The Center for Adherence Promotion and Self-Management at Cincinnati Children’s will address the high prevalence of problems surrounding adherence to medical treatment and the impact on clinical care and research. The center will address the need for state-of-the-art science, clinical care and training that focuses on adherence promotion. Through research, clinical care and training programs, the Center for Adherence Promotion and Self-Management will address areas of national significance and contribute to the mission of Cincinnati Children’s by facilitating intradisciplinary collaboration and quality improvement.