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Section of Neonatology, Perinatal and Pulmonary Biology

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Tanya V. Kalin, MD, PhD.

Tanya V. Kalin, MD, PhD

Title

Assistant Professor of Pediatrics

Appointment

Assistant Professor, University of Cincinnati College of Medicine

Email

tatiana.kalin@cchmc.org

Phone

513-803-1201

Fax

513-636-2423

Credentials

MD: Russian Medical Academy, Moscow, Russia 1992 - Medicine

PhD: Institute of Immunology, Moscow, Russia: 1997 - Immunology

Position History

1997 - 2000 Postdoctoral Fellow, Department of Biochemistry and Molecular Biology, College of Medicine, University of Illinois at Chicago, Chicago, IL. Effects of anticancer drugs on the acquisition of anti-tumor immunity.

2001 - 2004 Study Director/Laboratory Supervisor, Toxicology Research Laboratory Inc., Chicago, IL. NIH-funded preclinical studies using anticancer drugs and animal models of cancer.

2004 – 2006 Postdoctoral Fellow, Department of Molecular Genetics, College of Medicine, University of Illinois at Chicago, Chicago, IL.

2007 – present Assistant Professor of Pediatrics, Neonatology and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH. Role of Foxm1 transcription factor in lung and prostate cancer.

Awards and Honors

  • 2009 – 2012 Research Grant from Department of Defense
    Role of Foxm1 Protein in Initiation and Progression of Prostate Cancer.
  • 2008 – 2009 Award from American Cancer Society (ACS), Ohio Division, Inc.
    Role of Foxm1 Protein in Initiation and Progression of Lung Cancer.
  • 2008 – 2010 Grant from Concern Foundation
    Foxm1 Protein in Inflammation During Formation of Lung Cancer.
  • 2008 American Cancer Society Institutional Research Grant
    Role of Foxm1 Protein in Macrophages.
  • 1999-2002 Clinical Cytometry Society Award for Cell imaging and Cell analisys Research.
  • 1996-1997 Fellowship from European Soros Foundation.
  • 1997 Award from the International Immunology Society, 9th International Immunology Congress, San Francisco, USA.
  • 1996 Fellowship from the European Immunology Society.

Research

Transcriptional regulation of DNA replication and mitosis in tumor cells in vitro and in vivo; diagnostic, prevention and treatment of lung and prostate cancers.  

Publications, Most Recent

Wang I-C, Meliton L., Tretiakova M., Kalinichenko V.V., and Kalin T.V. (2008). Transgenic Expression of the Forkhead Box M1 Transcription Factor Induces Formation of Lung Tumors. Oncogene. Jul 10; 27(30):4137-49.

Kalin T.V., Wang IC, Meliton L, Zhang Y, Wert SE, Ren X, Snyder J, Bell SM, Graf L Jr, Whitsett JA, Kalinichenko VV. (2008). Forkhead Box m1 transcription factor is required for perinatal lung function.Proc Natl Acad Sci USA. Dec 9;105(49):19330-5.

Kalin T.V., Meliton L., Meliton A.Y., Zhu X., Whitsett J.A., and Kalinichenko V.V. (2008). Pulmonary Mastocytosis and Enhanced Lung Inflammation in Mice Heterozygous Null for the Foxf1 Gene. Am J Respir Cell Mol Biol. Oct; 39(4):390-9.

Malin, D., T. V. Kalin, E. Boetticher, X. Zhu and V. V. Kalinichenko (2007). Forkhead box F1 is essential for migration of mesenchymal cells and directly induces integrin-beta3 expression. Molecular and Cellular Biology. Apr; 27(7):2486-98.

Ramakrishna S., Kim I-M, Petrovic V., Wang I-C., Malin D., T. V. Kalin, , Zhao Y-Y, Ackerson T., Qin Y., Malik A.B., Costa R.H., and Kalinichenko V.V. (2007). Myocardium defects and ventricular hypoplasia in mice homozygous null for the Forkhead Box M1 transcription factor. Developmental Dynamics. Apr; 236(4):1000-13.

Kim, I-M., T. Ackerson, S. Ramakrishna, M. Tretiakova, I-C. Wang, T. V. Kalin, M. L. Major, H. M. Yoder, R. H. Costa, and V. V. Kalinichenko. (2006). The Forkhead Box m1 Transcription Factor Stimulates the Proliferation of Tumor Cells during Development of Lung Cancer. Cancer Research. 66 (4): 2153-2161.

Kalin T. V., I. C. Wang, T. J. Ackerson, M. L. Major, C. J. Detrisac, V. V. Kalinichenko, A. Lyubimov, and R. H. Costa (2006). Increased Levels of the FoxM1 Transcription Factor Accelerate Development and Progression of Prostate Carcinomas in both TRAMP and LADY Transgenic Mice. Cancer Research. 66(3): 1712-1720.

Professional Organization Memberships

  • AACR- American Association for Cancer Research
  • AHA - American Heart Association
  • WFA - Women Faculty Association

Faculty