Bin Huang, PhD
Title
Biostatistician
Appointment
Assistant Professor, University of Cincinnati College of Medicine
Email
bin.huang@cchmc.org
Phone
513-636-6712
Credentials
BS: Shanghai Jiao Tong University, Shanghai, China, 1991.
MS: University of Cincinnati, Cincinnati, Ohio, 1995.
PhD: Environmental Health, University of Cincinnati, Cincinnati, OH, 2002.
Awards and Honors
- National Science Foundation (NSF) Travel Award, ENAR Junior Investigator Workshop, Tampa, FL, Mar 2005
- National Science Foundation (NSF) Travel Award for Young Women Researcher, Pathways in the Future, Toronto, ON, Canada, Aug 2004
- The best abstract (Co-Author) presented to North American Society for Pediatric and Adolescent Gynecology (NASPAG), La Jolla, CA, May 2004
- Comer-Reynolds Memorial Statistical Award for outstanding graduation student, 2002
Research
Application motivated statistics devleopment include statistical modeling of mediation or surrogacy effect, censored outcome and measurement errors, statistics evaluation of gene by environment interaction, and Bayesian methods. Areas of application are primarily in pubertal developmental research such as hormone and psychosocial behavioral linkage, and modeling/evaluation of pubertal maturational process, prevention/intervention studies such as breast cancer and STD testing, HPV vaccine research, and juvenial rhemotoid/idiopathic arthrits research.
Research Grants and Contracts
1R01DA019965-01A1 (Huang)
04/10/06 - 12/31/09
NIH/NIDA (R01)
Innovative Modeling of Puberty and Substance Use Risk
The goals of this study are two folds. It is aimed to testing direct and indirect of the pubertal transitional process to the early development of substance abuse. The aim accomplished by investigates two new statistical methods in modeling pubertal transition and mediational process where latent variables are involved.
Role: Principal Investigator
1R01DA016402-01 (Dorn)
04/15/03 - 03/31/08
NIH/NINR
Smoking and Metabolic Complications in Adolescent Girls
Goal: To examine the combined impact of smoking, depression and anxiety, on timing of puberty, bone and reproductive health.
Role: Co-Investigator
5R01NR007615-04 (Dorn)
10/01/03 - 06/30/08
NIH/NINR(R01)
Endocrine Changes and Treatment of Conduct Problems
Goal: To examine hormonal changes and its interaction with the treatment in young patients after a brief booster treatment on disruptive behavior disorders.
Role: Co-Investigator
1U01ES012770-010002 (Biro)
09/01/03 - 08/31/10
NIH/NCI (U01)
Puberty and Cancer Initiation: Environment, Diet and Obesity
Goal: To investigate the association of the dietary fatty acid and phytoestrogen composition during the perinatal period and childhood with puberty maturation, and to address environmental factors that impact breast cancer risk.
Role: Co-Investigator
1R01AR049762-01A2 (Wallace)
07/01/06 - 06/30/11
NIH/NIAMS(R01)
Early Aggressive Therapy in Polyarticular JIA (TREAT-JIA)
To examine the effectiveness of an early aggressive therapy in polyarticular JIA patients.
Role: Statistician
FD-R-003435-01 (Hashkes PI; Lovell subcontract PI)
11/01/07 - 10/31/10
FDA/OPD
IL-1 Trap for treatment of familial Mediterranean fever (FMF)
This is a Multi-centered, prospective, randomized alternating treatments single- subject design, double-blind, two arm, comparator clinical trial, that is designed to assess the efficacy of IL-1 Trap in decreasing the number of acute FMF episodes in this 3 years trail.
Role: Co-Investigator
1R01 AI070755-01 (Kahn)
12/01/07 - 11/31/12
NIH/NIAID
Behavioral and Virologic Impact of HPV Immunization
The goal of this study is to characterize the effect of type-specific vaccination on the occurrence of risky sexual behaviors, beliefs about Pap screening, and subsequent distribution of HPV types in adolescents.
Role: Co-Investigator
P60 AR47784 (Giannini)
08/18/08 - 07/31/13
NIH/NIAMS
“Multidisciplinary Clinical Research Center in Cincinnati" Methodology Core
The goal of the project is to provide methodological support to the Multidisciplinary Clinical Research Center in Cincinnati.
Role: Principal Biostatistician
P60 AR47784 (Seid)
08/18/08 - 07/31/13
NIH/NIAMS
Determinants of Health-Related Quality of Life in Children with JIA
The goal of the project is to determine the extent to which biologic and physiologic/laboratory variables, clinical and functional status, and health perceptions predict HRQOL in children with JIA and to determine the degree to which specific individual, family and environmental characteristics moderate this relationship.
