Research Support
Financial support for Beebe's research has come through the Cincinnati Children's Hospital Research Foundation, the National Institutes of Health and the American Sleep Medicine Foundation. He also acknowledges the past and ongoing support of his colleagues and mentors, especially M. Douglas Ris, PhD, Raouf Amin, MD, and David Gozal, MD, as well as numerous students who have proven to be of immeasurable support.
Current Funding
Effects of Adolescent Sleep Restriction on Neural and Neurobehavioral Functioning
NIH Grant R01 HL092149
Funding: 9/1/09-7/31/13
Principal Investigator: D. Beebe
This study examines the proximal impact of experimental sleep restriction on healthy adolescents' neural and behavioral functioning, focusing on the fundamental neurobehavioral system of sustained attention. The study aims to determine (1) the proximal impact of sleep restriction on adolescents' neurobehavioral functioning, (2) the impact of sleep restriction on adolescents' brain functioning (via EEG and fMRI measures) while they are engaged in sustained attention tasks, and (3) the relationship between neural state and neurobehavioral performance in sleep-deprived adolescents. Role: Principal Investigator.
Clinical-Translational Research Center (Behavioral Core)
NIH Grant M01 RR 08084
Funding: 1/20/97-11/30/11
Principal Investigator: A. Strauss
The Behavioral Core of University of Cincinnati College of Medicine Clinical Translational Research Center (GCRC) promotes the ability of researchers to collect and interpret data from behavioral studies of research subjects. Role: Codirector of Behavioral Core
Improved Diagnostics & Advanced Magnetic Resonance Imaging for Pediatric NPSLE
NIH Grant P30 AR047363
Funding: 7/1/08-6/30/13
Principal Investigator: H. Brunner
The goals of the study include development and testing of an efficient screening battery for neurobehavioral deficits in children with systemic lupus erythematosus, as well as investigation of the potential role of functional and structural neuroimaging as an early screening tool. Role: Site Coinvestigator.
Randomized Controlled Study of Adenotonsillectomy for Childhood Sleep Apnea.
NIH Grant U01 HL083075
Funding: 9/1/06 – 7/31/12
Principal Investigator: S. Redline
The goal of this project is to assess whether adenotonsillectomy is associated with improvement in attention and neurocognitive executive functions and sleep-related breathing disturbances, and whether changes in indices of OSA correlate with changes in other outcomes. Role: Site Coinvestigator.
Sleep Disordered Breathing in Juvenile Idiopathic Arthritis
NIH Grant R01 NR012734
Funding: 5/1/11-2/28/15
Principal Investigator: T. Ward
A large number of children with Juvenile Idiopathic Arthritis (JIA) show signs of sleep-disordered breathing (SDB) that are associated with impaired neurobehavioral function. This study will compare: 1) indices, risk factors, and types of SDB; 2) scores on neurobehavioral tests and daytime sleepiness; and 3) associations between apnea hypopnea indices and respiratory-related arousals on neurobehavioral function and daytime sleepiness in 75 children with JIA versus 75 age, sex matched control children. Role: Consultant.
