Clinical Pharmacology

Shannon N. Saldaña, PharmD, MS, BCPP

Title

Instructor, Department of Pediatrics, Divisions of Clinical Pharmacology and Pharmacy.

Appointment

Assistant Professor, University of Cincinnati College of Medicine

Email

shannon.saldana@cchmc.org

Phone

513-636-3012

Fax

513-636-1657

Credentials

PharmD: Purdue University, West Lafayette, IN, 2003.

MS: The University of Texas, Austin, TX, 2005.

Residency: Psychiatric Pharmacy, The University of Texas and The University of Texas Health Science Center, San Antonio, TX.

Certification: Psychiatric Pharmacy, 2005.

Position History

2005-present: Pharmacy Clinical Specialist, Psychiatry, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio.

2006-present: Adjunct Assistant Professor of Clinical Pharmacy, The James L. Winkle College of Pharmacy; University of Cincinnati, Cincinnati, Ohio.

Research

Genetic contributions of medication response (efficacy and toxicity).

Research Grants and Contracts

CYP2D6 Pharmacogenetics in Risperidone-Treated Children and Adolescents with Psychiatric or Neurodevelopmental Disorders. Translational Research Initiative (TRI), Cincinnati Children’s Research Foundation. Principal Investigator.
July 1, 2008 - June 30, 2009.

Centers for Education and Research in Therapeutics (CERTs): The impact of pharmacogenetic testing on the treatment of children with risperidone. Agency for Healthcare Research and Quality (AHRQ). Co-Investigator. Spetmeber 1, 2007 - October 31, 2008.

Pediatric Pharmacology Research Unit (PPRU). NIH/NICHD Renewal. Co-Investigator. August 8, 2005 - December 31, 2009.

Publications, Most Recent

Prows CA, Nick TG, Saldaña SN, Pathak S, Liu C, Zhang K, Daniels Z, Vinks AA, Glauser TA. Drug Metabolizing Enzyme Genotypes and Aggressive Behavior Treatment Response In Hospitalized Pediatric Psychiatric Patients. J Child Adolesc Psychopharmacol In press.

Prows CA, Saldaña SN. Nurses' genetic / genomics competencies when medication therapy is guided by pharmacogenetic testing: children with mental health disorders as an exemplar.J Pediatr Nurs In press.

Nick TG, Saldaña SN. Pharmacogenetics and pharmacogenomics: Statistical challenges in design and analysis.CHANCE 2009;22:56-62.

Saldaña SN. Book Review: Handbook of Child and Adolescent Psychopharmacology. J Pediatr Pharmacol Ther 2007;12:129-130.

Delgado SV, Saldaña SN, Barzman DH, Coffey B. Response to Duloxetine in a Depressed, Treatment-Resistant Adolescent Female.J Child Adolesc Psychopharmacol 2007;17:889-894. PMID: 18315460

Saldaña SN, Delgado SV. Ziprasidone-induced galactorrhea in an adolescent female.J Child Adolesc Psychopharmacol 2007;17:259-60. PMID: 17489723

Jiang Z, Dragin N, Martin MV, Guengerich FP, Akillu E, Ingelman-Sundberg M, Kadlubar FF, Saldaña SN, Sorter M, Vinks AA, von Richter O, Jin L, Nebert DW. Search for an association between the human CYP1A2 genotype and CYP1A2 enzyme phenotype. Pharmacogenet Genomics 2006;16:359-367. PMID: 16609368

Saldaña SN, Barker EL. Temperature and 3,4-methylenedioxymethamphetamine alter human serotonin transporter-mediated dopamine uptake.Neurosci Lett 2004; 354:209-212. PMID: 14700733

Roman DL, Saldaña SN, Nichols DE, Carroll FI, Barker EL, Distinct recognition of psychostimulants by human serotonin transporters.J Pharmacol Exp Ther 2004; 308(2):679-687. PMID: 14593087

Presentations, Most Recent

Pharmacogenomics in personalized medicine. Oral Presentation. Meeting: “Early detection and disease prevention: a case based approach to personalized medicine,” Alexian Brothers Medical Center, Elk Grove Village, Illinois. September, 2007.

Implementation of pharmacogenetic testing at Cincinnati Children's: tailoring psychiatric therapy to better suit patient needs. Oral Presentation Meeting: “Pediatric Hot Topics,” St. Vincent Women’s Hospital, Indianapolis, Indiana. May, 2006.

Professional Organization Memberships

2002-present Member, College of Psychiatric and Neurologic Pharmacists
2003-present Reviewer, The Annals of Pharmacotherapy
2004-present Member, American Pharmacists Association
2004-present Member, American Society of Health-System Pharmacists
2004-present Member, National Alliance for the Mentally Ill
2006-present Member, American Society of Clinical Pharmacology and Therapeutics
2006-present Reviewer, Clinical Pharmacology and Therapeutics
2007-present Research Committee, College of Psychiatric and Neurologic Pharmacists; Vice Chair 2008-2009
2007-present Abstract and poster reviewer for College of Psychiatric and Neurologic Pharmacists annual meeting
2007-present Member, American Association for Clinical Chemistry
2007-present National Marrow Donor Program member
2007-present Pharmacy Divisional Scientific Review Committee Chair, Cincinnati Children’s Hospital Medical Center.
2007-2008 Pharmacy Shared Governance Performance Improvement / Research Committee Chair, Cincinnati Children’s Hospital Medical Center.
2008 Reviewer, Personalized Medicine
2008 Reviewer, Journal of Child and Adolescent Psychopharmacology
2008 Reviewer, Journal of Pediatrics
2008-present Pharmacist volunteer, Drop Inn shelter, Cincinnati, Ohio
2008-present GoGreen team member, Cincinnati Children’s Hospital Medical Center
2008-2009 Pharmacy Coordinating Council Member and Chair-Elect, Cincinnati Children’s Hospital Medical Center
2008-2009 Abstract Review Committee Member, College of Psychiatric and Neurologic Pharmacists
2008-2009 Research Resources Subcommittee Chair, College of Psychiatric and Neurologic Pharmacists
2009 March for Babies walk captain, March of Dimes, Cincinnati, Ohio