Role: Co-Investigator
Professional Organization Memberships
Special Interests
Biostatistics, Puberty, Substance Use/Abuse, STI, GE interaction and QOL
Selected Publications
Kahn JA, Ding L, Huang B, et al. Mother’s Intention for Their Daughters and Themselves to Receive the Human Papillomavirus Vaccine: A National Study of Nurses.Pediatrics 2008, in press.
Dorn LD, Susman EJ, Pabst SR, Huang B, et al. The association of Depressive Symptoms and Anxiety with Bone Health in Ever Smoking and Never Smoking Adolescent Girls.Arch Pediatr Adolesc Med 2008, in press.
Biro FM, Huang B, Daniels SR, Lucky AW. Pubarche as well as Thelarche May be a Marker for the Onset of Puberty. Journal of Pediatric and Adolescent Gynecology 2008, in press
Dorn LD, Huang B, et al. Differences in Endocrine Parameters and Psychopathology in Girls.JPEM 2008, in press.
Kahn JA, Huang B et al. Patterns and Determinants of Physical Activity in US Adolescents.Journal of Adolescent Health 2008;42(4):369-77.
Kahn JA, Rosenthal SL, Yan J, Huang B, et al. Rates of HPV Vaccination, Attitudes about Vaccination, and HPV Prevalence Post-Licensing in Young Women.Obstetrics & Gynecology 2008;111(5):1103-10.
Mahabee-Gittens ME, Huang B, Slap G, Gordon J. An Emergency Department Intervention to Increase Parent-Child Tobacco Communication.Journal of Child and Adolescent Substance Abuse 2008;17(2):71-83.
Goodman E, Huang B, Schafer-Kalhoff T, Adler NE. Perceived Social Status: A New Type of Identify which Influences Adolescents’ Self Rated Health.Journal of Adolescent Health 2007;41(5):479-87.
Lovell DJ, et al. A Randomized Controlled Trial of Calcium Supplementation to Increase Bone Mineral Density in Children with Juvenile Rheumatoid Arthritis.Arthritis and Rheumatism 2006;54(7):2235-42.
Wallace CA, Ravelli A, Huang B, Giannini EH, et al. Preliminary validation of clinical remission criteria using the OMERACT filter for select categories of juvenile idiopathic arthritis.Arthritis and Rheumatism 2006;33(4):789-95
Huang BF, et al. Pubertal correlates in Black and white girls.Journal of Pediatrics 2006;148(2):234-40.
Wallace CA, Huang B, Bandeira M, Ravelli A, Giannini EH. Patterns of Clinical Remission in Select Categories of Juvenile Idiopathic Arthritis (JIA).Arthritis and Rheumatism 2005;52(11):3554-62.
Kahn JA, Bernstein DI, Rosenthal SL, Huang B, Kollar LM, Colyer JL, Tissot AM, Hillard PA, Witte D, Groen P, Slap GB. Acceptability of human papillomavirus self testing in female adolescents.Sex Transmitted Infect 2005;81(5):408-14.
Goodman E, McEwen BS, Huang B, Dolan LM, Adler NE. Social inequalities in biomarkers of cardiovascular risk in adolescence.Psychosomatic Medicine 2005;67(1):9-15.
Peng, Y, Huang B, Frank B, Feng L, Guo, Z, Slap G. Outcome of low birth weight in China: A 16-year longitudinal study.Acta Paediatrica 2005;94:843-9.
Huang B, Sivaganasen S, Succop P, Goodman E. Statistical assessment of mediational effects for logistic mediational models.Statistics in Medicine 2004;23(17):2713-28.
Goodman E, Daniels SR, Morrison JA, Huang B, Dolan LM. Contrasting prevalence of and demographic disparities in the WHO and NCEP definitions of metabolic syndrome among adolescents.The Journal of Pediatrics 2004;145(4):445-51.
Kahn JA, Huang B, Austin B, Aweh G, Colditz G, Frazier L. Development of a scale to measure adolescents' beliefs and attitudes about postponing sexual initiation.J Adolescent Health 2004;35:425e1-425e10.
Goodman E, Huang B, Wade T, Kahn R. A Multilevel analysis of the relationship of socioeconomic status to adolescent depressive symptoms: does school context matter?The Journal of Pediatrics 2003;143(4):451-6.
Goodman E, Slap G,Huang B. Quantifying the Public Health Impact of Socioeconomic Status on Adolescent Depression and Obesity.AJPH 2003;V93:1844-50.
Goodman E, Huang B. Socioeconomic status, depressive symptoms, and adolescent substance use.Arch Pediatr Adolesc Med 2002;156:448-53.
Goodman E, Huang B. Socioeconomic status, and health service utilization among adolescent women.Women’s Health Issues 2001;11(5):416-26.
Slap GB, Goodman E, Huang B. Adoption as a Risk Factor for Suicidal Behavior during Adolescence.Pediatrics 2001;108(2):e30.
