Biostatistics and Epidemiology

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    Division Head

    A photo of Maurizio Macaluso, MD, DPH.

    Maurizio Macaluso, MD, DPH Director, Biostatistics and Epidemiology

    has researched topics including epidemiologic research methods; cancer epidemiology; occupational epidemiology; health effects of sexual, reproductive and contraceptive behavior; acceptability, efficacy and safety of contraceptive technology; efficacy and safety of assisted reproductive technology; infectious disease epidemiology; surveillance systems; and immunology. 

    513-803-2827
    maurizio.macaluso@cchmc.org

    Maurizio Macaluso, MD, DPH

    Director, Biostatistics and Epidemiology

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-803-2827

    Email: maurizio.macaluso@cchmc.org

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    Specialties

    Research methods; cancer; infectious disease; occupational health; sexual and reproductive health; contraception; assisted reproductive technology; surveillance systems

    Biography

    Maurizio Macaluso, MD, DPH, has 30 years of research experience in epidemiology and has held positions at the National Tumor Institute in Milan, Italy (1980-1986), at the University of Alabama at Birmingham School of Public Health (UAB, 1986-2000), and at the Centers for Disease Control and Prevention in Atlanta, GA (2000-2010).

    His research work has covered a variety of topics including epidemiologic research methods; cancer epidemiology; occupational epidemiology; health effects of sexual, reproductive and contraceptive behavior; acceptability, efficacy and safety of contraceptive technology; efficacy and safety of assisted reproductive technology; infectious disease epidemiology; surveillance systems; and immunology.

    He has authored over 180 publications and a larger number of presentations made at national and international conferences. During his academic career at the University of Alabama at Birmingham, he taught advanced doctoral courses on the analysis of epidemiologic research studies and advised over 50 masters’ students in all areas of public health and 15 doctoral students in epidemiology, biostatistics, nutrition sciences, and medical sociology.

    Education and Training

    MD: University of Palermo, Italy, 1979.

    Fellowship: Experimental Oncology, Istituto Nazionale Tumori, Milano, Italy, 1981.

    Residency: Hygiene and Preventive Medicine, University of Palermo, Italy, 1982.

    DrPH: Epidemiology, University of Alabama at Birmingham, 1991.

    Publications

    Grants

    Center for Clinical and Translational Science and Training. Director/Co-/Director of Biostatistics Epidemiology and Research Design Core. National Center for Research Resources. April 2009 – March 2014.

    Faculty

    A photo of Mekibib Altaye.

    Mekibib Altaye, PhD

    is a biostatistician interested in the design and analysis of correlated data, including developing inference procedures for intraclass correlation, and kappa statistic for binary and polynomial outcomes. Current research interest focused in modeling issues associated with high dimensional data that arise from fMRI, MRI and microbiome studies. He also mentors junior faculty, staff and students.

    513-636-5849
    mekibib.altaye@cchmc.org

    Mekibib Altaye, PhD

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-5849

    Fax: 513-636-7509

    Email: mekibib.altaye@cchmc.org

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    Specialties

    Design and analysis of correlated data. This includes developing inference procedures for intraclass correlation, and kappa statistic for binary and polynomial outcomes. Recent research interest includes modeling issues associated with high dimensional data that arise from fMRI, MRI and microbiome studies.

    Biography

    Dr. Altaye has published more than 60 peer-reviewed articles, more than 70 abstracts/posters, invited to present his work in national meetings and co-author a book chapter. He has been a co-investigator, collaborator or biostatistician in more than 20 NIH funded projects. Dr. Altaye provides support for researchers in multiple divisions as well as for the Center for Clinical and Translational Sciences and Training (CCTST). He taught biostatistics courses for the Master of Science Clinical and Translational Research program. He has obtained travel awards to attend workshops from NSF and NIH. One of his articles received a Caffey award for best clinical science or education paper from the Pediatric Radiology Society.

    Education and Training

    PhD: The University of Western Ontario, London, Canada, 1998.

    MSc: Oklahoma State University, Stillwater, OK, 1991.

    BSc: Addis Ababa Universtiy, Addis Ababa, Ethiopia, 1983.

    Publications

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    Grants

    Pediatric Functional Neuroimaging Research Network. Biostatistician. NIH/NICHD. 09/2009-09/2014.

    Neurobehavioral Effects of Insecticide Exposure in Pregnancy and Early Childhood. Biostatistician. NIH. 09/2009-06/2012.

    Role of Human Milk in Infant Nutrition and Health. Co-Investigator. NIH/NICHD. 08/2009-06/2013.

    Longitudinal DTI Study in Children Treated for congenital Hydrocephalus. Biostatistician. NIH. 09/2009-06/2013.

    Center for Clinical and Translational Science and Training. Biostatistician NIH/NCRR. 04/2009-03/2014.

    Treatment of maternal depression in home visitation: Mother and Child impacts. Co-investigator. NIH/NIMH. 12/2009-11/2014.

    Imaging the effect of centrotemporal spikes and seizures. Biostatistician. NIH/NIND. 09/2011-06/2016.

    Multisite Study of School Based Treatment Approaches for ADHD Adolescents. Biostatistician. NIH/NIMH. 08/2009-03/2014.

    A photo of Katherine Bowers.

    Katherine A. Bowers, PhD, MPH

    is a perinatal epidemiologist interested in pre-conceptual and prenatal exposures in combination with genetic effects in relation to metabolic and neurodevelopmental consequences for the offspring. 

    513-803-9203
    katherine.bowers@cchmc.org

    Katherine A. Bowers, PhD, MPH

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-9203

    Email: katherine.bowers@cchmc.org

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    Specialties

    Perinatal and genetic epidemiology; autism spectrum disorders; prenatal exposures; pregnancy complications

    Education and Training

    PhD: Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.

    Publications

    View PubMed Publications
    A photo of Melinda S. Butsch Kovacic.

    Melinda S. Butsch Kovacic, MPH, PhD

    is an epidemiologist who has clinical, translational and community-based participatory research projects. Her research group studies the genetic/epigenetic, environmental and socioeconomic basis of chronic diseases such as cancer, asthma and obesity, with specific interest in understanding how environmental exposures modify risk in vulnerable families. Her research is highly interdisciplinary with collaborators across the academic health center and in the community.

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    513-803-0130
    melinda.butsch.kovacic@cchmc.org

    Melinda S. Butsch Kovacic, MPH, PhD

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-803-0130

    Fax: 513-636-1657

    Email: melinda.butsch.kovacic@cchmc.org

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    Specialties

    Clinical and molecular epidemiology; gene-environment interactions; biomarkers; community-based participatory research  

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    Biography

    One of Dr. Butsch Kovacic’s long-term goals is to improve the understanding of how the environment modifies chronic disease risk in genetically and/or economically vulnerable children. To this end, she is the PI of an ongoing study that is evaluating associations between environmental exposures and biomarkers of oxidative stress and whether or not these biomarkers will better predict risk of severe/uncontrolled childhood asthma compared to parental report of exposure alone (previous NIEHS R21 and CCTST KL2). As part of this study, her team is evaluating diesel exhaust particle and second hand tobacco smoke exposures, as well as obesity levels, markers of inflammation and antioxidant status, genetic and socioeconomic factors, and DNA methylation patterns. As her preliminary data revealed strong associations between her outcomes and socioeconomic factors, over the last year, she has partnered with Cincinnati’s CoreChange, a grassroots advocacy group, and Seven Hills Neighborhood Houses (SHNH; http://7hillsnh.org/), a full service social service agency and community center in the West End of Cincinnati, to expand her research into the community using a community-based participatory research (CBPR) approach. To this end, she has implemented a community-based research registry and begun needs assessments using a child-centered PhotoVoice approach and adult focus groups. A peer family health COACH (Coaching On Achieving Community Health) program will begin soon. To inform these community-based studies, she is collaborating on a project seeking to develop unique multimedia educational materials targeting low-income and low-literacy caregivers with asthmatic children.

    In addition to these studies, she is also the PI of an ongoing longitudinal epidemiological study seeking to evaluate environmental and sexual exposure to human papillomavirus (HPV) in families with children diagnosed with Fanconi anemia (current NHLBI R01). Individuals with Fanconi anemia are genetically vulnerable to squamous head and neck cancers previously shown to be positively associated with HPV. Her team is testing for oral HPV DNA, HPV serological markers as well as markers of immune response. As part of this study, Dr. Butsch Kovacic regularly interacts with a community of families associated with the Fanconi Anemia Research Fund, a strong parent led advocacy group focused on the improving the lives of children with Fanconi anemia, to design, optimize and disseminate the findings from her study.

    Education and Training

    MPH: Quantitative Methods, Harvard University School of Public Health, Boston, MA, 2003.

    PhD: Biochemistry, the Ohio State University, Columbus, OH, 2002.

    Postdoctoral Fellowship: Epidemiology/Public Health, Cancer Prevention Fellowship, Hormonal and Reproductive Epidemiology Branch, Division of of Cancer Epidemiology and Genetics, National Cancer Institute, 2002-2006.

    Publications

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    Grants

    Fanconi Anemia as a Model for Susceptibility to Human Papillomavirus Infection. Principal Investigator. NIH/NHLBI. July 2011-Jun 2016.

    Epithelial Genes in Allergic Inflammation. Co- Investigator. NIH/NIAID Asthma and Allergic Diseases Cooperative Research Center. July 2011-June 2016.

    A photo of Dr. Lili Ding.

    Lili Ding, PhD

    is a biostatistician with research interest in Bayesian modeling and inference, and its applications in various fields of biomedical research, including statistical genetics, population pharmacokinetics and pharmacodynamics, multivariate survival analysis, and multilevel latent variable modeling. Dr. Ding mentors junior faculty, fellows and students in DBE and several other divisions within the hospital.

    513-803-0931
    lili.ding@cchmc.org

    Lili Ding, PhD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-0931

    Email: lili.ding@cchmc.org

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    Specialties

    Biostatistics, Bayesian statistics, statistical genetics, population PK/PD study design and modeling

    Biography

    Dr. Ding has been actively involved in collaborative research with faculty members from Adolescent Medicine, Asthma Research, Human Genetics, and Pharmacology on the design, plan, statistical analysis and report of medical research studies. She is a statistician with a keen interest in the development and application of statistical methods in biomedical research. She has published multiple research papers on statistical genetics; design of pediatric population pharmacokinetic studies; and on cancer prevention behaviors and sexually transmitted infections in adolescents. She has participated in several NIH sponsored grants and serves as principle investigator in a CCTST method grant. Dr. Ding is review editor for the Journal of Frontiers in Genetics and reviewer for the Journal of Pediatric Research.

    Education and Training

    PhD: University of Cincinnati, OH, 2010.
    MS: University of Cincinnati, OH, 2006.
    BS: Changchun University of Science and Technology, Jilin, China, 1999

    Publications

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    A photo of Lin Fei.

    Lin Fei, PhD

    is a biostatistician who is experienced in clinical trial research, drug and cosmetics discovery and development, and consumer product research. His research interests are in multivariate methods, discrete data analysis, probability theory and Bayesian modeling, and experimental designs. Dr. Fei serves as a reviewer to Communications in Statistics – Theory and Methods and Journal of Biopharmaceutical Statistics.

    513-636-2947
    lin.fei@cchmc.org

    Lin Fei, PhD

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-2947

    Email: lin.fei@cchmc.org

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    Specialties

    Mathematical statistics; clinical trial design and analysis; statistical and probability models

    Education and Training

    BS, MS: Shanghai Jiaotong University, Shanghai, China, 1984.

    MS: The Ohio State University, Columbus, OH, 1988.

    PhD: The Ohio State University, Columbus, OH, 1992.

    Publications

    A photo of Jessica Woo.

    Jessica Graus Woo, MHSA, PhD

    is a molecular epidemiologist with particular research interest in the developmental pathways leading to pediatric obesity. She is specifically interested in how genetics and early life influences, especially early diet, may impact a child’s likelihood of developing obesity and specific metabolic complications of obesity, such as insulin resistance and dyslipidemia.

    513-636-9598
    jessica.woo@cchmc.org

    Jessica Graus Woo, MHSA, PhD

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-9598

    Fax: 513-636-7509

    Email: jessica.woo@cchmc.org

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    Specialties

    Molecular epidemiology;  pediatric obesity;  genetics and early life influences on obesity;  insulin resistance; dyslipidemia

    Education and Training

    BA: Cornell University, Ithaca, NY 1993.

    MHSA: University of Michigan, Ann Arbor, MI 1995.

    PhD: University of Cincinnati, Cincinnati, OH 2004.

    Publications

    View PubMed Publications

    Grants

    Genetic and Environmental Risk Factors in Hemorrhagic Stroke.  Principal Investigator of Subcontract. National Institute of Health. 2008 - 2013

    Charlotte M. Schmidlapp Women’s Scholars Award. 2011 – 2012.

    A photo of David Hartley.

    David M. Hartley, PhD, MPH

    investigates the factors governing the emergence and transmission of infectious diseases by applying mathematical modeling and computer simulation methods. He is also interested in data analytic and information technology approaches for understanding and improving communications in healthcare settings and improving patient safety.

    513-803-7278
    david.hartley@cchmc.org

    David M. Hartley, PhD, MPH

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-803-7278

    Email: david.hartley@cchmc.org

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    Specialties

    Research

    Infectious disease epidemiology; public health surveillance; mathematical and computer modeling

    Biography

    David M. Hartley, PhD, MPH, is associate professor of pediatrics at the James M. Anderson Center for Health Systems Excellence. His work investigates the factors governing the emergence and transmission of infectious diseases by applying mathematical modeling, computer simulation, and data analytic approaches. Additionally, he is interested in applying information technology and mathematical methods to better understand and improve patient safety and communications in healthcare settings. He obtained his PhD degree in physics from the University of Maryland Baltimore County in 1996 and his MPH degree with an emphasis in epidemiology and biostatistics from the George Washington University in 2006. Dr. Hartley has served on numerous review, advisory, and expert panels, including a White House Blue Ribbon Panel charged with addressing the threat of bioterrorism directed against livestock (2003) and the DHS-NIH Research and Policy for Infectious Disease Dynamics (RAPIDD) working group (2008-2014). He has held faculty positions at the University of Maryland School of Medicine (2003-2007) and the Georgetown University School of Medicine (2007-2014).

    Education and Training

    PhD: University of Maryland Baltimore County, Baltimore, MD, 1996.

    MPH: George Washington University, Washington, DC, 2006.

    Publications

    View PubMed Publications
    A photo of Md Monir Hossain.

    Md Monir Hossain, PhD, MSc

    is a biostatistician whose methodologic research interests include the development of statistical methods for modeling spatial-temporal disease clusters; spatial structure equation modeling; mixture models; inter-rater reliability; multi-level modeling; health services and patient outcomes; and clinical trials. Areas of application include perinatal health; access to primary health care; and childhood cancer incidences. 

    513-803-8051
    md.hossain@cchmc.org

    Md Monir Hossain, PhD, MSc

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-803-8051

    Email: md.hossain@cchmc.org

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    Biography

    Dr. Hossain’s research interests focus on developing innovative statistical methods motivated by complex biomedical and environmental applications. He has developed novel spatial and spatiotemporal models for cluster detection and also in the area of cluster detection diagnostics for small area health data. Dr. Hossain's methodologic work has been published in several top biostatistics/statistics journals such as Statistics in Medicine, Computational Statistics and Data Analysis, etc. His application research in health services and patient outcomes has received numerous public attentions. He has been successfully funded via National Cancer Institute and National Heart, Lung and Blood Institute grants for his work. Dr. Hossain has over 30 peer reviewed journal papers and has also been an ad hoc reviewer of several top statistical journals. He is an elected member of the International Statistical Institute.

    Education and Training

    PhD: Statistics, Institute of Statistical Mathematics, Japan.

    MSc: Statistics, University of Dhaka, Bangladesh. 

    Publications

    A photo of Bin Huang.

    Bin Huang, PhD Biostatistician, Division of Biostatistics and Epidemiology

    is an experienced biostatistician with research interests in mediation analysis, statistical causal inference, observational/epidemiological analyses, item response modeling, and spatially correlated data. Areas of application include: pubertal development, bio-behavior, health disparity, health related quality of life (HRQoL), patient-reported outcomes (PRO), substance use risk, STI, asthma and JIA research.

    513-636-6712
    bin.huang@cchmc.org

    Bin Huang, PhD

    Biostatistician, Division of Biostatistics and Epidemiology

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Associate Professor, Affiliated Assistant Professor, Department of Mathematical Sciences, University of Cincinnati A&S College

    Phone: 513-636-6712

    Email: bin.huang@cchmc.org

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    Specialties

    Clinical Interests

    Biostatistics; puberty; substance use/abuse; STI; GE interaction; quality of life

    Reseach Interests

    Statistics mediation analyses, causal inference, clinical effectiveness research, and statistics modeling of electronic medical records and clinical registry data

    Biography

    Dr. Huang earned a Bachelor of Science degree in civil engineering from Shanghai Jiao Tong University (1991), a Master of Science degree in mathematical statistics (1995) and a PhD in biostatistics (2001) both from the University of Cincinnati. Dr. Huang joined Cincinnati Children’s in 1999 as a biostatistician and was promoted to a research associate in 2002. She started faculty appointment in 2003 at the rank of research assistant professor of pediatrics.  In 2008 she received an affiliated assistant professor appointment with the University of Cincinnati Department of Mathematical Sciences, and in 2009 she was promoted to the rank of research associate professor of pediatrics and mathematical sciences.  Dr. Huang actively collaborates with researchers in adolescent health, juvenile rheumatoid arthritis, health disparity, health related quality of life (HRQoL), patient-reported outcomes (PRO), injury prevention and sports medicine.

    Education and Training

    BS: Shanghai Jiao Tong University, Shanghai, China, 1991.

    MS: University of Cincinnati, Cincinnati, Ohio, 1995.

    PhD: Environmental Health, University of Cincinnati, Cincinnati, OH, 2002.

    Publications

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    Grants

    Explaining Racial Disparities in Child Asthma Morbidity. Co-investigator (PI, R. Kahn). National Institutes of Health / National Institute of Child Health and Human Development. May 2010–April 2015.

    Continued Studies of Environment on Puberty: GUF2. Co-investigator (PI, F. Biro). National Institutes of Health / National Institute of Environmental Health Sciences U01. Sep 2010–April 2015.

    Epidemiologic Impact of HPV Vaccination. Co-investigator (PI, J Kahn). Jan 2013–Dec 2017.

    The Cincinnati Home Injury Prevention (CHIP) Trial. Biostatistician (PI, Phelan). National Institutes of Health / National Institute of Child Health and Human Development. Sep 2010–July 2015.

    Enhancing PROMIS in Pediatric Pain, Rheumatology and Rehabilitation Research. Co-investigator (PI, DeWitt). National Institutes of Health / National Institute of Arthritis and Musculoskeletal and Skin Diseases. Sep 2009–July 2014.       

    Inpatient Asthma Care for Children: Adding a Place-Based Community-Focused Approach. Statistics Advisor (PI, Beck). National Institutes of Health. July 2014–June 2019.

    Prospective Study of Biomechanics and Early Degeneration after ACL Reconstruction. Co-investigator (PI, Paterno/Schemit). National Institutes of Health / National Institute of Arthritis and Musculoskeletal and Skin Diseases. April 2014-March 2016.

    A photo of Richard F. Ittenbach.

    Richard F. Ittenbach, PhD

    is a biostatistician who specializes in the development, validation and analysis of scales for measurement of biomedical and biobehavioral factors. He mentors junior faculty, staff and students in DBE, cardiology, cardiac surgery, biomedical informatics, and psychology. He has contributed extensively to the training curricula of the Fellows Core Curriculum in biostatistics and data management.

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    513-803-3310
    richard.ittenbach@cchmc.org

    Richard F. Ittenbach, PhD

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-803-3310

    Fax: 513-636-1254

    Email: richard.ittenbach@cchmc.org

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    Specialties

    Scale development; statistical consulting; study design.

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    Biography

    Dr. Ittenbach has authored or co-authored more than 90 peer-reviewed publications in the behavioral and biomedical sciences. He has been funded as a co-investigator and biostatistician on a number of NIH / CDC grants. He currently serves on the editorial board of four journals and reviews for several others. Dr. Ittenbach is a certified professional statistician (PStat) through the American Statistical Association and remains active in the American Statistical Association’s Section on Statistical Consulting. Areas of current professional interest include measure and scale development, mixed methods designs, as well as empirical bioethics.

    Education and Training

    PhD: University of Alabama, 1989.

    Postdoctoral Fellowship: University of Minnesota, Minneapolis, MN 1989-1991

    MHS: Johns Hopkins University, 2001.

    MED: Auburn University, 1984.

    BS: Butler University, 1980.

    Publications

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    Grants

    Tele-health Enhancement of Adherence to Medication.  Co-Investigator (K. Hommel, PI).   National Institutes of Health.  December 2010 – Nov 2015.
    A photo of Jane Khoury.

    Jane C. Khoury, PhD

    is the senior biostatistician for the study of the epidemiology of stroke in Cincinnati, and is principal investigator for the biostatistical core of a Special Program Of Translational Research In Acute Stroke. She holds a joint appointment in the Division of Endocrinology and works with many of the faculty and fellows on study design and statistical methods in development of their research studies. Her personal research interests involve the effect of intra-uterine exposure to type 1 diabetes on childhood growth, metabolism and cardiac function.

    513-636-3690
    Jane.Khoury@cchmc.org

    Jane C. Khoury, PhD

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-3690

    Fax: 513-636-7509

    Email: Jane.Khoury@cchmc.org

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    Specialties

    Stroke, diabetes in pregnancy; research design and analysis.

    Biography

    Dr. Khoury has contributed to over 200 peer-reviewed publications in medical and epidemiological research journals. She has obtained internal funding to obtain pilot data to pursue her diabetes research described above; results were recently presented and published. Dr. Khoury collaborates with researchers in General and Community Pediatrics (environmental toxin exposure related to childhood neurodevelopment), Sports Medicine (ACL injury risk), Emergency Medicine and Endocrinology. She has been funded by over 25 NIH grants as co-investigator/biostatistician. She has served on peer-review panels for grant applications and as a journal reviewer for Stroke, Pediatrics, Journal of Pediatrics, Archives of Pediatrics and Adolescent Medicine, Public Health Reports and American Journal of Epidemiology.

    Education and Training

    PhD: University of Cincinnati College of Medicine, Department of Environmental Health, Division of Epidemiology and Biostatistics, 2006.

    MS: University of Cincinnati College of Medicine, Department of Environmental Health, Division of Epidemiology and Biostatistics, 1989.

    BSc: Bath University, Bath, England, 1973.

    Publications

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    A photo of Mi-Ok Kim.

    Mi-Ok Kim, PhD Biostatistician, Biostatistics and Epidemiology

    is a biostatistician with interest in optimizing clinical trial designs to maximize patient benefits and incorporating genomic/genetic data to better predict survival times, and quantile regression analysis of clustered data. Dr. Kim mentors junior faculty, staff and students in DBE, and the Cancer and Blood Disorders Institute. She organizes a webinar series for the Biopharmaceutical section of the American Statistical Association.

    513-636-1895
    miok.kim@cchmc.org

    Mi-Ok Kim, PhD

    Biostatistician, Biostatistics and Epidemiology

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-1895

    Fax: 513- 636-7509

    Email: miok.kim@cchmc.org

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    Specialties

    Research

    Causal inference; comparative effectiveness research; longitudinal and survival data analysis; adaptive clinical trial designs

    Education and Training

    PhD: Statistics, University of Illinois at Urbana-Champaign, 2003.

    MS: Statistics, University of Illinois at Urbana-Champaign.

    Publications

    View PubMed Publications

    Grants

    Cincinnati Center for Excellence in Molecular Hematology. Biostatistician. National Institutes of Health. Sep 2010–June 2015. P30DK090971-01 (Zheng).                             

    Lineage Determination and Tissue HomeOstasis in the aged Hematopoietic System. Biostatistician. National Institutes of Health. Aug 2011–July 2016. R01 AG040118 (Zheng).                                       

    Risk Stratification & Identification of immunogenic and microbial markers of rapid disease progression in children with Crohn’s disease. Co-Investigator. Crohn's & Colitis Foundation of America. July 2008-June 2017. R01 (Denson/Kugathasan).

    Causes and Consequences of Neutrophil Dysfunction in Pediatric Crohns Disease. Director (Biostatistics Core). National Institutes of Health. Sep 2013–July 2018. R01DK098231 (Denson).

    Neurofibroma Preclinical Therapeutics. Co-Investigator. The Children’s Tumor Foundation. July 2013–July 2016. CTF (Ratner).

    Macrophage Based Gene Therapy for Hereditary Pulmonary Alveolar Proteinosis. Co-Investigator. National Institutes of Health. April 2014–March 2018. R01 (Trapnell).                                              

    Rigor of Multi-Registry CER Studies: Towards Patient-Centered Treatment Planning. Principal Investigator. National Institutes of Health / Agency for Healthcare Research and Quality. July 2014–June 2016. K18 (Kim).

    A photo of Eileen King.

    Eileen C. King, PhD

    has 24 years of experience in the design and analysis of clinical trials for health care and pharmaceutical research studies. She enjoys collaborative research and has research interests in nonparametric regression using smoothers, comparative effectiveness research using clinical data from large multi-site registries, and statistical quality control approaches for clustered data for quality improvement initiatives in health outcomes.

    513-803-1819
    eileen.king@cchmc.org

    Eileen C. King, PhD

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-803-1819

    Fax: 513-636-1254

    Email: eileen.king@cchmc.org

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    Specialties

    Clinical trials, statistical process control, data management, nonparametric regression using linear smoothers.

    Biography

    Dr. King has provided biostatistical leadership in the design, analysis, and interpretation of results from animal and human clinical research studies supporting drug discovery, early and late stage drug development, commercialization, and market support. She provided statistical expertise and oversight for the development, review, and defense of 10 new drug application submissions in the areas of gastrointestinal, cardiac, bone diseases and female sexual health. She is currently leading the growing Data Management Center to assure appropriate data management processes for data collection, data cleaning and validation, and data finalization, documentation and archival are used which lead to high quality data that can be shared with the research community at large.

    Dr. King is active in the American Statistical Association and is currently chair of the Council of Sections Governing Board. She is an associate editor for the Journal of Statistical Education. Dr. King mentors junior faculty, staff and students in DBE and Gastroenterology and the Anderson Center. She is the primary instructor of “Statistical Principles for Clinical Research Studies” in the UC College of Pharmacy.

    Education and Training

    PhD: Texas A&M University, 1988.

    MS: University of Wyoming, 1980.

    BS: Regis College, 1976.

    Publications

    Grants

    Open Source Science: Transforming Chronic Illness Care. Statistician. National Institutes of Health. Sep 2009–Aug 2014.
    A photo of Adam Lane.

    Adam Lane, PhD

    has methodological research interests in designs for phase I/II clinical trials, survival analysis and structural equation modeling. Dr. Lane is also a dedicated collaborator with both clinical and basic science researchers in bone marrow transplantation, hematology, oncology and cancer biology.

    513-803-1828
    adam.lane@cchmc.org

    Adam Lane, PhD

    Academic Information

    Instructor, UC Department of Pediatrics

    Phone: 513-803-1828

    Email: adam.lane@cchmc.org

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    Specialties

    Research

    Clinical trials; survival analysis; structural equation modeling

    Biography

    Dr. Lane joined Cincinnati Children's in July 2013. He has published novel statistical methods in the areas of adaptive and optimal experimental designs with applications to phase I and phase II clinical trials. As a graduate student he received funding from the NIH to spend the fall semester of 2011 at the University of Cambridge in the Isaac Newton Institute for Mathematical Sciences. He has also received NSF travel awards to present his research at national and international conferences.

    Education and Training

    PhD: University of Missouri, Columbia, MO, 2013.

    Publications

    A photo of Daniel Lin.

    Ping-I (Daniel) Lin, MD, PhD

    is a genetic epidemiologist and psychiatrist. His research interests have been focused on identifying genetic variants associated with neuropsychiatric diseases. Dr. Lin has discovered variants linked to clinical heterogeneity in bipolar disorder, Alzheimer’s disease and autism. He is also interested in paradoxical association findings and selection sweeps for candidate loci for schizophrenia and autism.

    513-636-2710
    ping-i.lin@cchmc.org

    Ping-I (Daniel) Lin, MD, PhD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-2710

    Email: ping-i.lin@cchmc.org

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    Specialties

    Genetic epidemiology; pharmacogenomics; clinical psychiatry

    Biography

    Dr. Lin earned his PhD from Johns Hopkins University and MD from National Taiwan University. He has published 16 peer-review research articles and one book chapter in the field of neuropsychiatric genetics. His publications in the past 7 years have been cited by more than 350 publications. One of his research articles, entitled “No Gene Is an Island: The Flip-Flop Phenomenon,” published on American Journal of Human Genetics, alone has obtained nearly 260 citations within 5 years. He received a Travel Award (only 10 recipients were selected) from 11th International Congress of Human Genetics in 2006. In 2007, Dr. Lin was invited to the press debriefing at American Society of Human Genetics Meeting. Additionally, he received an award for his genetic research of autism by Taiwan Society of Child and Adolescent Psychiatry in 2010. His current research interests are focused on pharmacogenomics research related to neuropsychiatric diseases.

    Education and Training

    PhD: Johns Hopkins University, Baltimore, MD, 2005.

    MD: National Taiwan University, Taiwan.

    Residency: Psychiatry, National Taiwan University Hospital, Taiwan.

    Certification: Psychiatry, 2012.

    Publications

    View PubMed Publications

    Grants

    The effect of FOXP2-CNTNAP2 pathway modulated by parental age on language development. Principal Investigator. NTUH, Taiwan. Jan 2012 - Jan 2013.
    A photo of Lisa Martin, PhD.

    Lisa J. Martin, PhD

    is a statistical geneticist. Dr. Martin’s goal is to advance knowledge of disease processes by integrating statistical genetics with biology and epidemiology. Through independent and collaborative research, she expects to translate genetic findings to clinical utility by developing of innovative methods and aiding researchers in designing appropriate studies to address the questions at hand.

    513-636-1244
    lisa.martin@cchmc.org

    Lisa J. Martin, PhD

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-1244

    Fax: 513-636-7509

    Email: lisa.martin@cchmc.org

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    Specialties

    Research

    Statistical genetics; allergic conditions; pediatric heart conditions; obesity

    Biography

    As a statistical geneticist, Dr. Martin’s goal is to advance knowledge of underlying disease processes by improving our understanding of genetic variation in human populations through the integration of statistical genetics with biology and epidemiology. Since joining Cincinnati Children’s in 2002, Dr. Martin has become a leader in quantitative genetics through independent and collaborative research, leadership, and teaching/mentoring. Her independent research focuses on development of novel statistical methods and the evaluation of methods for next generation data. 

    Recently, Dr. Martin published a novel statistical method (Variant Impact On Linkage Effect Test; VIOLET), which overcomes a methodological barrier to gene discovery.   Her collaborative research focuses on allergic conditions (asthma, eosinophilic esophagitis), pediatric heart conditions, and obesity.  In addition, Dr. Martin assists researchers with an interest in incorporating genetics into their research.   At the end of 2013, Dr. Martin had published 116 peer-reviewed publications (journals include Nature Genetics, PNAS, Journal of Clinical Endocrinology and Metabolism) and 2 book chapters.

    She has a strong commitment to teaching and mentorship. Beyond teaching, she has mentored over 30 individuals. Additionally, Dr. Martin is the co-director of the Cincinnati Genomic Control Cohort, an institutional resource of 1,020 population representative children with phenotypic and genetic information.  Under Dr. Martin’s leadership, utilization of this cohort has increased. 

    In summary, Dr. Martin’s work has resulted in the development of an exciting research program as well as fruitful collaborations while balancing mentoring and service.  She expects that this research will enable the translation of genetic findings to clinical utility through the development of innovative methods and greater capacity to perform complex genetic analyses particularly given the rapid evolution of technologies.

    Education and Training

    PhD: (with Honors) University of Kansas, Lawrence KS, 1999

    Post-doctoral fellow: Southwest Foundation for Biomedical Research, San Antonio TX, 2002

    Publications

    View PubMed Publications
    A photo of Jareen Meinzen-Derr.

    Jareen K. Meinzen-Derr, PhD

    is a quantitative epidemiologist focused on improving health outcomes and clinical care for children who are deaf or hard of hearing by understanding the mechanisms behind language and functional outcomes in the subset of children with hearing loss and developmental disability. She also collaborates on clinical research regarding premature infants.
    Visit the More Than Hearing Loss web page.

    513-636-7789
    jareen.meinzen-derr@cchmc.org

    Jareen K. Meinzen-Derr, PhD

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Associate Professor, UC Department of Otolaryngology, Head & Neck Surgery, UC Department of Environmental Health

    Phone: 513-636-7789

    Fax: 513-636-7509

    Email: jareen.meinzen-derr@cchmc.org

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    Specialties

    Research

    Pediatric hearing impairment; cochlear implant research; neonatal outcomes

    Visit the More Than Hearing Loss web page.

    Biography

    Dr. Meinzen-Derr has a prolific publication background in the areas of health outcomes and clinical care for children who are deaf / hard of hearing and developmental disabilities. She is focused specifically on understanding the mechanisms behind language and functional outcomes in the subset of children with hearing loss who also have an additional developmental disability. In addition to hearing and deafness research, Dr. Meinzen-Derr collaborates on clinical research regarding premature infants. She currently teaches courses as part of the Clinical Research Training Program at the University of Cincinnati, Department of Environmental Health and supports the educational curricula for fellow research education within the Divisions of Neonatology, Developmental and Behavioral Pediatrics, and Pediatric Otolaryngology. She contributes to the biostatistics and epidemiology modules of the Pediatrics Fellowship Core curriculum and leads the experimental design lectures in neonatology and developmental and behavioral pediatrics. She has developed an online curriculum for the graduate program in biostatistics and epidemiology in the Department of Environmental Health and for the Center for Clinical and Translational Science and Training.

    Education and Training

    PhD: University of Cincinnati, Cincinnati, OH, 2006.

    MPH: Univeristy of Alabama at Birmingham, Birmingham, AL, 1997.

    Publications

    View PubMed Publications

    Grants

    Early Language and Independent Functional Expectations (LIFE) of children who are deaf or hard of hearing. Principal Investigator. March of Dimes 2014-2017.

    Impact of cognition on language in pediatric hearing loss and cognitive disabilities. Principal Investigator.  Health Resources and Service Administration/Maternal and Child Health Research. 2011-2014.

    Patterned experience for preterm infants. Co-Investigator. National Institutes of Health. 2011-2016.

    Wideband clinical diagnosis and monitoring of middle-ear and cochlear function. Co-Investigator. National Institute on Deafness and Other Communication Disorders/National Institutes of Health. 2009-2014.

    Nicholas Ollberding

    Nicholas J. Ollberding, PhD

    is a nutritional epidemiologist with research interests focused on the role of diet in the etiology and the survival of cancer, dietary assessment and analysis methodology, and the molecular epidemiology of cancer. His research incorporates the use of observational and experimental research designs, as well as innovative molecular-based technologies to examine diet-disease associations.

    513-803-4432
    nicholas.ollberding@cchmc.org

    Nicholas J. Ollberding, PhD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-4432

    Email: nicholas.ollberding@cchmc.org

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    Specialties

    Nutritional epidemiology; cancer epidemiology; dietary assessment and analysis methodology; molecular epidemiology

    Biography

    Dr. Ollberding earned his PhD in behavioral nutrition with a specialization in nutritional epidemiology from Columbia University and completed postdoctoral fellowships in cancer epidemiology and prevention at the University of Hawaii Cancer Center and the University of Chicago. To date, he has published more than 20 peer-reviewed research articles in prestigious journals including the Journal of the National Cancer Institute, Blood, and Cancer Prevention Research. In addition, his research has been presented at national conferences and he has authored a book chapter in the area of nutritional epidemiology. Dr. Ollberding was the recipient of the Zerkowski Habas Foundation and Grace McLeod Scholarships while at Columbia University and received a National Cancer Institute funded postdoctoral fellowship. 

    Dr. Ollberding’s research is motivated by the fact that while diet and obesity are major contributors to morbidity and mortality in the U.S., few Americans consume diets in accordance with recommendations for optimal health or disease prevention. Specifically, his work aims to better understand the role of diet in the etiology and progression of cancer and other chronic diseases, as well as the impact of environmental- and policy-level factors on dietary behaviors including obesity. At Cincinnati Children’s, Dr. Ollberding conducts and provides support for nutritional and cancer epidemiology studies.

    Education and Training

    PhD: Columbia University, New York, 2009.

    MPhil: Columbia University, New York, 2009.

    MS: University of Cincinnati, Cincinnati, OH, 2008.

    BS: Miami University, Oxford, OH, 2004.

    Publications

    View PubMed Publications
    A photo of Joseph Rausch.

    Joseph R. Rausch, PhD Quantitative Psychologist, Behavioral Medicine and Clinical Psychology

    is interested in improving existing methodology and developing new methods for longitudinal data analysis, especially within randomized experiments. He is also interested in elucidating the dynamic relationships between psychological, behavioral, and medical outcomes.

    513-636-4336
    joseph.rausch@cchmc.org

    Joseph R. Rausch, PhD

    Quantitative Psychologist, Behavioral Medicine and Clinical Psychology

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-4336

    Fax: 513-636-7756

    Email: joseph.rausch@cchmc.org

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    Specialties

    Longitudinal data analysis; longitudinal RCTs; design and analysis of behavioral interventions; adherence to treatment regimens

    Biography

    Joseph Rausch, PhD, trained as a quantitative psychologist at the University of Notre Dame. His research focused on the analysis of change using longitudinal and time series data analytic techniques. Dr. Rausch has been published on the appropriate analysis of randomized longitudinal clinical trials and prospective longitudinal and time series data.

    He is currently investigating novel applications of mixed-effects models for the analysis of longitudinal change on behavioral and medical outcomes.

    Education and Training

    BA: University of Cincinnati, Cincinnati, OH, 2001.

    MA: University of Notre Dame, Notre Dame, IN, 2004.

    PhD: University of Notre Dame, Notre Dame, IN, 2006.

    Publications

    View PubMed Publications

    Grants

    Promoting Treatment Adherence in Adolescent Leukemia. Co-Investigator. National Institutes of Health, National Cancer Institute. 2012 - 2014.

    Effects of Adolescent Sleep Restriction on Neural and Neurobehavioral Functioning. Statistician. National Institutes of Health, National Heart, Lung and Blood Institute.  2012 - 2014.

    Clinic and Home Family Based Behavioral Treatment for Obese Preschoolers: LAUNCH. Co-Investigator.  National Institute of Health, National Institute of Diabetes and Digestive and Kidney Diseases. 2011 - 2016.

    Nonadherence: Undermining Health Outcomes in Pediatric HSCT. Co-Investigator. National Institutes of Health, National Cancer Institute. 2012 - 2017.

    Supporting Treatment Adherence Regimens in Pediatric Epilepsy: The STAR Trial. Co-Investigator, National Institutes of Health, National Institute of Child Health and Human Development. 2013 - 2018.

    Self-management of type 1 diabetes during adolescence. Co-Investigator.  National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases. 2011 - 2018.

    A photo of Patrick Ryan.

    Patrick H. Ryan, PhD, MS

    is an environmental epidemiologist with research interests in the fields of air pollution epidemiology and exposure assessment.

    513-803-4704
    patrick.ryan@cchmc.org

    Patrick H. Ryan, PhD, MS

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Assistant Professor, Department of Environmental Health

    Phone: 513-803-4704

    Email: patrick.ryan@cchmc.org

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    Specialties

    Epidemiology; air pollution; exposure assessment

    Biography

    To date, Dr. Ryan has authored more than 30 publications and has presented his research at numerous national and international conferences. He has received research funding from the National Institute of Environmental Health Sciences, the U.S. Environmental Protection Agency, the U.S. Department of Housing and Urban Development, the Centers for Disease Control and Prevention, as well as industry and private foundations. Dr. Ryan has also been an invited speaker at numerous national conferences and universities, a guest lecturer for environmental epidemiology courses at the University of Cincinnati, and has advised masters and doctoral students in epidemiology, biostatistics, and industrial hygiene in the Department of Environmental Health at the University of Cincinnati. In 2006 Dr. Ryan received a STAR award from the American Academy of Allergy, Asthma, and Immunology and in 2010 he was selected as one of ten Science Communication Fellows by Environmental Health Sciences.

    Dr. Ryan is the principal investigator of the Cincinnati Anti-Idling Campaign Study, an academic-community partnership to examine and reduce the impact of traffic-related air pollution at schools on children with asthma.  He is also co-PI of a collaborative study to develop and field test, in a cohort of asthmatic children, a personal sensor to measure exposure to ultrafine particles.  Dr. Ryan also serves as co-investigator of the Cincinnati Childhood Allergy and Air Pollution Study (CCAAPS), a longitudinal birth cohort study of the effects of diesel exhaust particles on the development of allergies and asthma. His research with the CCAAPS study includes the development of land-use regression models for air pollution exposure assessment and the association between air pollution and neurobehavioral development.   Additional research includes studies of indoor pollutants and mold, environmental exposure to asbestos in Libby, MT, and the elemental composition of PM2.5.  

    Education and Training

    PhD: Epidemiology, University of Cincinnati, Cincinnati, OH.

    MS: Epidemiology, University of Cincinnati, OH.

    Publications

    Grants

    Impact of Traffic-Related Particles on Asthma for Students in an Urban School District. Principal Investigator. National Institute of Health (NIH) National Institute of Environmental Health Sciences (NIEHS).  Oct 2009 – Sept 2012.

    Analysis of Personal and Home Characteristics Associated with the Elemental Composition of PM2.5 in Indoor, Outdoor, and Personal Air in the RIOPA Study. Principal Investigator. Health Effects Institute (HEI).  Aug 2010 – July 2012.

    Field Validation of a Personal Sensor for Ultrafine PM in Asthmatic Children. Co-Principal Investigator. NIEHS. July 2011 – June 2013.

    Diesel, Allergens, and Gene-Environment Interactions. Co-Investigator. NIEHS. July 2007 – June 2012.

    The Libby Community Childhood Health Investigation and Exposure Follow-Up Study. Co-Investigator. Co-Investigator. NIEHS. October 2009 – Sept 2013.

    Synergistic Effect of Home Exposure to Aeroallergens and Traffic-Related Air Pollution. Department of Housing and Urban Development (HUD). Co-Investigator. Apr 2011 – March 2013.

    A photo of Sheila Salisbury.

    Shelia Salisbury, PhD

    has worked in design, analysis and interpretation of results from clinical trials and observational studies. She provides statistical support for researchers in a number of divisions and provided support to assist in the development of Children’s Hospital biostatistical consulting component of the CCTST. She is also the biostatistician for Cincinnati Children’s Hospital Medical Center’s Cancer Program Data Safety Monitoring Board (DSMB).

    (513) 636-2947
    shelia.salisbury@cchmc.org

    Shelia Salisbury, PhD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: (513) 636-2947

    Email: shelia.salisbury@cchmc.org

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    Education and Training

    PhD: University of Cincinnati, 2008.

    MS: Applied Statistics, Wright State University, 1992.

    BS: Mathematics/Statistics, Wright State University, 1990.

    Publications

    View PubMed Publications
    A photo of Heidi Sucharew.

    Heidi J. Sucharew, PhD

    is a biostatistician with research interests in structural equation modeling, latent profile analysis, and latent variable modeling.  Her recent areas of application include infant neurobehavior, stroke severity, adolescent menstrual symptoms and depression, and glucose control during pregnancy.

    513-803-1920
    Heidi.Sucharew@cchmc.org

    Heidi J. Sucharew, PhD

    Academic Information

    Instructor, UC Department of Pediatrics

    Phone: 513-803-1920

    Email: Heidi.Sucharew@cchmc.org

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    Specialties

    structural equation modeling, latent profile analysis, and latent variable modeling

    Biography

    Dr. Sucharew's areas of applied research include infant neurobehavioral outcomes, stroke severity, adolescent menstrual symptoms and depression, and glucose control during pregnancy.  Her research has been funded by the NINDS, NIH/NIEHS, and NIMH.  To date, she has authored 12 publications and has presented her research at numerous national and international conferences.  Part of Dr. Sucharew’s dissertation work on Item Response Theory and skin prick testing has been selected to be highlighted as Editor’s Choice in the March 2012 edition of Pediatric Allergy and Immunology.  Dr. Sucharew has been very active as a teacher.  She contributes to the Biostatistics and Epidemiology modules of the Pediatrics Fellowship Core curriculum.  She has also developed and is the primary instructor of "Introduction to Biostatistics" online course and has served as an invited lecturer in "Design and Management of Field Studies in Epidemiology" in the graduate program in Biostatistics and Epidemiology in the Department of Environmental Health.

