director, Translational Research for Children's Hospital Boston
Leland Fikes Professor of Pediatrics, Harvard Medical School
Adjunct Professor of Pediatrics
Cincinnati Children's Hospital Medical Center
Sponsored by:
Cincinnati Children's Hospital Medical Center (CCHMC) Division of Experimental Hematology and Cancer Biology, CCHMC Division of Hematology/Oncology, CCHMC Translational Research Initiative, CCHMC Division of Translational Resarch, Boston Chilren's Hospital Takara Bio, Inc. Amgen Charles H. Dater Foundation Deutsche Forschungsgemeinschaft, DFG CONSERT Clinigene For additional information on CME credit, please contact Fannie Beasley.
For further information about the Stem Cell Clonality and Genotoxicity Retreat, please contact Fannie Beasley, Division of Experimental Hematology and Cancer Biology, at 513-636-1333 or via email at Fannie.Beasley@cchmc.org.
