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Alexander G. Miethke, MD

Title

Clinical Fellow

Email

alexander.miethke@cchmc.org

Phone

513-636-9078

Fax

513-636-7805

Credentials

MD: Humboldt-University, Berlin, Germany, 2000.
Residency: General  Pediatrics, CCHMC, Cincinnati, OH, 2002-2004.
Fellowship: Pediatric Gastroenterology, Hepatology, and Nutrition, CCHMC, Cincinnati, OH, 2005-2007.

Awards

American Liver Foundation (ALF) Postdoctoral Research Fellowship, Sponsored by Chronic Liver Disease Consortium

Publications, Most Recent

Liu C; Aronow BJ; Jegga AG; Wang N; Miethke A.; Mourya R; Bezerra JA. Novel resequencing chip customized to diagnose mutations in patients with intrahepatic cholestasis. Gastroenterology. 2007 Jan; 132(1):119-26.

Shivakumar P.; Campbell KM.; Sabla GE.; Miethke A.; Tiao G.; McNeal MM.; Ward RL.; Bezerra JA.: Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-gamma in experimental biliary atresia. J Clin Invest. 2004 Aug; 114(3):322-9.

Miethke A.; Feussner M.; Planitzer G.; Richter H.; Gutsmann M.; Gossrau R.: Localization of NOS-1 in the sarcolemma region of a subpopulation of atrial cardiomyocytes including myoendocrine cells and NOS-3 in vascular and endocardial endothelial cells of the rat heart. Acta Histochem. 2003; 105(1):43-55.

Baum O.; Miethke A.; Wockel A.; Willerding G.; Planitzer G.: The specificity of the histochemical NADPH diaphorase reaction for nitric oxide synthase-1 in skeletal muscles is increased in the presence of urea. Acta Histochem. 2002; 104(1):3-14

Planitzer G.; Miethke A.; Baum O.: Nitric oxide synthase-1 is enriched in fast-twitch oxidative myofibers. Cell Tissue Res. 2001 Nov; 306(2):325-33.

Find publications by Alexander Miethke as listed by PubMed

Recent Presentations

Miethke, A; Shivakumar, P; Bezerra, JA. The role of regulatory T cells in the pathogenesis of experimental biliary atresia.  Poster accepted for presentation at the 7th Annual Meeting of the Federation of Clinical Immunology Societies (FOCIS), June 7-11, 2007, San Diego, CA.

Edward L Pratt Lecture: Obstruction of bile duct is regulated by Interferon-gamma in a mouse model of biliary atresia. Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 2004.

Special Interests

Hepatology.
Biology of Treg lymphocytes
Genetic basis of intrahepatic cholestasis of childhood

Research Interests

Biliary Atresia.
Duchenne Muscular Dystrophy.