Biostatistics and Epidemiology Research
Designing Statistical Analysis to Improve Child Health
The Division of Biostatistics and Epidemiology (DBE) partners with nearly all of the clinical and translational research programs of Cincinnati Children’s. Our expertise is the design and statistical analysis of studies that advance understanding of child health. That expertise helps ensure that the research done at Cincinnati Children’s is world class.
DBE is currently engaged in collaborative, independent and industry grants, totaling more than $1 million in one year in direct support to DBE. In 2010, DBE faculty and staff worked in collaboration with 35 other Cincinnati Children’s divisions and authored or coauthored more than 100 articles submitted for peer review, of which about 70 were published or accepted during the year. Articles authored by DBE faculty are published in high-impact-factor journals.
Current areas of methodological interest in DBE include:
- Clinical trial design and analysis
- Causal inference and mediation analysis
- Design and analysis of observational studies, statistical genetics and genetic epidemiology
- Bayesian modeling and inference
- Functional analysis of continuous data
- Pharmacokinetics / pharmacodynamics
- Large data array analysis
- Spatial analysis and time series analysis
- Survival analysis
- Design and evaluation of surveillance systems and disease registries
- Design and evaluation of epidemiologic studies based on electronic medical records
- Biorepositories
Areas of subject-matter interest include all pediatric subspecialties, from neonatology to adolescent health, oncology to infectious diseases, contraception to assisted reproduction, radiology and functional imaging to endocrinology. Most of our research is funded by the National Institutes of Health, National Science Foundation or other extramural sources.
