Khurana Hershey Lab
Publications

Publications

Stevens, ML; Zhang, Z; Johansson, E; Ray, S; Jagpal, A; Ruff, BP; Kothari, A; He, H; Martin, LJ; Ji, H; et al. Disease-associated KIF3A variants alter gene methylation and expression impacting skin barrier and atopic dermatitis risk. Nature Communications. 2020; 11:4092.

Johansson, E; Myers, JM B; Martin, LJ; He, H; Ryan, P; LeMasters, GK; Bernstein, DI; Lockey, J; Hershey, GK K. Identification of two early life eczema and non-eczema phenotypes with high risk for asthma development. Clinical and Experimental Allergy. 2019; 49:829-837.

Biagini Myers, JM; Schauberger, E; He, H; Martin, LJ; Kroner, J; Hill, GM; Ryan, PH; LeMasters, GK; Bernstein, DI; Lockey, JE; et al. A Pediatric Asthma Risk Score to better predict asthma development in young children. Journal of Allergy and Clinical Immunology. 2019; 143:1803-1810.e2.

Murrison, LB; Brandt, EB; Myers, JB; Hershey, GK K. Environmental exposures and mechanisms in allergy and asthma development. The Journal of Clinical Investigation. 2019; 129:1504-1515.

Bolcas, PE; Brandt, EB; Zhang, Z; Myers, JM B; Ruff, BP; Hershey, GK K. Vitamin D supplementation attenuates asthma development following traffic-related particulate matter exposure. Journal of Allergy and Clinical Immunology. 2019; 143:386-394.e3.

Ghandikota, S; Hershey, GK K; Mersha, TB. GENEASE: real time bioinformatics tool for multi-omics and disease ontology exploration, analysis and visualization. Editor, Stegle O. Bioinformatics. 2018; 34:3160-3168.

Simmons, JM; Biagini Myers, JM; Martin, LJ; Kercsmar, CM; Schuler, CL; Pilipenko, VV; Kroner, JW; He, H; Austin, SR; Nguyen, HT; et al. Ohio Pediatric Asthma Repository: Opportunities to Revise Care Practices to Decrease Time to Physiologic Readiness for Discharge. Hospital Pediatrics. 2018; 8:305-313.

Ramirez, LP; Wendroth, H; Martin, LJ; Pilipenko, VV; He, H; Kroner, J; Ryan, PH; LeMasters, GK; Lockey, JE; Bernstein, DI; et al. High number of early respiratory infections in association with allergic sensitization to mold promotes childhood asthma. Journal of Allergy and Clinical Immunology. 2018; 141:1921-1924.e4.

Johansson, E; Hershey, GK K. Contribution of an impaired epithelial barrier to the atopic march. Annals of Allergy, Asthma, and Immunology. 2018; 120:118-119.

Gonzalez, T; Myers, JM B; Herr, AB; Hershey, GK K. Staphylococcal Biofilms in Atopic Dermatitis. Current Allergy and Asthma Reports. 2017; 17:81.

Johansson, E; Myers, JM B; Martin, LJ; He, H; Pilipenko, V; Mersha, T; Weirauch, M; Salomonis, N; Ryan, P; LeMasters, GK; et al. KIF3A genetic variation is associated with pediatric asthma in the presence of eczema independent of allergic rhinitis. Journal of Allergy and Clinical Immunology. 2017; 140:595-598.e5.

Filuta, AL; Amezcua, P; Ruff, BP; Biagini, JM; Kroner, J; He, H; Brandt, EB; Martin, LJ; Palumbo, JS; Khurana Hershey, GK; et al. The key roles of thrombin and fibrinogen in human infant and mice atopic dermatitis models. Allergy: European Journal of Allergy and Clinical Immunology. 2024; 79:239-242.

Dahal, A; Chang, WC; Almasri, C; Johansson, E; Hurd, M; Velasquez, V; Grashel, B; Spagna, D; Jenkins, S; Morgan, D; et al. Temporal relationships between Staphylococcus aureus colonization, filaggrin expression, and pediatric atopic dermatitis. Allergy: European Journal of Allergy and Clinical Immunology. 2024; 79:104-115.

Bragg, MG; Westlake, M; Alshawabkeh, AN; Bekelman, TA; Camargo, CA; Catellier, DJ; Comstock, SS; Dabelea, D; Dunlop, AL; Hedderson, MM; et al. Opportunities for Examining Child Health Impacts of Early-Life Nutrition in the ECHO Program: Maternal and Child Dietary Intake Data from Pregnancy to Adolescence. Current Developments in Nutrition. 2023; 7:102019.

Biagini, JM; Martin, LJ; He, H; Bacharier, LB; Gebretsadik, T; Hartert, TV; Jackson, DJ; Kim, H; Miller, RL; Rivera-Spoljaric, K; et al. Performance of the Pediatric Asthma Risk Score across Diverse Populations. 2023; 2.

Keet, C; Sicherer, SH; Bunyavanich, S; Visness, C; Fulkerson, PC; Togias, A; Davidson, W; Perry, S; Hamrah, S; Calatroni, A; et al. The SunBEAm birth cohort: Protocol design. 2023; 2:100124.

Bochkov, YA; Devries, M; Tetreault, K; Gangnon, R; Lee, S; Bacharier, LB; Busse, WW; Camargo, CA; Choi, T; Cohen, R; et al. Rhinoviruses A and C elicit long-lasting antibody responses with limited cross-neutralization. Journal of Medical Virology. 2023; 95:e29058.

Miller, RL; Schuh, H; Chandran, A; Aris, IM; Bendixsen, C; Blossom, J; Breton, C; Camargo, CA; Canino, G; Carroll, KN; et al. Incidence rates of childhood asthma with recurrent exacerbations in the US Environmental influences on Child Health Outcomes (ECHO) program. Journal of Allergy and Clinical Immunology. 2023; 152:84-93.

Phelan, KJ; Dill-McFarland, KA; Kothari, A; Segnitz, RM; Burkle, J; Grashel, B; Jenkins, S; Spagna, D; Martin, LJ; Haslam, DB; et al. Airway transcriptome networks identify susceptibility to frequent asthma exacerbations in children. Journal of Allergy and Clinical Immunology. 2023; 152:73-83.

Brandt, EB; Ruff, BP; Filuta, AL; Chang, WC; Shik, D; Khurana Hershey, GK. Thymic stromal lymphopoietin rather than IL-33 drives food allergy after epicutaneous sensitization to food allergen. Journal of Allergy and Clinical Immunology. 2023; 151:1660-1666.e4.

Gill, K; Moore, C; Nwogu, O; Kroner, JW; Chang, W; Stevens, ML; Kyzy, AB; Biagini, JM; Devonshire, AL; Kottyan, L; et al. B cell repertoire in children with skin barrier dysfunction supports altered IgE maturation associated with allergic food sensitization. 2023; 4:2023.02.01.526538.

Patel, S; Altman, M; Cox, M; Bacharier, L; Calatroni, A; Gill, M; Stokes, J; Liu, A; Cohen, R; Makhija, M; et al. Epithelial-Associated Inflammatory Pathways Underlie Residual Asthma Exacerbations in Urban Children Treated with Mepolizumab Therapy. Journal of Allergy and Clinical Immunology. 2023; 151:ab222.

Biagini, J; Martin, L; He, H; Bacharier, L; Gebretsadik, T; Hartert, T; Jackson, D; Kim, H; Miller, R; Rivera-Spoljaric, K; et al. The Pediatric Asthma Risk Score: A New Gold Standard for Asthma Prediction. Journal of Allergy and Clinical Immunology. 2023; 151:ab320.

Da Silva Antunes, R; Frazier, A; Pomés, A; Calatroni, A; Wood, R; O'Connor, G; Pongracic, J; Hershey, GK; Kercsmar, C; Gill, M; et al. Down-Modulation of Cockroach (CR) Allergen-specific Th2 Cell Responses Following Subcutaneous German Cockroach Allergen Immunotherapy (SCIT). Journal of Allergy and Clinical Immunology. 2023; 151:ab322.

Pennington, J; Rasnick, E; Martin, LJ; Biagini, JM; Mersha, TB; Parsons, A; Khurana Hershey, GK; Ryan, P; Brokamp, C. Racial Fairness in Precision Medicine: Pediatric Asthma Prediction Algorithms. American Journal of Health Promotion. 2023; 37:239-242.

Satish, L; Chang, W; Dahal, A; Johansson, E; makenna eversole, ; Schuetz, M; Grashel, B; daniel spagna, ; seth jenkins, ; veronica velasquez, ; et al. A New Algorithm Identifying Association of Staphylococcus aureus Strains with Low Expression of Filaggrin in Atopic Dermatitis. Journal of Allergy and Clinical Immunology. 2023; 151:ab146.

DeVore, S; Schuetz, M; Lujan, H; Ohayon, D; Kothari, A; He, H; Hahn, J; Satish, L; Herr, A; Biagini, J; et al. CARD14 is a Novel Regulator of MYC Expression and Function in Human Keratinocytes. Journal of Allergy and Clinical Immunology. 2023; 151:ab127.

Zoratti, E; Wood, R; O, G; Pongracic, J; Makhija, M; Hershey, GK; Sherenian, M; Gill, M; Gruchalla, R; Chambliss, J; et al. The Effect of Subcutaneous German Cockroach Immunotherapy (SCIT) on Nasal Allergen Challenge (NAC) and Cockroach-specific Antibody Responses Among Urban Children and Adolescents. Journal of Allergy and Clinical Immunology. 2023; 151:ab320.

Dahal, A; Chang, W; Almasri, C; Johansson, E; makenna eversole, ; Velasquez, V; spagna, d; jenkins, s; Grashel, B; Satish, L; et al. Low non-lesional filaggrin mediates longitudinal Staphylococcus aureus skin colonization, leading to worse atopic dermatitis clinical outcomes in the MPAACH cohort. Journal of Allergy and Clinical Immunology. 2023; 151:ab192.

Phelan, K; Dill-McFarland, K; Kothari, A; daniel spagna, ; seth jenkins, ; Grashel, B; Burkle, J; Martin, L; david haslam, ; Biagini, J; et al. Airway transcriptome networks identify susceptibility to frequent asthma exacerbations in children. Journal of Allergy and Clinical Immunology. 2023; 151:ab73.

Gaberino, C; Segnitz, RM; Cox, M; Bacharier, L; Calatroni, A; Gill, M; Stokes, J; Liu, A; Cohen, R; Makhija, M; et al. Mepolizumab Alters Regulation of Airway Type-2 Inflammation in Urban Children with Asthma by Disrupting Eosinophil Gene Expression but Enhancing Mast Cell and Epithelial Pathways. Journal of Allergy and Clinical Immunology. 2023; 151:ab125.

Nguyen, RH N; Knapp, EA; Li, X; Camargo, CA; Conradt, E; Cowell, W; Derefinko, KJ; Elliott, AJ; Friedman, AM; Khurana Hershey, GK; et al. Characteristics of Individuals in the United States Who Used Opioids During Pregnancy. Journal of Women's Health. 2023; 32:161-170.

Dapas, M; Thompson, EE; Wentworth-Sheilds, W; Clay, S; Visness, CM; Calatroni, A; Sordillo, JE; Gold, DR; Wood, RA; Makhija, M; et al. Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings. Editor, Pan W. PLoS Genetics. 2023; 19:e1010594.

Altman, MC; Kattan, M; O'Connor, GT; Murphy, RC; Whalen, E; LeBeau, P; Calatroni, A; Gill, MA; Gruchalla, RS; Liu, AH; et al. Associations between outdoor air pollutants and non-viral asthma exacerbations and airway inflammatory responses in children and adolescents living in urban areas in the USA: a retrospective secondary analysis. The Lancet Planetary Health. 2023; 7:e33-e44.

Nanishi, M; Chandran, A; Li, X; Stanford, JB; Alshawabkeh, AN; Aschner, JL; Dabelea, D; Dunlop, AL; Elliott, AJ; Gern, JE; et al. Association of Severe Bronchiolitis during Infancy with Childhood Asthma Development: An Analysis of the ECHO Consortium. Biomedicines. 2023; 11:23.

Hartley, K; Ryan, PH; Gillespie, GL; Perazzo, J; Wright, JM; Rice, GE; Donovan, GH; Gernes, R; Hershey, GK K; LeMasters, G; et al. Residential greenness, asthma, and lung function among children at high risk of allergic sensitization: a prospective cohort study. Environmental Health: A Global Access Science Source. 2022; 21:52.

Washington, C; Dapas, M; Biddanda, A; Magnaye, KM; Aneas, I; Helling, BA; Szczesny, B; Boorgula, MP; Taub, MA; Kenny, E; et al. African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans. Genome Medicine: medicine in the post-genomic era. 2022; 14:112.

Namjou, B; Lape, M; Malolepsza, E; DeVore, SB; Weirauch, MT; Dikilitas, O; Jarvik, GP; Kiryluk, K; Kullo, IJ; Liu, C; et al. Multiancestral polygenic risk score for pediatric asthma. Journal of Allergy and Clinical Immunology. 2022; 150:1086-1096.

DeVore, SB; Khurana Hershey, GK. The role of the CBM complex in allergic inflammation and disease. Journal of Allergy and Clinical Immunology. 2022; 150:1011-1030.

Snyder, BM; Gebretsadik, T; Turi, KN; McKennan, C; Havstad, S; Jackson, DJ; Ober, C; Lynch, S; McCauley, K; Seroogy, CM; et al. Association of citrulline concentration at birth with lower respiratory tract infection in infancy: Findings from a multi-site birth cohort study. Frontiers in Pediatrics. 2022; 10:979777.

Wissel, BD; Percy, Z; Mihalic, AP; Ellis, RV; Hershey, GK K. MD-PhD Students Are Underrepresented in the Gold Humanism Honor Society. Academic Medicine. 2022; 97:1254-1255.

Jackson, DJ; Bacharier, LB; Gergen, PJ; Gagalis, L; Calatroni, A; Wellford, S; Gill, MA; Stokes, J; Liu, AH; Gruchalla, RS; et al. Mepolizumab for urban children with exacerbation-prone eosinophilic asthma in the USA (MUPPITS-2): a randomised, double-blind, placebo-controlled, parallel-group trial. The Lancet. 2022; 400:502-511.

Seibold, MA; Moore, CM; Everman, JL; Williams, BJ M; Nolin, JD; Fairbanks-Mahnke, A; Plender, EG; Patel, BB; Arbes, SJ; Bacharier, LB; et al. Risk factors for SARS-CoV-2 infection and transmission in households with children with asthma and allergy: A prospective surveillance study. Journal of Allergy and Clinical Immunology. 2022; 150:302-311.

Filuta, A; Amezcua, PK; Chang, W; Biagini, J; Kroner, J; He, H; Grashel, B; Almasri, C; Martin, L; Palumbo, JS; et al. LB1033 Thrombin contributes to atopic dermatitis pathogenesis and staphylococcus aureus skin colonization in children. Journal of Investigative Dermatology. 2022; 142:b36.

Zanobetti, A; Ryan, PH; Coull, B; Brokamp, C; Datta, S; Blossom, J; Lothrop, N; Miller, RL; Beamer, PI; Visness, CM; et al. Childhood Asthma Incidence, Early and Persistent Wheeze, and Neighborhood Socioeconomic Factors in the ECHO/CREW Consortium. JAMA Pediatrics. 2022; 176:759-767.

Fulkerson, PC; Lussier, SJ; Bendixsen, CG; Castina, SM; Gebretsadik, T; Marlin, JS; Russell, PB; Seibold, MA; Everman, JL; Moore, CM; et al. Human Epidemiology and RespOnse to SARS-CoV-2 (HEROS): Objectives, Design and Enrollment Results of a 12-City Remote Observational Surveillance Study of Households with Children using Direct-to-Participant Methods. 2022; 3:2022.07.09.22277457.

McCauley, KE; Flynn, K; Calatroni, A; DiMassa, V; LaMere, B; Fadrosh, DW; Lynch, KV; Gill, MA; Pongracic, JA; Khurana Hershey, GK; et al. Seasonal airway microbiome and transcriptome interactions promote childhood asthma exacerbations. Journal of Allergy and Clinical Immunology. 2022; 150:204-213.

MacDonald, M; Chang, WC; Martin, LJ; Khurana Hershey, GK; Biagini, JM. The Pediatric Asthma Risk Score: More does not mean better. Annals of Allergy, Asthma, and Immunology. 2022; 128:729-730.

Stevens, ML; Mersha, TB; Zhang, Z; Kothari, A; Khurana Hershey, GK. Skin depletion of Kif3a resembles the pediatric atopic dermatitis transcriptome profile. Human Molecular Genetics. 2022; 31:1588-1598.

Guilbert, TW; Biagini, JM; Ramsey, RR; Keidel, K; Curtsinger, K; Kroner, JW; Durrani, SR; Stevens, M; Pilipenko, V; Martin, LJ; et al. Treatment by biomarker-informed endotype vs guideline care in children with difficult-to-treat asthma. Annals of Allergy, Asthma, and Immunology. 2022; 128:535-543.e6.

Biagini, JM; Kroner, JW; Baatyrbek kyzy, A; Gonzales, A; He, H; Stevens, M; Grashel, B; Spagna, D; Paul, S; Patel, R; et al. Longitudinal atopic dermatitis endotypes: An atopic march paradigm that includes Black children. Journal of Allergy and Clinical Immunology. 2022; 149:1702-1710.e4.

Vesper, S; Wymer, L; Kroner, J; Pongracic, JA; Zoratti, EM; Little, FF; Wood, RA; Kercsmar, CM; Gruchalla, RS; Gill, MA; et al. Association of mold levels in urban children's homes with difficult-to-control asthma. Journal of Allergy and Clinical Immunology. 2022; 149:1481-1485.

Johansson, E; Biagini, JM; Martin, LJ; He, H; Kroner, JW; Almasri, C; Velasquez, V; Sonzogni, M; DeVore, SB; Spagna, D; et al. Vitamin D, skin filaggrin, allergic sensitization, and race. Annals of Allergy, Asthma, and Immunology. 2022; 128:399-407.e3.

DeVore, SB; Stevens, ML; He, H; Biagini, JM; Kroner, JW; Martin, LJ; Khurana Hershey, GK. Novel role for caspase recruitment domain family member 14 and its genetic variant rs11652075 in skin filaggrin homeostasis. Journal of Allergy and Clinical Immunology. 2022; 149:708-717.

O'Hehir, RE; Holgate, ST; Sheikh, A; Hershey, GK K. Preface. Allergy Essentials. : Elsevier; Elsevier; 2022.

Murrison, LB; Ren, X; Preusse, K; He, H; Kroner, J; Chen, X; Jenkins, S; Johansson, E; Biagini, JM; Weirauch, MT; et al. TSLP disease-associated genetic variants combined with airway TSLP expression influence asthma risk. Journal of Allergy and Clinical Immunology. 2022; 149:79-88.

O’Hehir, RE; Holgate, ST; Sheikh, A; Khurana Hershey, GK. Preface.

Khurana Hershey, GK; Sherenian, MG; Mersha, TB. 2 Precision Medicine. Allergy Essentials. : Elsevier; Elsevier; 2022.

O’Hehir, RE; Holgate, ST; Khurana Hershey, GK; Sheikh, A. Allergy Essentials.

Altman, MC; Flynn, K; Rosasco, MG; Dapas, M; Kattan, M; Lovinsky-Desir, S; O'Connor, GT; Gill, MA; Gruchalla, RS; Liu, AH; et al. Inducible expression quantitative trait locus analysis of the MUC5AC gene in asthma in urban populations of children. Journal of Allergy and Clinical Immunology. 2021; 148:1505-1514.

Bekelman, TA; Dabelea, D; Ganiban, JM; Law, A; McGovern Reilly, A; Althoff, KN; Mueller, N; Camargo, CA; Duarte, CS; Dunlop, AL; et al. Regional and sociodemographic differences in average BMI among US children in the ECHO program. Obesity. 2021; 29:2089-2099.

Johnson, CC; Havstad, SL; Ownby, DR; Joseph, CL M; Sitarik, AR; Biagini Myers, J; Gebretsadik, T; Hartert, TV; Khurana Hershey, GK; Jackson, DJ; et al. Pediatric asthma incidence rates in the United States from 1980 to 2017. Journal of Allergy and Clinical Immunology. 2021; 148:1270-1280.

da Silva Antunes, R; Sutherland, A; Frazier, A; Schulten, V; Pomés, A; Glesner, J; Calatroni, A; Altman, MC; Wood, RA; O'Connor, GT; et al. Heterogeneity of magnitude, allergen immunodominance, and cytokine polarization of cockroach allergen-specific T cell responses in allergic sensitized children. Clinical and Translational Allergy. 2021; 11:e12073.

Johansson, E; Martin, LJ; He, H; Chen, X; Weirauch, MT; Kroner, JW; Khurana Hershey, GK; Biagini, JM. Second-hand smoke and NFE2L2 genotype interaction increases paediatric asthma risk and severity. Clinical and Experimental Allergy. 2021; 51:801-810.

Zhu, T; Zhang, X; Chen, X; Brown, AP; Weirauch, MT; Guilbert, TW; Khurana Hershey, GK; Biagini, JM; Ji, H. Nasal DNA methylation differentiates severe from non-severe asthma in African-American children. Allergy: European Journal of Allergy and Clinical Immunology. 2021; 76:1836-1845.

Sherenian, MG; Kothari, A; Biagini, JM; Kroner, JW; Baatyrbek kyzy, A; Johannson, E; Atluri, G; He, H; Martin, LJ; Khurana Hershey, GK. Sensitization to peanut, egg or pets is associated with skin barrier dysfunction in children with atopic dermatitis. Clinical and Experimental Allergy. 2021; 51:666-673.

Brandt, EB; Bolcas, PE; Shik, D; Ruff, BP; Hershey, GK K. TSLP rather than IL-33 signaling drives intestinal mucosal mast accumulation and allergen-induced diarrhea in mice following epicutaneous sensitization to food allergen. Journal of immunology (Baltimore, Md. : 1950). 2021; 206:94.01.

Mersha, TB; Afanador, Y; Johansson, E; Proper, SP; Bernstein, JA; Rothenberg, ME; Hershey, GK K. Resolving Clinical Phenotypes into Endotypes in Allergy: Molecular and Omics Approaches. Clinical Reviews in Allergy and Immunology. 2021; 60:200-219.