Selected Presentations
Ding L, Huang B, Sivaganisan S. Bayesian Mixture Modeling for Interval Censored Age Onset of Puberty. The Joint American Statistical Association Meeting, Denver, CO, August 3-7, 2008.
Huang B. Evaluate Gene by Environmental interaction for Case-Control Studies: Relaxing rare disease and independence assumptions. The Joint American Statistical Association Meeting, Denver, CO, August 3-7, 2008.
Huang B. Mediation Analyses for Categorical Outcomes: casual mediation effect and graphic presentation. Society for Prevention Research, May 26-30, 2008.
Kahn J, Huang, B, Ding, L, Frazier L. Impact of Maternal Communication About Skin, Cervical and Lung Cancer Prevention on Adolescent Prevention Behaviors. 2008 SAM Annual Meeting, Greensboro, NC, Mar 26-29, 2008.
Biro F, Huang, B, Denials S. BMI changes during teen years in girls are influenced by BMI at age 9. 2008 SAM Annual Meeting, Greensboro, NC, Mar 26-29, 2008.
Huang B, Ding, L, Biro FM, Dorn LD, Susman EJ. Mapping Maturational Stage to Serum Sex Hormones and Testicular Volume: Comparison of Three Types of Raters. 2008 SRA Biennial Meeting, Chicago, Mar 6-9, 2008.
Huang J, Huang B. Proportion of Treatment Effects Explained by a Continuous Surrogate Marker in Randomized Clinical Trial. The Joint American Statistical Association Meeting, Salt Lack City, UT, July 29 – Aug 2, 2007.
Huang B, Dorn LD, Biro FM, Susman E. Misclassification in Tanner Stage: Its Implication for pubertal timing and what we can do about it. Society for Research in Child Development (SRCD), Boston, MA. Mar 29-Apr 1, 2007.
Huang B. Bayesian Probability Matching Prior for attributable risk interval estimation. The Joint American Statistical Association Meeting, Seattle, WA, August 6-10, 2006.
Biro FM, Huang B, Lucky AW. Gonadarche and Pubarche in girls: What represents the onset of puberty? North American Society for Pediatric and Adolescent Gynecology (NASPAG).
Goodman E, Huang B, Schafer-Kalkhoff T, Adler NE. Developmental changes in perceived social status. The Pediatric Academic Societies Annual Meeting, San Francisco, CA Apr 29 - May2, 2006.
Goodman E, Huang B, Schafer-Kalkhoff T, Adler NE. Developmental trajectories in perceived social status. Presented to The Society for Adolescent Medicine, Boston, MA, March 24-28, 2006.
Huang B, Sivaganasen S. A Case Study on Bayesian Confirmatory Factor Analysis to Ordinal Scaled Measures with Small Sample. The 8th Biannual Bayesian Case Study Statistics Workshop, September 15-17, 2005.
Huang B, Sivaganasen S, Goodman E, Slap, G. Marginally Least Informative Prior for attributable risk interval estimation. The Joint American Statistial Association Meeting, Toronto, Canada, August 6-13, 2003.
Biro F. Huang B et. al. Impacts of the Interval Between Onset of Puberty and Menarche? North American Society for Pediatric and Adolescent Gynecology (NASPAG), New Orleans, May 19-21, 2005
Huang B, Sivaganasen S, Goodman E, Slap, G. Marginally Least Informative Prior for attributable risk interval estimation. The Joint American Statistial Association Meeting, Toronto, Canada, August 6-13, 2003.
Huang B, Slap G. Complementary and alternative medicine Use by U.S. adolescents. The Society for Adolescent Medicine, St. Louis, Missouri, March 24-28, 2004
Huang B, Sivaganasen S, Goodman E, Slap, G. Confidence interval estimation of attributable risk. The Joint American Statistial Association Meeting, San Fransisco, August 3-10, 2003.
Huang B, Slap G. A Chinese 16-year Longitudinal Study on Physical Growth and Neurodevelopment of Low Birth Weight Infants. Children’s Hospital International Health Conference, Cincinnati, OH, Apr. 16, 2003
Huang B, Sivaganasen S, Succop P, Goodman E. Statistical Assessment of Mediaitonal Effects for Generalized Mediational Models. The Joint American Statistical Association Meeting, New York, August 11-15, 2002.
Huang B. Statistical Assessment of the Contribution of a Mediator ot an Exposure Outcome Process. Seminar of Biostatistics, Dept. of Environmental Health, Jan 2002.
Huang B, Sivaganesan S, Succop P, Goodman E. Estimation of Mediation Effects in Health Science via Bayesian Methods. Joint Statistics Society Meeting, Atlanta, GA, August 2001.
Related Areas
This person works in these other areas at Cincinnati Children's Hospital Medical
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