Hematology / Oncology

Rachid Drissi, PhD

Appointment

Assistant Professor, University of Cincinnati College of Medicine

Email

rachid.drissi@cchmc.org

Phone

513-636-4266

Fax

513-636-3549

Credentials

BS: Biochemistry, University of Rouen, France, 1983.

MS: Organic Chemistry, University of Rouen, France, 1984.

MS: Biochemistry, University of Paris VI, France, 1988.

PhD: Molecular Biology with Honors, University of Paris VI, France, 1994.

Publications, Most Recent

Sanders RP, Drissi R, Billups CA, Daw NC, Valentine MB, Dome JS. Telomerase expression predicts unfavorable outcome in osteosarcoma. J Clin Oncol 22(18):3790-3797, 2004.

Drissi R*, Bakkenist CJ*, Wu J, Kastan MB, Dome JS. Disappearance of the telomere dysfunction-induced stress response in fully senescent cells. Cancer Res 64:3748-3752, 2004. (*equal contribution)

Drissi R, Zindy F, Roussel MF, Cleveland JL. c-Myc-mediated regulation of telomerase activity is disabled in immortalized cells. J Biol Chem 276:29994-30001, 2001.

Professional Organization Memberships

American Association for Cancer Research

Abstracts

Dome JS, Sanders RP, Drissi R, Billups CA, Daw NC, Gayed P. Telomere maintenance mechanism predicts clinical behavior in human osteosarcoma. AACR, Special Conference in Cancer Research, the Role of Telomeres and Telomerase in Cancer, San Francisco, California. November 3-7, 2004.

Drissi R*, Bakkenist CJ*, Wu J, Kastan MB, Dome JS. ATM activation is a marker of cellular aging and a precursor to replicative senescence. (*equal contribution). AACR 95th Annual Meeting, Orlando, Florida. March 27-31, 2004.

Dome JS, Bockhold C, Wu J, Drissi R. Telomere integrity as determinant of radiation sensitivity in human cells. Meeting on Molecular Genetics of Aging. Cold Spring Harbor Laboratory, New York, New York. October 2-6, 2002.

Drissi R, Bockhold C, Wu J, Liu DY, Daw NC, Dome JS. Alternative lengthening of telomeres (ALT) is the predominant mechanism for telomere maintenance in human osteosarcoma. Meeting on the Role of Telomeres and Telomerase in Cancer, AACR Meeting, San Francisco, California. December 7-11, 2002.

Drissi R, Roussel MF, Dome J, Cleveland JL. Human TERT inhibits telomerase activity and delays the immortalization process in murine cells. Meeting on Telomeres and Telomerase, Cold Spring Harbor Laboratory, New York, USA. March 28-April 1, 2001.