Anne Boat, MD
Staff Anesthesiologist
Academic Information
Assistant Professor, Division of Pediatric Anesthesia
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Specialties
Fetal surgery; liver transplantation
Education and Training
MD: University of North Carolina School of Medicine, Chapel Hill, NC. Residency: Anesthesia and OB-GYN, University Hospital, Cincinnati, OH. Fellowship: Pediatric Clinical Anesthesia, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
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Vidya Chidambaran, MD
Anesthesiologist
is an anesthesiologist and acute pain physician with interests in evaluating pharmacogenetics, pharmacokinetics and pharmacodynamics of anesthetics and analgesics by clinical studies. She is presently a PI / Co-PI in pharmacogenetic studies of opioids in post - spine surgical patients and propofol in morbidly obese adolescents. She has a special interest in developing personalized pediatric analgesia, based on genotype-phenotype associations.
Vidya Chidambaran, MD
Anesthesiologist
Academic Information
Assistant Professor, Division of Pediatric Anesthesia
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Specialties
Clinical InterestsPediatric anesthesia Research InterestsPharmacogenetics; spine infection
Education and Training
MBBS: Medicine,Bangalore Medical College, India, 1997 MD: Anesthesiology, Kasturba Medical College, India, 1998-2001 Internship: Anesthesiology, Jackson Memorial Hospital, Miami, Florida, 2003-2004 Residency: Anesthesiology, Brookdale University Hospital, Brooklyn, New York, 2004-2007 Fellowship: Pediatric Anesthesia, Johns Hopkins Hospital, Baltimore, Maryland, 2007-2008
Publications
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Steve C. Danzer, PhD
is a developmental neurobiologist with a research program examining the role of adult-generated hippocampal granule cells in the development of epilepsy. Research on the impact of granule cells in autism is a second lab focus. Techniques used include models of epilepsy and autism, confocal microscopy, electrophysiology, immunohistochemistry, organotypic slice culture, and genetic manipulations of target genes. Visit the Danzer Lab.
513-636-4526
steve.danzer@cchmc.org
Steve C. Danzer, PhD
Academic Information
Associate Professor, Division of Pediatric Anesthesia
Associate Professor, Division of Neurobiology
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Specialties
Education and Training
PhD: University of Arizona, Tucson, Arizona.
Postdoctoral Research: Duke University, Durham, NC.
Publications
View PubMed Publications
Pun RYK, Rolle IJ, LaSarge CL, Hosford BE, Rosen JM, Uhl JD, Schmeltzer SN, Faulkner C, Bronson SL, Murphy BL, Richards DA, Holland KD, SC Danzer. Excessive Activation of mTOR in Postnatally Generated Granule Cells Is Sufficient to Cause Epilepsy. Neuron. 2012;75(6):1022-34. Castro OW, Santos VR, Pun RYK, McKlveen JM, Batie M, Holland KD, Gardner M, Garcia-Cairasco N, Herman JP, SC Danzer. Impact of corticosterone treatment on spontaneous seizure frequency and epileptiform activity in mice with chronic epilepsy. PLoS One. 2012;7(9):e46044. Murphy BL, Hofacer RD, Faulkner CN, Loepke AW and SC Danzer. Abnormalities of granule cell dendritic structure are a prominent feature of the intrahippocampal kainic acid model of epilepsy despite reduced post-injury neurogenesis. Epilepsia. 2012;53 (5):908-921. Danzer SC. Depression, stress, epilepsy and adult neurogenesis. Experimental Neurology. 2012;233(1):22-32. Santos VR, Wagner de Castro O, Pun RYK, Hester MS, Murphy BL, Loepke AW, Garcia-Cairasco N and SC Danzer. Contributions of mature granule cells to structural plasticity in temporal lobe epilepsy. Neuroscience. 2011;197:348-57. Murphy BL and SC Danzer. Somatic translocation: a novel mechanism of granule cell dendritic dysmorphogenesis and dispersion. Journal of Neuroscience. 2011;31(8):2959-64. Murphy BL, Pun RY, Yin H, Faulkner CR, Loepke AW and SC Danzer. Heterogeneous integration of adult-generated granule cells into the epileptic brain. Journal of Neuroscience. 2011;31(1):105-17. McAuliffe JJ, Bronson SL, Hester MS, Murphy BL, Dahlquist-Topalá R, Richards DA and SC Danzer. Altered patterning of dentate granule cell mossy fiber inputs onto CA3 pyramidal cells in limbic epilepsy. Hippocampus. 2011 Jan;21(1):93-107. Danzer SC. Postnatal and adult neurogenesis in the development of human disease. Neuroscientist. ct;14(5):446-58. Review. 2008. Walter C, Murphy BL, Pun RYK, Spieles-Engemann AL and SC Danzer. Pilocarpine-induced seizures cause selective time-dependent changes to adult-generated hippocampal dentate granule cells. Journal of Neuroscience. 2007 Jul;27(28):7541-52.
Grants
Contributions of aberrant granule cell integration to the development of epilepsy. Principal Investigator. National Institute of Health. 2009-14. 1R01-NS-062806. Selective disruption of hippocampal dentate granule cells in autism: impact of PTEN deletion. Principal Investigator. National Institute of Health. 2009-14. #1R01-NS-065020-01.
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Kenneth R. Goldschneider, MD, FAAP
Director, Division of Pain Management
is interested in chronic pain in children and young adults. He is involved in several long-term studies of pain in children as well as in developing evidence-based pain care guidelines for epidermolysis bullosa. He is a founding member of the Pediatric Research Network for Pain (PRN-Pain), a collaborative organization of North American pediatric institutions dedicated to working in coordination with government and industry entities to improve pain research in children.
513-636-7768
kenneth.goldschneider@cchmc.org
Kenneth R. Goldschneider, MD, FAAP
Director, Division of Pain Management
Academic Information
Associate Professor, Division of Pediatric Anesthesia
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Specialties
Clinical InterestsComplex chronic pain conditions in infants, children and young adults, including those related to vascular malformations, epidermolysis bullosa and cancer. Research InterestsOutcomes of pain treatment, with a focus on outpatient, chronic pain management.
Education and Training
MD: University of Connecticut Health Center School of Medicine, Farmington, CT, 1991.
