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Molecular Cardiovascular Biology

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Shuyun Wang, MD, PhD

Title

Research Fellow, Division of Molecular Cardiovascular Biology

Email

shuyun.wang@cchmc.org

Phone

513-636-2531

Credentials

MD: Shandong Medical University, Jinan, Shandong, China, 1990

Residency: Pediatrics, Jinan Central Hospital, Jinan, Shandong, China, 1990-1996

Attending: Pediatrics, Jinan Central Hospital, Jinan, Shandong, China, 1996-1998

PhD: Shandong University, Jinan, Shandong, China, 1998-2001

Associate Professor: Pathophysiology, Shandong University, Jinan, Shandong, China, 2001-2006 

Position History

  • Residency and attending pediatrician, Jinan Central Hospital, Jinan, Shandong, China, 1990-1998
  • Associate Professor, Department of Pathophysiology, Medical School, Shandong University, China, 2001-2006
  • Research fellow, Division of Molecular Cardiovascular Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2005-present

Research

Pathogenesis of cardiomyopathy; molecular basis of cardiovascular and body patterning defects; mechanisms of microvascular hyperpermiability

Research Grants and Contracts

Determination of cardiac looping: role of Zic3 at the node. AHA postdoctoral fellowship. 2007-2009, PI

Publications, Most Recent

Wang, S.; Ware S.M.: Use of FOXJ1CreER2T mice for inducible deletion of embryonic node gene expression. Genesis, 2009

Ju, Y.; Wang, T; Li, Y; Xin, W; Wang, S (Corresponding author); Li J. Coxsackievirus B3 affects endothelial tight junctions: possible relationship to ZO-1 and F-actin, as well as p38 MAPK activity.Cell Biol Int, 31:1207-1213. 2007.

Guo, XH; Huang, QB; Chen, B; Wang, SY; Li, Q; Zhu, YJ; Hou, FF; Fu, N; Brunk, UT; Zhao, M. : Advanced glycation end products induce actin rearrangement and subsequent hyperpermeability in endothelial cells.APMIS, 114: 874–883. 2006.

Fellows