You-Hai Xu, PhD
Title
Head, Molecular Diagnostics
Appointment
Assistant Professor, Research
Email
you-hai.xu@chmcc.org
Phone
513-636-4542
Fax
513-636-4373
Bio
You-Hai Xu, PhD, is interested in the regulation of gene expression at translation level. Dr. Xu is studying the cellular effect on transgene expression in mammalian system, especially the enzyme (human acid -glucosidase) deficient ex vivo/in vivo system (Gaucher disease). He is also studying translational control mechanism of protein synthesis and associated cellular functions.
Credentials
PhD: Shanghai Institute of Cell Biology, Shanghai, China 1987.
Research
Research interest in translational control of protein synthesis.
Publications, Most Recent
Xu, Y.H.; and Grabowski, G.A.:
1998. Translation inefficiency of human acid-glucosidase in trasduced mammalian cells.Molecular Genetics and Metabolism, 64:87-98.
Xu, Y.H.; and Grabowski, G.A.: 1999. Molecular Cloning and Characterization of Translational Inhibitory Protein That Binds to Coding Sequences of Human Acid beta-Glucosidase and Other mRNAs.Mol Genet Metab 68:441-454.
Related Areas
This person works in these other areas at Cincinnati Children's Hospital Medical Center:
