Jules Rosen
My research interests involve studying the altered morphology present in the hippocampi of the epileptic brain. To this end I use a variety of techniques, including immunohistochemistry, genetic manipulation of target genes and confocal microscopy. My current focus is the Pten knockout model of epilepsy. This model allows us to alter brain structure and function at specific time points during development, leading to epileptiform activity. By examining the structural and functional changes thought to cause seizures, novel treatments could be developed to prevent or reverse these changes.