Residency: Pediatrics, Duke University Medical Center, Durham, NC, 1991 - 1994; Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh, PA, 1994-1997.
Fellowship: Pediatric Anesthesia, Children's Hospital of Pittsburgh, Pittsburgh, PA, 1997 - 1998; Pain Management, Longwood Combined Pain Fellowship, The Children's Hospital, Boston, MA, 1998 - 1999.
Certification: American Board of Pediatrics, 1994; American Board of Anesthesiology, 1998; ABA Pain Management, 2000.
Publications
View PubMed Publications
Lynch-Jordan AM, Kashikar-Zuck S, Goldschneider KR. Parent perceptions of adolescent pain expression: the adolescent pain behavior questionnaire. Pain. 2010 Dec;151(3):834-42. Goldschneider K, Lucky AW, Mellerio JE, Palisson F, del Carmen Viñuela Miranda M, Azizkhan RG. Perioperative care of patients with epidermolysis bullosa: proceedings of the 5th international symposium on epidermolysis bullosa, Santiago Chile, December 4-6, 2008. Paediatr Anaesth. 2010 Sep;20(9):797-804. Goldschneider KR, Lucky AW. Pain management in epidermolysis bullosa. Dermatol Clin. 2010 Apr;28(2):273-82, ix. Review. Meyer MJ, Goldschneider KR, Bielefeldt K, Zeltzer L, Lackner J, Keefer L. Functional abdominal pain in adolescence: a biopsychosocial phenomenon. J Pain. 2008 Nov;9(11):984-90. Hosu L, Meyer MJ, Goldschneider KR. Cerebrospinal fluid cutaneous fistula after epidural analgesia in a child. Reg Anesth Pain Med. 2008 Jan-Feb;33(1):74-6. Goldschneider KR, Racadio JM, Weidner NJ. Celiac plexus blockade in children using a three-dimensional fluoroscopic reconstruction technique: case reports. Reg Anesth Pain Med. 2007 Nov-Dec;32(6):510-5. Lynch AM, Kashikar-Zuck S, Goldschneider KR, Jones BA. Sex and age differences in coping styles among children with chronic pain. J Pain Symptom Manage. 2007 Feb;33(2):208-16. Lynch AM, Kashikar-Zuck S, Goldschneider KR, Jones BA. Psychosocial risks for disability in children with chronic back pain. J Pain. 2006 Apr;7(4):244-51. Kashikar-Zuck S, Vaught MH, Goldschneider KR, Graham TB, Miller JC. Depression, coping, and functional disability in juvenile primary fibromyalgia syndrome. J Pain. 2002 Oct;3(5):412-9. Kashikar-Zuck S, Goldschneider KR, Powers SW, Vaught MH, Hershey AD. Depression and functional disability in chronic pediatric pain. Clin J Pain. 2001 Dec;17(4):341-9.
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Joel B. Gunter, MD
Staff Anesthesiologist
Academic Information
Professor, Division of Pediatric Anesthesia
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Specialties
Clinical InterestsAnesthesia for congenital cardiac disease; anesthesia equipment and monitoring Research InterestsAnesthesia equipment and monitoring; regional anesthesia in children; outcomes after anesthesia in children
Education and Training
MD: University of Oklahoma, Oklahoma City, OK, 1982.
Residency: Barnes Hospital, St. Louis, MO, 1985.
Fellowship: Children's Hospital National Medical Center, Washington, DC, 1986.
Certification: Anesthesiology, 1986 (Recertified 2000)
Publications
View PubMed Publications
Hoffmann CO, Samuels PJ, Beckman E, Hein EA, Shackleford TM, Overbey E, Berlin RE, Wang Y, Nick TG, Gunter JB. Insufflation vs intubation during esophagogastroduodenoscopy in children. Paediatr Anaesth. 2010 Sep;20(9):821-30.
Mahmoud M, Radhakrishman R, Gunter J, Sadhasivam S, Schapiro A, McAuliffe J, Kurth D, Wang Y, Nick TG, Donnelly LF. Effect of increasing depth of dexmedetomidine anesthesia on upper airway morphology in children. Paediatr Anaesth. 2010 Jun;20(6):506-15.
Sadhasivam S, Cohen LL, Hosu L, Gorman KL, Wang Y, Nick TG, Jou JF, Samol N, Szabova A, Hagerman N, Hein E, Boat A, Varughese A, Kurth CD, Willging JP, Gunter JB. Real-time assessment of perioperative behaviors in children and parents: development and validation of the perioperative adult child behavioral interaction scale. Anesth Analg. 2010 Apr 1;110(4):1109-15.
Mahmoud M, Gunter J, Donnelly LF, Wang Y, Nick TG, Sadhasivam S. A comparison of dexmedetomidine with propofol for magnetic resonance imaging sleep studies in children. Anesth Analg. 2009 Sep;109(3):745-53.
Mahmoud M, Gunter J, Sadhasivam S. Ciné MRI airway studies in children with sleep apnea: optimal images and anesthetic challenges. Pediatr Radiol. 2009 Oct;39(10):1034-7.
Sadhasivam S, Cohen LL, Szabova A, Varughese A, Kurth CD, Willging P, Wang Y, Nick TG, Gunter J. Real-time assessment of perioperative behaviors and prediction of perioperative outcomes. Anesth Analg. 2009 Mar;108(3):822-6.
Gunter JB, Ball J, Than-Win S. Preparation of the Dräger Fabius anesthesia machine for the malignant-hyperthermia susceptible patient. Anesth Analg. 2008 Dec;107(6):1936-45. Varughese AM, Nick TG, Gunter J, Wang Y, Kurth CD. Factors predictive of poor behavioral compliance during inhaled induction in children. Anesth Analg. 2008 Aug;107(2):413-21. Mahmoud M, Bryan Y, Gunter J, Kreeger RN, Sadhasivam S. Anesthetic implications of undiagnosed late onset central hypoventilation syndrome in a child: from elective tonsillectomy to tracheostomy. Paediatr Anaesth. 2007 Oct;17(10):1001-5. Cohen MB, Gunter JB. How safe is intravenous sedation with midazolam and fentanyl for pediatric gastrointestinal endoscopy? Nat Clin Pract Gastroenterol Hepatol. 2007 Oct;4(10):538-9.
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Nancy S. Hagerman, MD
Academic Information
Assistant Professor, Division of Pediatric Anesthesia
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Education and Training
MD: Wake Forest University, Winston-Salem, NC, 2001.
Internship: Mercy Medical Center, Baltimore, MD, 2002.
Residency: Johns Hopkins Hospital, Baltimore, MD, 2005.
Fellowship: Cincinnati Children's Hospital, Cincinnati, OH, 2007.
Publications
View PubMed Publications
Varughese AM, Hagerman NS, Kurth CD. Quality in pediatric anesthesia. Paediatr Anaesth. 2010 Aug;20(8):684-96. Review.
Sadhasivam S, Cohen LL, Hosu L, Gorman KL, Wang Y, Nick TG, Jou JF, Samol N, Szabova A, Hagerman N, Hein E, Boat A, Varughese A, Kurth CD, Willging JP, Gunter JB. Real-time assessment of perioperative behaviors in children and parents: development and validation of the perioperative adult child behavioral interaction scale. Anesth Analg. 2010 Apr 1;110(4):1109-15. Hagerman NS. Remember That There Are Two "Neos" in Avoiding Common ICU Errors. Marcucci L, Martinez E, Haut E, Slonim A, Suarez J, eds. Lippencott Williams & Wilkens. 2006 Philadelphia. Hagerman NS. Remember That Malignant Hyperthermia May Not Have Hyperthermia in Avoiding Common ICU Errors. Marcucci L, Martinez E, Haut E, Slonim A, Suarez J, eds. Lippencott Williams & Wilkens. 2006 Philadelphia.
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Elizabeth A. Hein, MD
Staff Anesthesiologist
Adjunct Assistant Professor of Clinical Anesthesia and Pediatrics
Academic Information
Division of Pediatric Anesthesia
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Specialties
Anesthesia for airway surgery; ENT anesthesia
Education and Training
MD: Medical College of Ohio, Toledo, OH, 1993.
Internship: The Cleveland Clinic Foundation, Cleveland, OH, 1994.
Residency: Cleveland Clinic Foundation, Cleveland, OH, 1997.
Fellowship: Children's Hospital, Columbus, OH, 1999; Children's Hospital of Pittsburgh, Pittsburgh, PA, 1998.
Certification: Anesthesiology, 1999; PALS, 2007; ACLS, 2008.
Publications
View PubMed Publications
Hoffmann CO, Samuels PJ, Beckman E, Hein EA, Shackleford TM, Overbey E, Berlin RE, Wang Y, Nick TG, Gunter JB. Insufflation vs intubation during esophagogastroduodenoscopy in children. Paediatr Anaesth. 2010 Sep;20(9):821-30.
Sadhasivam S, Cohen LL, Hosu L, Gorman KL, Wang Y, Nick TG, Jou JF, Samol N, Szabova A, Hagerman N, Hein E, Boat A, Varughese A, Kurth CD, Willging JP, Gunter JB. Real-time assessment of perioperative behaviors in children and parents: development and validation of the perioperative adult child behavioral interaction scale. Anesth Analg. 2010 Apr 1;110(4):1109-15.
Hein EA, Rutter MJ. New perspectives in pediatric airway reconstruction. Int Anesthesiol Clin. 2006 Winter;44(1):51-64. Review.
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Clifford O. Hoffmann, MD
Staff Anesthesiologist
Academic Information
Associate Professor, Division of Pediatric Anesthesia
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Specialties
Education and Training
MD: Medical College Of Ohio at Toledo, Toledo, Ohio, 1984.
MSc: University of Cincinnati, Ohio, 1976.
BS: University of Cincinnati, Ohio, 1972.
Internship: Akron General Medical Center, Akron, Ohio, 1985.
Residency: Northeastern Ohio University College of Medicine Canton, Ohio, 1987.
Fellow: Cleveland Clinic Foundation, Cleveland, Ohio, 1988.
Certification: American Board of Anesthesiology, 1995; ACLS 2009; PALS 2009.
Publications
View PubMed Publications
Hoffmann CO, Samuels PJ, Beckman E, Hein EA, Shackleford TM, Overbey E, Berlin RE, Wang Y, Nick TG, Gunter JB. Insufflation vs intubation during esophagogastroduodenoscopy in children. Paediatr Anaesth. 2010 Sep;20(9):821-30.
McConville BJ, Steichen-Asch P, Harris R, Neudorf S, Sambrano J, Lampkin B, Bailey D, Fredrick B, Hoffmann C, Woodman D. Pediatric bone marrow transplants: psychological aspects. Can J Psychiatry. 1990 Dec;35(9):769-75.
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Michael P. Jankowski, PhD
is a neuroscientist with expertise in molecular biology, electrophysiology and neuroanatomy. His basic and translational research program analyzes the molecular mechanisms of musculoskeletal pain and the developmental plasticity of sensory neurons before and after peripheral injury. Specifically, the laboratory focuses on effects of inflammation and ischemia on muscle afferent sensitization, and how neonatal injuries can alter the function of sensory neurons both during development and into adulthood. Visit the Jankowski Lab.
513-803-7966
michael.jankowski@cchmc.org
Michael P. Jankowski, PhD
Academic Information
Assistant Professor, UC Department of Pediatrics
Assistant Professor, Department of Anesthesia / Division of Pain Management
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Specialties
Biography
Dr. Jankowski joined the faculty in the Department of Anesthesia/ Division of Pain Management at Cincinnati Children’s Hospital Medical Center in November of 2011. Previously, he had been awarded both pre-doctoral (2006) and postdoctoral National Research Service Awards (2008) prior to becoming faculty at the University of Pittsburgh. While a member of the Department of Neurobiology at the University of Pittsburgh, he presented several public presentations including one seminar titled, “Interfering with the Molecular Mechanisms of Pain” at the Center for Neuroscience at the University of Pittsburgh’s Annual Retreat in 2009, and another titled, ”Preparation and Delivery of siRNAs to Sensory Neurons” at the International Association for the Study of Pain’s Satellite Symposium: “Nociceptors: New Biology” in Edinburgh, Scotland in 2008. He is currently a member of the Society for Neuroscience, the International Association for the Study of Pain, the Society for Pediatric Anesthesia and the American Pain Society.
Education and Training
MS: Neuroscience, University of Pittsburgh, Pittsburgh, Pa. 2003.
PhD: Neurobiology, University of Pittsburgh, Pittsburgh, Pa. 2006.
Postdoctoral Training: University of Pittsburgh. 2006-2010.
Publications
Jankowski, M.P., Rau, K.K., Soneji, D.J., Anderson, C.E., Molliver, D.C., and Koerber, H.R. Purinergic receptor P2Y1 regulates polymodal C-fiber thermal sensitivity during peripheral inflammation. Pain. 153:410-9. 2012. Li, L., Rutlin, M., Abraira, V., Cassidy, C., Jankowski, M.P., Luo, W., Heintz, N., Koerber, H.R., Woodbury, C.J., and Ginty, D.D. The functional organization of cutaneous low-threshold mechanosensory neurons. Cell. 147: 1615-27. 2011. Molliver, D.C., Rau, K.K., McIlwrath, S.L., Jankowski, M.P., and Koerber, H.R. The ADP receptor P2Y1 is necessary for normal thermal sensitivity in cutaneous polymodal nociceptors. Mol. Pain. 7: 13. 2011. Koerber, H.R., McIlwrath, S.L., Lawson, J.J.., Malin, S.A., Anderson, C.E., Jankowski, M.P., and Davis, B.M. Mouse cutaneous C-fibers lacking TRPV1 are sensitized to heat following peripheral inflammation. Molecular Pain. 6: 58. 2010. Jankowski, M.P., Rau, K.K., Soneji, D.J., Anderson, C.E., and Koerber, H.R. Enhanced artemin/GFRa3 levels regulate mechanically insensitive, heat sensitive C-fiber recruitment after axotomy and regeneration. J. Neurosci. 30: 16272-83. 2010. Rau, K.K., McIlwrath, S.L., Wang, H., Lawson, J.J., Jankowski, M.P., Zylka, M.J., Anderson, D.J., and Koerber, H.R. Mrgprd enhances excitability in specific populations of cutaneous murine polymodal nociceptors. J. Neurosci. 29: 8612-9. 2009. Jankowski, M.P., McIlwrath, S.L., Cornuet, P.K., Jing X, Salerno K.M., Koerber, H.R., and Albers, K.M. Sox11 transcription factor regulates peripheral nerve regeneration in the adult. Brain Res. 1256: 43-54. 2009b. Jankowski, M.P., Lawson, J.J., McIlwrath, S.L., Rau, K.K., Anderson, C.E., Albers, K. M., and Koerber, H.R. Sensitization of cutaneous nociceptors following nerve transection and regeneration: Possible role of target derived neurotrophic factor signaling. J. Neurosci. 29: 1636-47. 2009a. Jankowski, M.P. and Koerber, H.R. Neurotrophic Factors and Nociceptor Sensitization. In Translational Pain Research: From Mice to Men. Eds.: Kruger and Light, CRC Press. 31-50. 2009.
Grants
Molecular mechanisms of musculoskeletal pain. Principal Investigator. Rita Allen Foundation Award In Pain. Peripheral mechanisms of musculoskeletal pain after ischemic tissue injury. Principal Investigator. International Society for the Study of Pain, Early Career Grant.
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Thomas J. Kabalin, MD
Staff Anesthesiologist
Academic Information
Associate Professor, Division of Pediatric Anesthesia
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Specialties
ENT anesthesia; anesthesia for orthopedic surgery
Education and Training
MD: Georgetown University School of Medicine, 1989.
Internship: University of California at Los Angeles, 1990.
Residency: Pediatrics, University of California at Los Angeles, 1992; Anesthesiology, University of Illinois at Chicago, 1994; Pediatric Anesthesiology, University of California at Los Angeles, 1995.
Certifications: American Board of Anesthesiology, October 1998; PALS, 2007; BLS, 2007.
Publications
View PubMed Publications
Mahmoud M, Sadhasivam S, Salisbury S, Nick TG, Schnell B, Sestokas AK, Wiggins C, Samuels P, Kabalin T, McAuliffe J. Susceptibility of transcranial electric motor-evoked potentials to varying targeted blood levels of dexmedetomidine during spine surgery. Anesthesiology. 2010 Jun;112(6):1364-73.
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Michael J. Kibelbek, MD
Anesthesiologist
Academic Information
Associate Professor, Division of Pediatric Anesthesia
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Specialties
Procedural sedation outside the OR; education
Education and Training
MD: Thomas Jefferson University School of Medicine, Philadelphia, PA, 1979.
Residency: Mercy Hospital, Pittsburgh, PA, 1979-1982; Mercy Hospital Pittsburgh, PA, 1982-1984.
Fellowship: Children's Hospital of Philadelphia, 1984-1985.
Certifications: American Board of Pediatrics, 1984; American Board of Anesthesiology, 1985; PALS, 2008; ACLS, 2007.
Publications
View PubMed Publications
Kibelbek MJ. Cable trapped under Dräger Fabius automatic pressure limiting valve causes inability to ventilate. Anesthesiology. 2007 Mar;106(3):639-40; author reply 640. Kibelbek MJ, Schwartz JA, Tenedios G. Stewart smiled. Pediatrics. 1993 May;91(5):1018-9. Kibelbek MJ. Gastric acid aspiration possible during flexible endoscopy without general anesthesia. Am J Dis Child. 1987 Feb;141(2):128-9.
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Rachel A. Koll, MD
Academic Information
Assistant Professor, Division of Pediatric Anesthesia
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Specialties
Pediatric cardiac anesthesia
Education and Training
MD: Creighton
University School of Medicine, Omaha, NE, 2007. Residency: Anesthesia,
University of Utah, Salt Lake City, UT, 2011. Fellowship: Pediatric
Anesthesia, Cincinnati Children’s Hospital, Cincinnati, OH, 2012. Fellowship: Pediatric
Cardiac Anesthesia, Cincinnati
Children’s Hospital, Cincinnati, OH, 2013. Certification: Anesthesiology, 2012.
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Ik Sung Lee, MD
Director, Clinical Operations, Operating Room
Academic Information
Associate Professor, Division of Pediatric Anesthesia
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Specialties
Operating room management
Education and Training
MD: Kyungpook National University, Taegu, Korea, 1968.
Internship: St. Elizabeth Hospital, Youngstown, OH, 1972-1973.
Residency: University of Cincinnati College of Medicine, Cincinnati, OH, 1973-75.
Fellowship: Pediatric Anesthesia, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 1975-76; Pediatric Anesthesiology and Critical Care, Children's Hospital of Philadelphia, Philadelphia, PA, 1976.
Certification: Anesthesiology, 1979; ACLS, 2008.
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Andreas W. Loepke, MD, PhD
Staff Anesthesiologist
is a clinician-scientist studying the effects of anesthetics on the developing brain. He directs a basic science laboratory and coordinates pre-clinical, translational, and clinical research projects to clarify the molecular mechanisms of anesthetics, focusing on their neuroprotective as well as their neurotoxic effects. Dr. Loepke’s clinical focus is on pediatric cardiac anesthesia and single-ventricle physiology. Visit the Loepke Lab.
513-636-4408
Andreas W. Loepke, MD, PhD
Staff Anesthesiologist
Academic Information
Associate Professor, Division of Pediatric Anesthesia
Phone: 513-636-4408
Fax: 513-636-7337
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Specialties
Clinical InterestsNeonatal anesthesia; neonatal cardiac anesthesia; neonatal brain injury related to congenital heart disease; effects of anesthetics on the developing brain Research InterestsNeonatal brain injury and protection Visit the Loepke Lab.
Biography
Andreas W. Loepke, MD, PhD, is a physician-scientist whose professional efforts are divided between basic science research and his clinical staff position as a pediatric cardiac anesthesiologist in the Department of Anesthesia at Cincinnati Children’s Hospital. His areas of expertise comprise the effects of anesthetics on the developing brain as well as the detection, prevention and treatment of neonatal brain damage. After graduating from medical school in his native Germany, Dr. Loepke began training in Anesthesiology, Pain Medicine and Intensive Care in Germany, followed by an internship in General Surgery at Pennsylvania Hospital and a residency in Anesthesiology at Thomas Jefferson University Hospital in Philadelphia, Pa. Following additional training in Pediatric Anesthesia and Pediatric Cardiac Anesthesia at the Children’s Hospital of Philadelphia, he accepted a position as staff anesthesiologist at the Children’s Hospital of Philadelphia and as an assistant professor of Anesthesia at the University of Pennsylvania School of Medicine. Dr. Loepke directs a research laboratory in the Cincinnati Children’s Hospital Research Foundation and chairs the Department of Anesthesia’s Data Safety Monitoring Board. Dr. Loepke is a frequent lecturer on the effects of anesthetics on the developing brain and has received several prominent awards for his research.
Education and Training
MD: University of Dusseldorf, Germany, 1993.
PhD: University of Dusseldorf, Germany, 1995.
Residency: Thomas Jefferson Medical College, Philadelphia, PA, 1999.
Fellowship: Children's Hospital of Philadelphia, Philadelphia, PA, 2000.
Certification: Anesthesiology, 2000.
Maintenance of Certification: Anesthesiology 2010.
Publications
View PubMed Publications
Istaphanous GK, Howard J, Nan X, Hughes EA, McCann JC, McAuliffe JJ, Danzer SC, Loepke AW. Comparison of the Neuroapoptotic Properties of Equipotent Anesthetic Concentrations of Desflurane, Isoflurane, or Sevoflurane in Neonatal Mice. Anesthesiology. 2011 Feb 2 Boat AC, Sadhasivam S, Loepke AW, Kurth CD. Outcome for the extremely premature neonate: how far do we push the edge? Paediatr Anaesth. 2011 Jan 10. Murphy BL, Pun RY, Yin H, Faulkner CR, Loepke AW, Danzer SC. Heterogeneous integration of adult-generated granule cells into the epileptic brain. J Neurosci. 2011 Jan 5;31(1):105-17. Istaphanous GK, Ward CG, Loepke AW. The impact of the perioperative period on neurocognitive development, with a focus on pharmacological concerns. Best Pract Res Clin Anaesthesiol. 2010 Sep;24(3):433-49. Review. Loepke AW. Developmental neurotoxicity of sedatives and anesthetics: a concern for neonatal and pediatric critical care medicine? Pediatr Crit Care Med. 2010 Mar;1 1(2):217-26. Review. McAuliffe JJ, Loepke AW, Miles L, Joseph B, Hughes E, Vorhees CV. Desflurane, isoflurane, and sevoflurane provide limited neuroprotection against neonatal hypoxia-ischemia in a delayed preconditioning paradigm. Anesthesiology. 2009 Sep;111(3):533-46. Istaphanous GK, Loepke AW. General anesthetics and the developing brain. Curr Opin Anaesthesiol. 2009 Jun;22(3):368-73. Review. Kurth CD, McCann JC, Wu J, Miles L, Loepke AW. Cerebral oxygen saturation-time threshold for hypoxic-ischemic injury in piglets. Anesth Analg. 2009 Apr;108(4):1268-77. Danzer SC, He X, Loepke AW, McNamara JO. Structural plasticity of dentate granule cell mossy fibers during the development of limbic epilepsy. Hippocampus. 2010 Jan;20(1):113-24. Loepke AW, Istaphanous GK, McAuliffe JJ 3rd, Miles L, Hughes EA, McCann JC, Harlow KE, Kurth CD, Williams MT, Vorhees CV, Danzer SC. The effects of neonatal isoflurane exposure in mice on brain cell viability, adult behavior, learning, and memory. Anesth Analg. 2009 Jan;108(1):90-104.
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Mohamed A. Mahmoud, MD
Staff Anesthesiologist
is a pediatric anesthesiologist who has clinical research programs in pediatric airway morphology and neuromonitoring. His primary research interest is examining the effect of currently available anesthetic agents on the upper airway morphology in children with history of obstructive sleep apnea. Effect of anesthesia on neuromonitoring modalities is a second clinical research focus.
