Hematology / Oncology

Joseph S. Palumbo, MD

Appointment

Research Assistant Professor

Email

joe.palumbo@cchmc.org

Phone

513-636-0670

Fax

513-636-3549

Credentials

MD: Pennsylvania State University College of Medicine, Hershey, PA, 1993.

Residency: Childrens Hospital Medical Center, Cincinnati, OH, 1997.

Fellowship: Childrens Hospital Medical Center, Cincinnati, OH, 2000.

Subspecialty: Pediatric Hematology / Oncology

Awards and Honors

Hewlett Packard Award for Excellence in Pediatric Clinical Clerkship, 1993.
Alpha Omega Alpha National Medical Honor Society, 1992.

Research Grants and Contracts

K08 Mentored Training Award 2003 to 2008.

Publications, Most Recent

Connect to Joe Palumbo's publications on PubMed

Palumbo JS, Talmage KE, Massari JV, La Jeunesse CM, Flick MJ, Kombrinck KW, Hu Z, Barney KA, Degen JL. Tumor cell-associated tissue factor and circulating hemostatic factors cooperate to increase metastatic potential through natural killer cell-dependent and-independent mechanisms. Blood 2007;110:133-141.

Palumbo JS, Degen JL. Mechanisms linking tumor cell-associated procoagulant function to tumor metastasis. Thrombosis research 2007;120 Suppl 2:S22-28.

Flick MJ, LaJeunesse CM, Talmage KE, Witte DP, Palumbo JS, Pinkerton MD, Thornton S, Degen JL. Fibrin(ogen) exacerbates inflammatory joint disease through a mechanism linked to the integrin alphaMbeta2 binding motif. The Journal of clinical investigation 2007;117:3224-3235.

Widemann BC, Salzer WL, Arceci RJ, Blaney SM, Fox E, End D, Gillespie A, Whitcomb P, Palumbo JS, Pitney A, Jayaprakash N, Zannikos P, Balis FM. Phase I trial and pharmacokinetic study of the farnesyltransferase inhibitor tipifarnib in children with refractory solid tumors or neurofibromatosis type I and plexiform neurofibromas. J Clin Oncol 2006;24:507-516.

Palumbo JS, Talmage KE, Massari JV, La Jeunesse CM, Flick MJ, Kombrinck KW, Jirouskova M, Degen JL. Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer cell-mediated elimination of tumor cells.Blood. 2005 Jan 1;105(1):178-85.

Palumbo JS, Zogg M, Talmage K, Degen JL, Weiler H, Isermann BH. Role of fibrinogen- and platelet-mediated haemostasis in mouse embryogenesis and reproduction.J Thromb Haemost. 2004 Aug;2(8):1368-79.

Abstracts/ Presentations

Palumbo JS, Massari JV, La Jeunesse CM, et al. Interplay between tumor cell-assocaited and circulating coagulation factors in establishing metastatic potential. Blood. (2005): 106 (11), 202a. Presented at the American Society of Hematology Meeting 2005.

Palumbo JS, Talmage KE, Massari JV, La Jeunesse CM, Flick, MJ, Jirouskova, M, Degen, JL. Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer-mediated elimination of tumor cells. Blood. (2004): 104(11), 198a. Presented at the American Society of Hematology Meeting 2004.

Professional Organization Memberships

American Society of Pediatric Hematology/Oncology
American Society of Hematology
Children's Oncology Group

Teaching

2005 - present: Lecturer, Pediatric Hematology/Oncology fellowship lecture series; Biochemistry and Cell Biology of Coagulation and Platelet Function.
2003 - present: Lecturer, Pediatric Hematology/Oncology resident lecture series; Diagnosis of Bleeding Disorders
2002 - 2003: Lecturer, Pediatric Hematology/Oncology fellowship lecture series; Langerhans' Cell Histiocytosis.
2002 - 2003: Lecturer, Pediatric Hematology/Oncology resident lecture series; Pediatric Solid tumors.

Abstracts

Palumbo JS, Talmage KE, Massari JV, La Jeunesse CM, Flick, MJ, Jirouskova, M, Degen, JL. Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer-mediated elimination of tumor cells. Blood. (2004): 104(11), 198a. Presented at the American Society of Hematology Meeting 2004.

Palumbo JS, Talmage KE, Liu H, La Jeunesse CM, Witte DP, Degen JL. Mechanisms linking plasminogen and tumor growth in mice. Presented at the IXth International Workshop on Molecular and Cellular Biology of Plasminogen and Activation, 2003.

Palumbo J.S., Talmage KE, Moore CS, Kaplan, LS, and Degen JL. Tumor cell metastatic potential is determined by an interplay between hemostatic factors and natural killer cell function. [Abstract] Blood. (2002): 100(11), 18a. Presented at the American Society Hematology Meeting 2002.

Palumbo J.S., Potter JM, Blagrave TA, Liu H, and Degen JL. The role of plasmin mediated fibrinolysis in tumor growth. Presented at the Gordon Conference on Plasminogen and Fibrinolysis 2002.