    Education and Training

    BA: Statistics, The College of New Jersey, Ewing, NJ, 2000

    MS: Biostatistics, University of Washington, Seattle, WA, 2002

    PhD: Biostatistics, University of Cincinnati, Cincinnati, OH, 2009

    Publications

    Grants

    Hemorrhagic and Ischemic Stroke Among Blacks and Whites.  Biostatistician. National Institute of Health / National Institute of Neurological Disorders and Stroke. July 2009 – June 2014.

    Recanalization Therapies and Markers of Stroke Outcome. Co-Investigator.  National Institute of Neurological Disorders and Stroke.  July 2008 – April 2013.

    Medication Continuity in Children Treated for ADHD. Biostatistician.  National Institute of Mental Health. Jan 2010 – Nov 2014.

    Neurobehavioral Effects of Insecticide Exposure in Pregnancy and Early Childhood. Biostatistician. National Institute of Health / National Institute of Environmental Health Sciences. Sept 2009 – Aug 2012.

    A photo of Rhonda Szczesniak.

    Rhonda D. Szczesniak, PhD

    is currently interested in statistical and epidemiological research, including functional data analysis applications, classification methods, self-modeling regressions, instrumental variables regression, and outcomes research for children with cystic fibrosis and obstructive sleep apnea. She was recently awarded a statistical methods development grant to further her research on ambulatory blood pressure monitoring and cardiac outcomes in children with obstructive sleep apnea.

    513-803-0563
    rhonda.szczesniak@cchmc.org

    Rhonda D. Szczesniak, PhD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-0563

    Email: rhonda.szczesniak@cchmc.org

    Show All

    Specialties

    Self-modeling regressions; bayesian adaptive regression splines; time series analysis; spectral analysis

    Education and Training

    PhD: Statistics, University of Kentucky, Lexington, KY, 2007.

    MS: Statistics, University of Kentucky, Lexington, KY, 2005.

    BS: Mathematics, Radford University, Radford, VA, 2003.

    Publications

    View PubMed Publications

    Grants

    Blood pressure, cardiovascular function and sleep apnea: Developing statistical models that fit (not force) the data. Principal Investigator. Center for Clinical and Translational Science and Training. 2010 - 2011.

    Development and Validation of Serum VEGF-D as a Clinical Diagnostic Test in Lymphangioleiomyomatosis. Biostatistician. Center for Clinical and Translational Science and Training. 2010 - 2011. 

    Vascular Functions in Children with Sleep-Disordered Breathing
    . Biostatistician. National Heart, Lung and Blood Institute. 2006 -2011. # R01HL080670.

    Late Preterm Birth, Ureaplasma Species and Childhood Lung Disease. Biostatistician. National Institutes of Health. 2009 - 2013. #R01 HL097064.

    Cardiac Structure and Function in Early Familial Cardiomyopathy. Mentoring Biostatistician. National Institutes of Health. 2010 - 2015. #K25 HL102244-01.  

    A photo of Bin Zhang.

    Bin Zhang, PhD

    conducts research on statistical methods in clinical trials, survival analysis, longitudinal data analysis and optimal designs. Areas of interest: cancer, infectious diseases, asthma, cardiovascular diseases, health behavior, cohort studies, case-control studies, and clinical trials. 

    513-803-8050
    bin.zhang@cchmc.org

    Bin Zhang, PhD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-8050

    Email: bin.zhang@cchmc.org

    Show All

    Biography

    Dr. Zhang joined Cincinnati Children’s in January 2012. Dr. Zhang has served as co-investigator and lead statistician in clinical trials including both adult and pediatric patients. He served as the biostatistician for the Collaborative Antiviral Study Group (CASG), providing statistical support regarding study design, protocol development, study monitoring, quality assurance, data management, report generation and statistical analyses for CASG trials. In addition, he was the deputy director of the Statistical and Data Management Center of Mycoses Study Group (MSG), and served on the Steering Committee (Design and Analysis Committee) for the Consortium of Hospitals to Advance Research on Tobacco (CHART) trials. He has published theoretical as well as collaborative articles in peer-reviewed journals. His recent paper “Evaluation of lymph node numbers for adequate staging of Stage II and III colon cancers” published in the Journal of Hematology and Oncology, May 2011, has been accessed 2023 times in the past 8 months.  

    Education and Training

    BS: University of Science and Technology of China, Hefei, Anhui, China.

    PhD: University of Missouri, Columbia, Missouri.

    Publications

    Grants

    Mycoses Study Group. Deputy Director. Statistical and Data Management Center. Feb 2010-Dec 2013.

    Clinical Trials for Antiviral Therapies. Investigator. National Institutes of Health / National Institute of Allergy and Infectious Diseases. Aug 2003-Jan 2012.

    A photo of Nanhua Zhang.

    Nanhua Zhang, PhD

    is a faculty biostatistician with research interests in developing new methods for handling missing data, comparative effectiveness research, clinical trial design, meta-analysis, scale development, and joint modeling. His applied interests include environmental health, community-based intervention, health disparity, behavioral intervention and health psychology.

    513-803-9108
    nanhua.zhang@cchmc.org

    Nanhua Zhang, PhD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-9108

    Email: nanhua.zhang@cchmc.org

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    Specialties

    Research

    Missing data; comparative effectiveness; clinical trial design; meta-analysis; scale development; joint modeling; environmental health; community-based intervention; health disparity; behavioral intervention; health psychology

    Biography

    Dr. Zhang earned his PhD in biostatistics from the University of Michigan in Ann Arbor. Prior to joining Cincinnati Children’s Hospital Medical Center, he was a faculty member at the University of South Florida in Tampa. His statistical methodology research has covered missing data, causal inference, clinical trial design, joint modeling and meta-analysis. His applied research interests include environmental health, community-based intervention, health disparity, behavioral intervention and health psychology. His research “early childhood lead exposure on academic achievement” received media coverage on TV, radio, newspapers, magazines, and various online media such as Time.com and Yahoo.com.

    Dr. Zhang has authored 20 published papers and made numerous presentations at national and international conferences. He has served as a reviewer for 15 different journals including: Biometrika, Statistics in Medicine, Statistics Sinica, Annals of Applied Statistics, American Journal of Public Health, Annals of Epidemiology, Health Education Research. He has taught graduate and advanced doctoral courses in linear models, survival analysis and statistical computing.

    Education and Training

    BS: Shanghai University of Finance and Economics, Shanghai, China.

    MS: Bowling Green State University, Bowling Green, OH.

    PhD: University of Michigan, Ann Arbor, MI.

    Publications

    View PubMed Publications

    Grants

    Job Risk Factors on Development of Osteoarthritis. Co-Investigator. National Institutes of Health/National Institute for Occupational Safety and Health. Oct 2012-Oct 2014.