513-636-4408
mohamed.mahmoud@cchmc.org
Mohamed A. Mahmoud, MD
Staff Anesthesiologist
Academic Information
Assistant Professor, Division of Pediatric Anesthesia
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Specialties
Spinal surgery; dexmedetomidine effects on neuromonitoring
Biography
Mohamed A. Mahmoud, MD, became a pediatric anesthesiologist in 2005. He is interested in anesthesia for orthopedic surgery, spinal surgery, radiology screening, fetal surgery and liver transplantation.
Education and Training
MD: Ain Shams University Medical School, Cairo, Egypt, 1996.
Residency: SUNY Upstate Medical University, Syracuse, NY, 2000-2004.
Fellowship: Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2004-2005.
Certification: Anesthesiology, 2005.
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John J. McAuliffe III, MD, MBA
Research Director
Staff Anesthesiologist
Director, Institute Pediatric Anesthesia
Academic Information
Associate Professor, Division of Pediatric Anesthesia
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Specialties
Clinical InterestsCardiac anesthesia; neonatal anesthesia Research InterestsAnesthesia on the developing brain
Education and Training
MD: McGill University, Montreal, Canada, 1977.
Residency: Anesthesiology, Brigham and Women's Hospital, Boston, MA, 1982-84; Pediatrics, University of Minnesota, Minneapolis, MN, 1981-82; Pediatrics, University of Minnesota, Minneapolis, MN, 1978-79.
Fellowship: Pediatric Anesthesiology, Children's Hospital Medical Center, Boston, MA, 1984-85.
Certification: Pediatrics, 1984; Anesthesiology, 1985.
Publications
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Istaphanous GK, Howard J, Nan X, Hughes EA, McCann JC, McAuliffe JJ, Danzer SC, Loepke AW. Comparison of the Neuroapoptotic Properties of Equipotent Anesthetic Concentrations of Desflurane, Isoflurane, or Sevoflurane in Neonatal Mice. Anesthesiology. 2011 Feb 2. McAuliffe JJ, Bronson SL, Hester MS, Murphy BL, Dahlquist-Topalá R, Richards DA, Danzer SC. Altered patterning of dentate granule cell mossy fiber inputs onto CA3 pyramidal cells in limbic epilepsy. Hippocampus. 2011 Jan;21(1):93-107. McAuliffe JJ, Loepke AW, Miles L, Joseph B, Hughes E, Vorhees CV. Desflurane, isoflurane, and sevoflurane provide limited neuroprotection against neonatal hypoxia-ischemia in a delayed preconditioning paradigm. Anesthesiology. 2009 Sep;111(3):533-46. Loepke AW, Istaphanous GK, McAuliffe JJ 3rd, Miles L, Hughes EA, McCann JC, Harlow KE, Kurth CD, Williams MT, Vorhees CV, Danzer SC. The effects of neonatal isoflurane exposure in mice on brain cell viability, adult behavior, learning, and memory. Anesth Analg. 2009 Jan;108(1):90-104. McAuliffe JJ, Joseph B, Hughes E, Miles L, Vorhees CV. Metallothionein I,II deficient mice do not exhibit significantly worse long-term behavioral outcomes following neonatal hypoxia-ischemia: MT-I,II deficient mice have inherent behavioral impairments. Brain Res. 2008 Jan 23;1190:175-85. McAuliffe JJ, Joseph B, Vorhees CV. Isoflurane-delayed preconditioning reduces immediate mortality and improves striatal function in adult mice after neonatal hypoxia-ischemia. Anesth Analg. 2007 May;104(5):1066-77, tables of contents. Gunter JB, McAuliffe JJ, Beckman EC, Wittkugel EP, Spaeth JP, Varughese AM. A factorial study of ondansetron, metoclopramide, and dexamethasone for emesis prophylaxis after adenotonsillectomy in children. Paediatr Anaesth. 2006 Nov;16(11):1153-65. McAuliffe JJ, Miles L, Vorhees CV. Adult neurological function following neonatal hypoxia-ischemia in a mouse model of the term neonate: water maze performance is dependent on separable cognitive and motor components. Brain Res. 2006 Nov 6;1118(1):208-21. Loepke AW, McCann JC, Kurth CD, McAuliffe JJ. The physiologic effects of isoflurane anesthesia in neonatal mice. Anesth Analg. 2006 Jan;102(1):75-80. Gunter JB, McAuliffe JJ, Gregg T, Weidner NJ, Varughese AM, Sweeney, DM. Continuous epidural butorphanol relieves pruritus associated with epidural morphine infusions in children. Paediatric Anaesthesia. 2000 10(2):167-172.
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Mark Meyer, MD
Anesthesiologist
Academic Information
Assistant Professor, Division of Pediatric Anesthesia
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Specialties
Clinical InterestsPalliative medicine; end of life care; anesthesiology; pain management Research InterestsAnesthesia; pain management
Biography
Mark Meyer, MD, is a board-certified anesthesiologist who completed his residency at the Cleveland Clinic in Cleveland, Ohio. Dr. Meyer joined the Department of Anesthesia in 2003 following his Pediatric Anesthesia Fellowship at Cincinnati Children's Hospital Medical Center. Dr. Meyer is a staff anesthesiologist, as well as an attending physician in the Division of Pain Management, caring for patients with acute pain. In addition, Dr. Meyer is an attending physician for StarShine Hospice, the pediatric hospice at Cincinnati Children's. In 2006, Dr. Meyer received his board certification from the American Board of Hospice and Palliative Medicine. He has been an integral part of the development and implementation of the Pediatric Palliative and Comfort Care Team / PACT at Cincinnati Children's. Dr. Meyer is the PACT consulting physician, partnering with families in order to offer a range of comprehensive, family-centered care for children with chronic, complex or life-threatening conditions.
Education and Training
MD: University of Cincinnati College of Medicine, Cincinnati, Ohio, 1998.
Residency: Cleveland Clinic Foundation, Cleveland, Ohio, 2002.
Fellowship: Cincinnati Children's Hospital Medical Center, 2003.
Certification: Anesthesiology, 2004; Hospice and Palliative Medicine, 2006.
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David L. Moore, MD
Academic Information
Associate Professor, Division of Pediatric Anesthesia
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Education and Training
MD: University of Louisville, Louisville, KY, 1992.
Residency: Medical University of South Carolina, Charleston, SC, 1998.
Fellowship: University of Washington, Seattle, WA, 1999.
Certification: ABA, 1999.
