Kris A. Steinbrecher, PhD
Appointment
Assistant Professor of Pediatrics, University of Cincinnati College of Medicine
Phone
513-636-4415
Fax
513-636-5581
Credentials
PhD: Molecular and Developmental Biology, University of Cincinnati, Cincinnati, OH, 2001.
Postdoctoral Fellowship: Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, 2001-2005.
Awards and Honors
Poster of Distinction, Digestive Disease Week, 1998
Poster of Distinction, World Congress of Pediatric Gastroenterology and Nutrition, 2000
Gastroenterology Research Group / American Gastroenterological Association Fellow Travel Award, 2002
Lineberger Comprehensive Cancer Center Postdoctoral Fellowship, 2002
Crohn's and Colitis Foundation of America Postdoctoral Fellowship, 2003
American Cancer Society Postdoctoral Fellowship, 2003 - 2005
Trustee Award, Cincinnati Children's Hospital Research Foundation, 2005 – 2007
Research Scholar Award, American Gastroenterological Association (AGA)/FDHN Foundation, 2007
Career Development Award, Crohn's and Colitis Foundation of America, 2007
Publications, Most Recent
Steinbrecher, K.A.; Rudolph, J.A.; Luo, G.; Cohen, M.B.: Coordinate upregulation of guanylin and uroguanylin expression by hypertonicity in HT29-18-N2 cells. American Journal of Physiology: Cell Physiology, 2002; 283: C1729-37.
Steinbrecher, K.A.; Wowk, S.; Rudolph, J.A.; Witte, D.P.; Cohen, MB.: Targeted Inactivation of the Mouse Guanylin Gene Results in Increased Proliferation of Colonic Epithelia. American Journal of Pathology, 2002; 161:2169-2178.
Anest, V.; Hanson, J.L.; Cogswell, P.C.; Steinbrecher, K.A.; Strahl, B.D.; Baldwin, A.S.: A Nucleosomal Function for IκB kinase-α in NF-κB-Dependent Gene Expression.Nature, 2003; 423:659-663.
Mann, E.A.; Steinbrecher, K.A.; Stroup, C.; Witte, D.P.; Cohen, M.B.; Giannella, R.A.: Lack of Guanylyl Cyclase C, the Receptor for Escherichia coli Heat-stable Enterotoxin, Results in Reduced Polyp Formation and Increased Apoptosis in the multiple intestinal neoplasia (Min) Mouse Model. International Journal of Cancer, 2005; 116:500-5.
Steinbrecher, K.A.; Wilson, W.; Cogswell, P.C.; Baldwin, A.S.: Glycogen Synthase Kinase 3β Functions To Specify Gene-Specific, NF-κB-Dependent Transcription. Molecular and Cellular Biology, 2005: 25(19):1-12.
Professional Organization Memberships
American Gastroenterological Association
North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition
Crohn's and Colitis Foundation of America
Special Interests
Presentations, Most Recent
Guanylin, uroguanylin and guanylate cyclase C: Regulation in a mouse model of osmotic diarrhea. Experimental Biology; May 1999; Washington, DC.
Serine / threonine protein kinase pathways regulate the induction of guanylin and uroguanylin during osmotic stress. Digestive Disease Week; May 2002; San Francisco, CA.
Targeted inactivation of guanylin results in increased proliferation in mouse colonic crypts. Digestive Disease Week; May 2002; San Francisco, CA.
Regulation of NF-κB Activity by Glycogen Synthase Kinase 3β. Keystone Symposia; January 2004; Snowbird, UT.
Role of GSK3β in NF-κB–dependent gene expression. Lineberger Comprehensive Cancer Center, February 2004; UNC-Chapel Hill.
Related Areas
This person works in these other areas at Cincinnati Children's Hospital Medical
Center:
