• Research Faculty

  • A photo of Peter White.

    Peter S. White, PhD Director, Division of Biomedical Informatics

    serves as the director of the Division of Biomedical Informatics at Cincinnati Children’s Hospital Medical Center and as the Rieveschl Chair of the Department of Biomedical Informatics at the University of Cincinnati (UC) College of Medicine. He oversees informatics research and resources at both institutions. He also serves as co-director of Cincinnati Children’s Center for Pediatric Genomics.


    A photo of Bruce Aronow.

    Bruce J. Aronow, PhD Co-director, Computational Medicine Center

    works toward unraveling both the role and mechanism by which the functional capabilities of the human genome shape human health and our ability to adapt to stressful challenges. The lab’s current research focus is to find or support efforts to solve problems relevant to genomic medicine by developing, both independently and collaboratively, new algorithms, tools and methodologies in translational bioinformatics.
    Visit the Aronow/Jegga Lab.


    A photo of John J. Hutton.

    John J. Hutton, MD

    focuses on federated data sharing networks to support translational research, with a concentration on neuropsychiatric disorders such as bipolar spectrum disorders.


    A photo of Anil Jegga.

    Anil Goud Jegga, DVM, MRes

    designs, develops and applies novel and robust computational approaches that will accelerate the diffusion of genomics into biomedical research and education and convert the genomics big data deluge into systematized knowledge to understand the molecular basis of disease.
    Visit the Jegga Lab.


    A photo of Michal Kouril.

    Michal Kouril, PhD Director, Research IT Services

    collaborates with several Cincinnati Children's divisions on a number of innovative technology-related projects. He also oversees the group that supports the research IT needs of the Cincinnati Children's Research Foundation.


    A photo of Jason Lu.

    Long (Jason) Lu, PhD

    uses quantitative approaches from disciplines such as computer science and applied mathematics to analyze biomedical big data with the goal of addressing fundamental questions in biology and improving human health. He is interested in deciphering the human genetic blueprint, modeling complex biological systems (such as biomolecular networks and pathways), analyzing biomedical images, and data mining on medical records.
    Visit the Lu Lab.


    A photo of Jun Ma.

    Jun Ma, PhD

    researches developmental processes at a quantitative and systems level. His team investigates fundamental mechanisms of development through a combination of quantitative experimental approaches and theoretical and simulation approaches.


    A photo of Keith Marsolo.

    Keith Marsolo, PhD

    researches methods to characterize the quality and suitability of electronic health record (EHR) data, approaches to collect and extract research data from the EHR at scale, the design and instantiation of common data models to facilitate distributed research queries, and the development of informatics architectures and standards that can support multi-center learning health systems.
    Visit the Marsolo Lab.


    A photo of Jarek Meller.

    Jarek Meller, PhD Graduate Program Director, Division of Biomedical Informatics

    researches the development and application of computational methods for learning from biological data, including applications to protein structure prediction, mapping protein interactions, functional annotation and genotype-phenotype associations. State-of-the-art modeling and annotation tools developed by his group are publicly available.
    Visit the Meller Lab.


    A photo of Yizhao Ni.

    Yizhao Ni, PhD Member, Division of Biomedical Informatics

    develops machine learning, natural language processing (NLP), and information retrieval techniques to assist clinical decision making.


    A photo of John P. Pestian.

    John P. Pestian, PhD, MBA Director, Computational Medicine Center

    advances the science of natural language processing and understanding in biomedical settings. Along with a growing list of collaborators, his lab has developed neuro-cognitive algorithms that enable computers to understand concepts and semantic relationships within clinical text. Pestian also directs the Computational Medicine Center, established in 2003 by a $28 million grant from Ohio's Third Frontier Project.
    Visit the Pestian Lab.


    A photo of Nathan Salomonis.

    Nathan Salomonis, PhD

    is a genomics and bioinformatics research scientist focusing on understanding human development and genetic networks underlying disease. His lab develops computational approaches to evaluate distinct modes of gene regulation and define molecular networks that govern mammalian progenitor cell specification and human disease pathology (e.g., Sudden Infant Death Syndrome) from genome-wide experimental datasets.


    A photo of Stephen A. Spooner

    S. Andrew Spooner, MD, MS, FAAP Chief Medical Information Officer, Biomedical Informatics

    is actively involved in patient-centered research. He is interested in clinical decision support in the pediatric electronic health record.


    A photo of Michael Wagner.

    Michael Wagner, PhD Faculty Liaison, Biomedical Informatics Core

    researches the application of machine learning techniques to bioinformatics problems such as protein structure prediction, disease classification and protein identification. He is also involved in a number of projects that implement complex software and data infrastructure.


    A photo of Judith W. Dexheimer.

    Judith W. Dexheimer, PhD

    is a biomedical informatics researcher with an interest in clinical decision support systems with a goal of improving clinical care and patient outcomes. Her research focuses on decision support in the emergency department with an interest in the effectiveness and efficacy of alerts and reminders throughout the hospital.


    A photo of Eric Hall.

    Eric S. Hall, PhD

    participates in a number of interdisciplinary teams investigating prematurity and neonatal disease. Along with coordinating data collection and exchange efforts, his work involves the application of knowledge discovery techniques to clinical data sets, as well as the development of software tools to assist in the summarization of clinical data and the modeling of clinical processes.


    A photo of Kenneth M. Kaufman.

    Kenneth M. Kaufman, PhD

    investigates the genetics of complex and rare disorders using genotyping and next-generation DNA technologies. The goal of his research is to identify the underling mechanisms and genetics that lead to complex diseases such as systemic lupus erythematosus.


    A photo of Eric Kirkendall.

    Eric S. Kirkendall, MD, MBI, FAAP Associate Chief Medical Information Officer, Information Services

    performs research in patient safety, quality improvement, and resource utilization. He is particularly interested in the design and development of novel software and applications to address complex healthcare system challenges, employing techniques such as real-time data acquisition, advanced analytics, artificial intelligence, human factors, and user-centered design.


    A photo of Kakajan Komurov.

    Kakajan Komurov, PhD Member, Cancer Biology and Neural Tumors Program

    and his lab integrate computational and experimental approaches to characterize targetable cancer vulnerabilities. Their driver projects include exploiting oncogene-induced stress pathways in cancer therapy, and the study of mechanisms, implications and therapeutic vulnerabilities imposed by the severe epigenetic defects in a subset of cancers.
    Visit the Komurov Lab.


    A photo of Alexey Porollo.

    Alexey Porollo, PhD Member, Center for Autoimmune Genomics and Etiology

    is a computational biologist with research focused on the development of new prediction and analytical methods in structural bioinformatics.
    Visit the Porollo Lab website.


    A photo of Alexander J. Towbin.

    Alexander J. Towbin, MD Radiologist, Department of Radiology and Medical Imaging

    is interested in radiology informatics; cancer imaging and abdominal imaging.


    A photo of Matthew Weirauch.

    Matthew T. Weirauch, PhD

    is a computational biologist. His lab seeks to understand the mechanisms of gene transcriptional regulation. Current projects focus on characterizing transcription factor binding specificities, and developing methods for modeling their interactions with DNA, both in vitro and in vivo. His lab applies insights from basic research on transcription factor-DNA interactions to study the mechanisms underlying complex diseases.

    Visit the Weirauch Lab.


    A photo of Yan Xu.

    Yan Xu, PhD Director of Bioinformatics Core, Neonatology & Pulmonary Biology; Perinatal Institute

    has research interests that include the identification of gene signatures, regulatory networks and biological pathways controlling lung development, maturation and diseases. She is actively involved in the development of detailed developmental lung-map via high-throughput single cell genomics to provide useful tools and resources for the lung research community.