Bezerra Lab

Gregg E. Sabla, BS

Title

Senior Research Assistant

Email

sablg0@cchmc.org

Phone

513-636-3518

Fax

513-636-5581

Credentials

B.S.: University of Cincinnati, Cincinnati, OH, 1994.

Publications, Most Recent

Shivakumar P; Sabla G; Mohanty SK; McNeal M; Ward R; Stringer K; Caldwell C; Chougnet C; Bezerra JA. Effector role of neonatal hepatic CD8+ lymphocytes in epithelial injury and autoimmunity in experimental biliary atresia. Gastroenterology 2007 133(1): 268-77.

Shanmukhappa K; Sabla GE; Degen JL; Bezerra JA. Urokinase-type plasminogen activator supports liver repair independent of its cellular receptor. BMC Gastroenterol 2006;6:40.

Mohanty SK; Shivakumar P; Sabla G; Bezerra JA. Loss of interleukin-12 modifies the pro-inflammatory response but does not prevent duct obstruction in experimental biliary atresia. BMC Gastroenterol 2006;6:14.

Carvalho E; Liu C; Shivakumar P; Sabla G; Aronow B; Bezerra JA. Analysis of the biliary transcriptome in experimental biliary atresia. Gastroenterology, 2005;129:713-7.

Shanmukhappa K; Mourya R; Sabla GE; Degen JL; Bezerra JA. Hepatic to pancreatic switch defines a role for hemostatic factors in cellular plasticity in mice. Proc Natl Acad Sci U S A, 2005;102:10182-7.

Shivakumar P; Campbell KM; Sabla GE; Miethke A; Tiao G; McNeal MM; Ward RL; Bezerra JA. Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-g in experimental biliary atresia. J Clin Invest, 2004;114:322-9.

Zhang DY; Sabla G; Shivakumar P; Tiao G; Sokol RJ; Mack C; Shneider BL; Aronow B; Bezerra JA: Coordinate expression of regulatory genes differentiates embryonic and perinatal forms of biliary atresia. Hepatology. 2004 Apr; 39(4):954-62.

Campbell KM; Sabla GE; Bezerra JA: Transcriptional reprogramming in murine liver defines the physiologic consequences of biliary obstruction. J Hepatol. 2004 Jan; 40(1):14-23.

Bezerra JA; Tiao G; Ryckman FC; Alonso M; Sabla GE; Shneider B; Sokol RJ; Aronow BJ: Genetic induction of proinflammatory immunity in children with biliary atresia. Lancet. 2002 Nov 23;360(9346):1653-9.

Currier, AR; Sabla, GE; Locaputo, S; Melin-Aldana, H; Degen, JL; and Bezerra JA.: Plasminogen directs the pleiotropic effects of uPA in liver injury and repair. Am J Physiol Gastrointest Liver Physiol. 2002; 284(3):G508-15

Kelley-Loughnane, N; Sabla, GE; Ley-Ebert, C; Aronow, BJ; Bezerra, JA: Independent and Overlapping Transcriptional Activation During Liver Development and Regeneration in Mice. Hepatology 2002;35:525-534.

Pohl, JF; Melin-Aldana, H; Sabla, GE; Degen, JL and Bezerra, JA.: Plasminogen Deficiency Leads to Impaired Lobular Reorganization and Matrix Accumulation after Chronic Liver Injury. American Journal of Pathology, Vol. 159, No. 6: 2179-2186. December 2001.

Ng, VL; Sabla, GE; Melin-Aldana, H; Kelley-Loughnane, N; Degan, JL; Bezerra, JA: Plasminogen deficiency results in poor clearance of non-fibrin matrix and persistent activation of hepatic stellate cells after an acute injury. Journal of Hepatology. 2001 Dec;35(6):781-9.

Bezerra JA.; Currier, AR.; Melin-Aldana H.; Sabla G.; Bugge TH.; Kombrinck KW.; Degen JL.: Plasminogen Activators Direct Reorganization of the Liver Lobule after Acute Injury. Am J Pathol. 2001 Mar;158(3):921-929.