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Jacquelyn Morillo-Delerme, MD
Director of Anesthesia, Liberty Campus
Academic Information
Associate Professor, Division of Pediatric Anesthesia
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Specialties
Pediatric cardiac anesthesiology
Education and Training
MD: Universidad Central Del Caribe, Cayey, Puerto Rico.
Residency: Boston University Hospital, 1988; Mercy Hospital, Pittsburgh, PA, 1990-1991.
Fellowship: University Health Center, Pittsburgh, PA, 1991-1992.
Certification: Anesthesiology, 1994.
Publications
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Varughese AM, Morillo-Delerme J, Kurth CD. Quality management in the delivery of pediatric anesthesia care. Int Anesthesiol Clin. 2006 Winter;44(1):119-39. Review.
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Mario Patino, MD
Anesthesiologist
Academic Information
Assistant Professor, Division of Pediatric Anesthesia
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Specialties
Clinical InterestsNeonatal anesthesia; liver transplantation; regional anesthesia Research InterestPerioperative outcomes in pediatric anesthesia
Biography
Dr. Mario Patino is an American Board Certified Anesthesiologist who completed his residency at the Cleveland Clinic. Dr. Patino joined as a faculty in 2008 after finishing his fellowship in Pediatric Anesthesia at Cincinnati Children’s Hospital Medical Center.
Education and Training
MD: Universidad del Valle, Cali, Colombia, South America, 1996.
Internship: Cleveland Clinic, Cleveland, Ohio, 2003-2004.
Residency: Cleveland Clinic, Cleveland, Ohio, 2004-2007.
Fellowship: Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, 2008.
Certification: American Board of Anesthesiology, 2008. PALS 2008. ACLS 2008.
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Joseph P. Previte, MD, FAAP
Director of Anesthesia Information and Communication Services
Academic Information
Associate Professor, Division of Pediatric Anesthesia
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Specialties
Fetal surgery anesthesia; liver transplant anesthesia; spine and neuro-surgery; medical information system management
Biography
Joseph Previte, MD, FAAP, performs all types of pediatric anesthesia, except cardiac. He is also part of the Fetal Anesthesia Care Team, Spine Surgery Care Team and Bariatric Team, and he is the Neurosurgery Champion for the Anesthesia department. Dr. Previte is interested in information technology in the health care setting and manages and directs several IT projects in the Anesthesia department. He is currently directing the implementation of Centricity, a perioperative-wide (from the preoperative evaluation through the postoperative note) computerized documentation system tailored for the anesthetic care of the pediatric patient. This system will be integrated with a perioperative-wide documentation system.
Education and Training
MD: West Virginia University School of Medicine, Morgantown, WV, 1989.
Internship: West Virginia University Medical Center, Morgantown, WV, 1990.
Residency: The Hospital of the University of Pennsylvania, Philadelphia, PA, 1993.
Fellowship: The Children's Hospital of Philadelphia, Philadelphia, PA, 1993.
Certification: Anesthesiology, 1995.
Publications
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Meyer M, Previte JP. Aspiration Pneumonitis in Children. Complications in Anesthesia, 2nd Edition. 2007 641-43. Robinson M, Previte JP. Complications of EXIT Procedure. Complications in Anesthesia, 2nd Edition. 2007 607-10. Previte JP. Information and communication system implementation in anesthesia. Int Anesthesiol Clin. 2006 Winter;44(1):179-97. Review. Wu J, Previte JP, Adler E, Myers T, Ball J, Gunter JB. Spontaneous ignition, explosion, and fire with sevoflurane and barium hydroxide lime. Anesthesiology. 2004 Aug;101(2):534-7. Cook-Sather SD, Liacouras CA, Previte JP, Markakis DA, Schreiner MS. Gastric fluid measurement by blind aspiration in paediatric patients: a gastroscopic evaluation. Can J Anaesth. 1997 Feb;44(2):168-72.
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John B. Rose, MD
has clinical research interests in pediatric pain management. Specific areas of interest include: factors which contribute to chronic pain and disability in adolescents and pharmacologic management of acute and chronic pain conditions.
513-636-7768
john.rose@cchmc.org
John B. Rose, MD
Academic Information
Professor, Division of Pediatric Anesthesia
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Education and Training
MD: University of Pennsylvania, School of Medicine, Philadelphia, PA, 1980. Residency: Pediatrics, Children’s Hospital National Medical Center, Washington, DC; Anesthesiology, Hospital of the University of Pennsylvania, Philadelphia, PA. Fellowship: Pediatric Anesthesiology & Critical Care Medicine; Children’s Hospital of Philadelphia, Philadelphia, PA. Certifications: Pediatrics, 1984; Anesthesiology, 1987.
Publications
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Guite JW, Logan DE, McCue R, Sherry DD, Rose JB. Parental beliefs and worries regarding adolescent chronic pain. Clinical Journal Pain. 2009;25:223-32. Zempsky WT, Bean-Lijewski J, Kauffman RE, Koh JL, Malviya SV, Rose JB, Richards PT, Gennevois DJ. Needle-free powder lidocaine delivery system provides rapid effective analgesia for venipuncture or cannulation pain in children: randomized, double-blind Comparison of Venipuncture and Venous Cannulation Pain After Fast-Onset Needle-Free Powder Lidocaine or Placebo Treatment trial. Pediatrics. 2008 May;121(5):979-87.
Ganesh A, Rose JB, Wells L, Ganley T, Gurnaney H, Maxwell LG, DiMaggio T, Milovcich K, Scollon M, Feldman JM, Cucchiaro G. Continuous peripheral nerve blockade for inpatient and outpatient postoperative analgesia in children. Anesth Analg. 2007 Nov;105(5):1234-42.
Guite JW, Logan DE, Sherry DD, Rose JB. Adolescent self-perception: associations with chronic musculoskeletal pain and functional disability. J Pain. 2007 May;8(5):379-86.
Harty TP, Dib-Hajj SD, Tyrrell L, Blackman R, Hisama FM, Rose JB, Waxman SG. Na(V)1.7 mutant A863P in erythromelalgia: effects of altered activation and steady-state inactivation on excitability of nociceptive dorsal root ganglion neurons. J Neurosci. 2006 Nov 29;26(48):12566-75.
Logan DE, Guite JW, Sherry DD, Rose JB. Adolescent-parent relationships in the context of adolescent chronic pain conditions. Clin J Pain. 2006 Jul-Aug;22(6):576-83.
Cucchiaro G, Adzick SN, Rose JB, Maxwell L, Watcha M. A comparison of epidural bupivacaine-fentanyl and bupivacaine-clonidine in children undergoing the Nuss procedure. Anesth Analg. 2006 Aug;103(2):322-7.
Nathan A, Rose JB, Guite JW, Hehir D, Milovcich K. Primary erythromelalgia in a child responding to intravenous lidocaine and oral mexiletine treatment. Pediatrics. 2005 Apr;115(4):e504-7.
Logan DE, Rose JB. Is postoperative pain a self-fulfilling prophecy? Expectancy effects on postoperative pain and patient-controlled analgesia use among adolescent surgical patients. J Pediatr Psychol. 2005 Mar;30(2):187-96.
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Senthilkumar Sadhasivam, MD, MPH
is a pediatric anesthesiologist who has clinical and translational research programs in personalizing analgesia and improving perioperative outcomes. His clinical research is focused on personalizing perioperative opioid analgesia in children. Clinical and translational research in fetal anesthesia is his secondary focus.
513-636-4408
senthilkumar.sadhasivam@cchmc.org
Senthilkumar Sadhasivam, MD, MPH
Academic Information
Assistant Professor, Division of Pediatric Anesthesia
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Specialties
Pediatric pain management; regional anesthesia; clinical research on improving perioperative outcomes
Education and Training
MBBS: Thanjavur Medical College, India, 1993. MD: AIIMS, New Delhi, India, 1999. Residency: Beth Israel Deaconess Medical Center, Harvard University, Boston, MA. Fellowship: Children's Hospital of Philadelphia, 2004.
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Nancy Bard Samol, MD
Academic Information
Assistant Professor, Division of Pediatric Anesthesia
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Education and Training
BS: Biology, Indiana University, Bloomington, Indiana, 1997.
MD: University of Cincinnati College of Medicine, Cincinnati, Ohio, 2002.
Internship: Internal Medicine, Good Samaritan Hospital, Cincinnati, Ohio, 2003.
Residency: Anesthesiology, University of Cincinnati, Cincinnati, Ohio, 2006.
Pediatric Anesthesiology Fellowship: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, Present.
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Ximena Soler, MD
Staff Anesthesiologist
Academic Information
Assistant Professor, Division of Pediatric Anesthesia
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Specialties
Pediatric regional anesthesia; clinical and didactic teaching; international outreach
Education and Training
MD: Pontificia Universidad Javeriana, Bogata, Colombia, 1997. Internship: Penn State Hershey Medical Center, Hershey, PA, 2001. Residency: Penn State University, M.S. Hershey Medical Center, Hershey, PA, 2003. Fellowship: Pediatric Anesthesia, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2004. Certification: Anesthesiology, 2004; ECFMG, 2004; ACLS Provider, 2007; ACLS Instructor, 2007; PALS Provider, 2007; PALS Instructor, 2008.
Publications
Kimatian SJ, Saliba KJ, Soler X, Valentine EA, Coleman ML, Kunselman, AR, Schuler, HG, Barnes ML, Thirumala PD, Myers JL. The influence of neurophysiologic monitoring on the management of pediatric cardiopulmonary bypass. ASAIO Journal 2008; 54:467-469.
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James P. Spaeth, MD
Director, Cardiac Anesthesia
is a pediatric cardiac anesthesiologist and the Director of Cardiac Anesthesia. His clinical research interests include the effect of congenital cardiac disease and cardiac surgery on neurodevelopmental outcomes, and the use of cerebral monitoring during the perioperative period. He is also involved in Quality Improvement work focused on improving the safety of pediatric anesthesia.
513-636-4408
james.spaeth@cchmc.org
James P. Spaeth, MD
Director, Cardiac Anesthesia
Staff Anesthesiologist
Academic Information
Associate Professor, Division of Pediatric Anesthesia
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Specialties
Cardiac anesthesia; neurologic injury in children with congenital heart disease; improving perioperative safety
Education and Training
MD: University of Virginia School of Medicine, Charlottesville, VA, 1993. Internship: Internal Medicine, University of Virginia Medical Center, Charlottesville, VA, 1994. Residency: Anesthesiology, University of California, San Diego Medical Center, San Diego, CA, 1997. Fellowship: Pediatric Anesthesiology, Children's Hospital of Philadelphia, Philadelphia, PA, 1998. Certification: Anesthesiology, 1998.
Publications
View PubMed Publications
Gunter JB, McAuliffe JJ, Beckman EC, Wittkugel EP, Spaeth JP, Varughese AM. A factorial study of ondansetron, metoclopramide, and dexamethasone for emesis prophylaxis after adenotonsillectomy in children. Paediatr Anaesth. 2006 Nov;16(11):1153-65. Dent CL, Spaeth JP, Jones BV, Schwartz SM, Glauser TA, Hallinan B, Pearl JM, Khoury PR, Kurth CD. Brain magnetic resonance imaging abnormalities after the Norwood procedure using regional cerebral perfusion. J Thorac Cardiovasc Surg. 2006 Jan;131(1):190-7.
Aronson LA, Spaeth JP. Frontiers in pediatric anesthesia: cardiac anesthesia. Int Anesthesiol Clin. 2006 Winter;44(1):33-49.
Dent CL, Spaeth JP, Jones BV, Schwartz SM, Glauser TA, Hallinan B, Pearl JM, Khoury PR, Kurth CD. Brain magnetic resonance imaging abnormalities after the Norwood procedure using regional cerebral perfusion. J Thorac Cardiovasc Surg. 2005 Dec;130(6):1523-30. Loepke AW, Spaeth JP. Glucose and Heart Surgery: Neonates Are Not Just Small Adults. Anesthesiology. 2004 Jun;100(6):1345-52.
Baker RC, Schubert CJ, Kirwan KA, Lenkauskas SM, Spaeth JT. After-hours telephone triage and advice in private and nonprivate pediatric populations. Arch Pediatr Adolesc Med. 1999 Mar;153(3):292-6.
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