Human Genetics

Teresa Smolarek, PhD

Title

Assistant Director, Cytogenetics Laboratory

Appointment

Assistant Professor of Clinical Pediatrics, Affiliated

Email

teresa.smolarek@cchmc.org

Phone

513-636-7221

Fax

513-636-4373

Office Location

R-1042, ML 7016

Credentials

PhD: Medical Genetics, Indiana University School of Medicine, 1995

Certification: American Board of Medical Genetics, Clinical Cytogenetics, 2002; Clinical Molecular Genetics, 2005

Research

Genetic Basis of Pulmonary lymphangioleiomyomatosis (LAM); cancer genetics; clinical cytogenetics

Publications, Most Recent

Astrinidis A, Khare L, Carsillo T, Smolarek T, Au P, Northrup H, Petri Henske E (2000): Mutational Analysis in the Tuberous Sclerosis Gene TSC2 in DNA from Women with Pulmonary Lymphangiomyomatosis.J Med Genet 37(1):55-57.

Smolarek TA, Blough RI, Foster RS, Ulbright TM, Palmer CG, Heerema NA (1999): Cytogenetic Analyses of 85 Testicular Germ Cell Tumors: Comparison of Postchemotherapy and Untreated tumors.Cancer Genet Cytogenet 108(1):57-69.

Smolarek TA, Wessner LL, McCormack FX, Mylet JC, Menon AG, Henske EP (1998): Evidence That Lymphangiomyomatosis Is Caused by TSC2 Mutations: Chromosome 16p13 Loss of Heterozygosity in Angiomyolipomas and Lymph Nodes from Women with Lymphangiomyomatosis.Am J Hum Genet 62:810-815.

Blough RI, Vance GH, Henegariu O, Smolarek TA, Sledge GW Jr., Heerema NA (1998): Characterization of multiple chromosome 12p rearrangements in testicular male germ cell tumor cell line 833K and its subclone 64CP by chromosome microdissection.Cancer Genet Cytogenet 106(1):24-9.

Blough RI, Heerema NA, Ulbright TM, Smolarek TA, Roth LM, Einhorn LH (1998): Interphase Chromosome Painting of Paraffin Embedded Tissue in the Differential Diagnosis of Possible Germ Cell Tumors in Man.Mod Path 11(7):634-41.

Blough RI, Smolarek TA, Ulbright TM, Heerema NA (1998): Bicolor fluorescence in situ hybridization detection of chromosome arms 12p and 12q on nuclei from formalin-fixed, paraffin-embedded (PET) testicular germ cell tumors: Comparison with standard metaphase analysis.Cancer Genet Cytogenet 94(2):79-84.

Bhugra B, Smolarek TA, Lynch R, Meloni A, Deaven L, Menon AG (1998): Cloning of a breakpoint cluster region on chromosome 14 in uterine leiomyoma. Cancer Letters 126:119-126.

Cruz M, Elenich LA, Smolarek TA, Menon AG, Monaco JJ (1997): DNA Sequence, Chromosomal Localization, and Tissue Expression of the Mouse Proteasome Subunit Lmp 10 (Psmb 10) Gene.Genomics 45:618-622.

Smolarek TA, Blough RI, Foster RS, Ulbright TM, Palmer CG, Heerema NA (1995): Identification of Multiple Chromosome 12 Abnormalities in Human Testicular Germ Cell Tumors by Two-color Fluorescence in situ Hybridization (FISH).Genes, Chromosom & Cancer 14:252-258.