Hallmark, B; Wegienka, G; Havstad, S; Billheimer, D; Ownby, D; Mendonca, EA; Gress, L; Stern, DA; Myers, JB; Hershey, GK K; et al. Chromosome 17q12-21 Variants Are Associated with Multiple Wheezing Phenotypes in Childhood. American Journal of Respiratory and Critical Care Medicine. 2021; 203:864-870.

Choi, T; Devries, M; Bacharier, LB; Busse, W; Camargo, CA; Cohen, R; Demuri, GP; Evans, MD; Fitzpatrick, AM; Gergen, PJ; et al. Enhanced Neutralizing Antibody Responses to Rhinovirus C and Age-Dependent Patterns of Infection. American Journal of Respiratory and Critical Care Medicine. 2021; 203:822-830.

Brooks, CC; Martin, LJ; Pilipenko, V; He, H; LeMasters, GK; Lockey, JE; Bernstein, DI; Ryan, PH; Hershey, GK K; Myers, JM B. NAT1 genetic variation increases asthma risk in children with secondhand smoke exposure. Journal of Asthma (Informa). 2021; 58:284-292.

Ryan, PH; Brokamp, C; Blossom, J; Lothrop, N; Miller, RL; Beamer, PI; Visness, CM; Zanobetti, A; Andrews, H; Bacharier, LB; et al. A distributed geospatial approach to describe community characteristics for multisite studies. Journal of Clinical and Translational Science. 2021; 5:e86.

Gonzalez, T; Stevens, ML; Kyzy, AB; Alarcon, R; He, H; Kroner, JW; Spagna, D; Grashel, B; Sidler, E; Martin, LJ; et al. Biofilm propensity of Staphylococcus aureus skin isolates is associated with increased atopic dermatitis severity and barrier dysfunction in the MPAACH pediatric cohort. Allergy: European Journal of Allergy and Clinical Immunology. 2021; 76:302-313.

Stevens, ML; Gonzalez, T; Schauberger, E; Baatyrbek kyzy, A; Andersen, H; Spagna, D; Kalra, MK; Martin, LJ; Haslam, D; Herr, AB; et al. Simultaneous skin biome and keratinocyte genomic capture reveals microbiome differences by depth of sampling. Journal of Allergy and Clinical Immunology. 2020; 146:1442-1445.

Schuler, CL; Myers, JM B; Kercsmar, CM; Pilipenko, VV; Kroner, JW; Simmons, JM; Austin, SR; Gunkelman, SM; Ross, KR; McCoy, KS; et al. Weighing in on asthma: Insights on BMI, magnesium, and hospitalizations from the Ohio Pediatric Asthma Repository. Journal of Asthma (Informa). 2020; 57:1280-1287.

DeVore, SB; Gonzalez, T; Sherenian, MG; Herr, AB; Khurana Hershey, GK. On the surface: Skin microbial exposure contributes to allergic disease. Annals of Allergy, Asthma, and Immunology. 2020; 125:628-638.

Stevens, ML; Zhang, Z; Johansson, E; Ray, S; Jagpal, A; Ruff, BP; Kothari, A; He, H; Martin, LJ; Ji, H; et al. Disease-associated KIF3A variants alter gene methylation and expression impacting skin barrier and atopic dermatitis risk. Nature Communications. 2020; 11:4092.

Bolcas, PE; Brandt, EB; Ruff, BP; Kalra, M; Khurana Hershey, GK. Cysteamine prevents asthma development and reduces airway hyperresponsiveness in experimental asthma. Allergy: European Journal of Allergy and Clinical Immunology. 2020; 75:2675-2677.

Sheehan, WJ; Krouse, RZ; Calatroni, A; Gergen, PJ; Gern, JE; Gill, MA; Gruchalla, RS; Khurana Hershey, GK; Kattan, M; Kercsmar, CM; et al. Aeroallergen Sensitization, Serum IgE, and Eosinophilia as Predictors of Response to Omalizumab Therapy During the Fall Season Among Children with Persistent Asthma. Journal of Allergy and Clinical Immunology: In Practice. 2020; 8:3021-3028.e2.

Brandt, EB; Bolcas, PE; Ruff, BP; Hershey, GK K. IL33 contributes to diesel pollution-mediated increase in experimental asthma severity. Allergy: European Journal of Allergy and Clinical Immunology. 2020; 75:2254-2266.

Cox, J; Ryan, P; Burkle, J; Jandarov, R; Mendell, MJ; Hershey, GK; Lemasters, G; Reponen, T. Quantitative and semiquantitative estimates of mold exposure in infancy and childhood respiratory health. Environmental Epidemiology. 2020; 4:e101.

Myers, JM B; Sherenian, MG; Kyzy, AB; Alarcon, R; An, A; Flege, Z; Morgan, D; Gonzalez, T; Stevens, ML; He, H; et al. Events in Normal Skin Promote Early-Life Atopic Dermatitis-The MPAACH Cohort. Journal of Allergy and Clinical Immunology: In Practice. 2020; 8:2285-2293.e6.

Schauberger, E; Myers, JM B; He, H; Martin, LJ; Arshad, SH; Kurukulaaratchy, R; Hershey, GK K. Use of the Pediatric Asthma Risk Score to predict allergic and nonallergic asthma. Annals of Allergy, Asthma, and Immunology. 2020; 124:629-631.e2.

Jackson, DJ; Bacharier, LB; Calatroni, A; Gill, MA; Hu, J; Liu, AH; Wheatley, LM; Gem, JE; Gruchalla, RS; Hershey, GK K; et al. Serum IL-6: A biomarker in childhood asthma?. Journal of Allergy and Clinical Immunology. 2020; 145:1701-1704.e3.

Ober, C; McKennan, CG; Magnaye, KM; Altman, MC; Washington, C; Stanhope, C; Naughton, KA; Rosasco, MG; Bacharier, LB; Billheimer, D; et al. Expression quantitative trait locus fine mapping of the 17q12-21 asthma locus in African American children: a genetic association and gene expression study. The Lancet Respiratory Medicine. 2020; 8:482-492.

Myers, JB; Sherenian, M; Kyzy, AB; Alarcon, R; An, A; Flege, Z; Morgan, D; Gonzalez, T; Stevens, M; He, H; et al. The Mechanisms of Atopic Dermatitis to Asthma in Children (MPAACH) Cohort: Novel Atopic Dermatitis Endotypes. Journal of Allergy and Clinical Immunology. 2020; 145:ab337.

Alarcon, R; Kroner, J; Kyzy, AB; An, A; Hershey, GK; Myers, JB. Predictors of Persistent and Recurrent Wheeze in Children in The Mechanisms of Progression of Atopic Dermatitis to Asthma in Children (M-PAACH) Cohort. Journal of Allergy and Clinical Immunology. 2020; 145:ab341.

Ji, H; Zhang, X; Myers, JB; Chen, X; Weirauch, M; Guilbert, T; Hershey, GK. DNA methylation Variation Associated with the Severity of Childhood Asthma. Journal of Allergy and Clinical Immunology. 2020; 145:ab344.

Brandt, EB; Bolcas, PE; Ruff, BP; Hershey, GK K. TSLP contributes to allergic airway inflammation induced by diesel exhaust particle exposure in an experimental model of severe asthma. Clinical and Experimental Allergy. 2020; 50:121-124.

Progressive accumulation of hyperinflammatory NKG2Dlow NK cells in early childhood severe atopic dermatitis

"Atopic dermatitis (AD) manifests as skin inflammation and is often observed in children that later develop allergies and asthma." Read the Abstract

KIF3A Gene Variation Provides Key Clues for Asthma-Eczema Connection

Scientists and clinicians observed long ago that eczema often precedes the development of asthma in children. The bigger scientific question has involved uncovering the common link that connects the skin and the lungs, leading to the progression of allergy between the two.

Read the Report