Peter B. Manning, MD
is largely focused on cardiac surgery in infants and methods to minimize the need for blood product transfusion related to open-heart surgery in children. Dr. Manning is a leading advocate for a multidisciplinary, team approach to the management of children with heart disorders, the approach taken by the Heart Institute.
513-636-4770
peter.manning@cchmc.org
Peter B. Manning, MD
Academic Information
Professor, Division of Pediatric Surgery
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Specialties
Correction of complex cardiac defects in the newborn period, tracheal reconstruction, and blood conservation in open-heart surgery.
Biography
Peter B. Manning, MD, is director of the Cardiothoracic Surgery Division at Cincinnati Children's Hospital Medical Center. Dr. Manning's main interests include cardiac surgery in infants and methods to minimize the need for blood product transfusion related to open-heart surgery in children. In collaboration with Michael Rutter, MD of our Otorhinolaryngology Department, Dr. Manning has performed more tracheal reconstructions in children than any center in the world. Dr. Manning is a leading advocate for a multidisciplinary, team approach to the management of children with heart disorders, the approach taken by the Heart Institute. Dr. Manning joined Cincinnati Children's in 1996 from Kansas City, where he was chief of thoracic and cardiovascular surgery at Children's Mercy Hospital. He earned a medical degree at the University of Michigan in 1982. Dr. Manning completed residencies in general surgery at the University of Michigan, pediatric surgery at Children's Mercy Hospital in Kansas City, cardiothoracic surgery at Bowman Grey School of Medicine in Winston-Salem, NC, and pediatric cardiac surgery at Children's Hospital in Boston. Dr. Manning is board-certified in general surgery, pediatric surgery, surgical critical care, congenital cardiac surgery and thoracic surgery. Editor, contributor and nationally recognized cardiothoracic surgeon Dr. Manning, with contributions from numerous experts in the field, compiled Cincinnati Children's Heart Encyclopedia, a comprehensive online medical reference.
Education and Training
BS: Bucknell University, Lewisburg, PA, 1978.
MD: University of Michigan, Ann Arbor, MI, 1982.
Residency: University of Michigan, 1982 to 1988; Children's Mercy Hospital, Kansas City, MO; 1988 to 1990; Wake Forest Medical Center, Winston-Salem, NC, 1990 to 1992.
Fellowship: Children's Hospital, Boston, MA, 1992 to 1993.
Certification: General Surgery 1989 (recertified 1997, 2007), Pediatric Surgery 1992 (recertified 2001, 2009), Thoracic Surgery 1993 (recertified 2001, 2011), Surgical Critical Care 1993 (recertified 2001), Congenital Cardiac Surgery 2010.
Publications
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Manning PB, Rutter MJ, Lisec A, Gupta R, Marino BS. One slide fits all: the versatility of slide tracheoplasty with cardiopulmonary bypass support for airway reconstruction in children.J Thorac Cardiovasc Surg. 2011 Jan;141(1):155-61. Eghtesady P, Michelfelder EC, Knilans TK, Witte DP, Manning PB, Crombleholme TM. Fetal surgical management of congenital heart block in a hydropic fetus: Lessons learned from a clinical experience.J Thorac Cardiovasc Surg. 2011 Mar;141(3):835-7. Sekar P, Border WL, Kimball TR, Hirsch R, Manning PB, Khoury PR, Beekman Iii RH. Aortic arch recoarctation after the Norwood stage I palliation: the comparative accuracy of blood pressure cuff and echocardiographic Doppler gradients in detecting significant obstruction.Congenit Heart Dis. 2009 Nov;4(6):440-7. Giuliano JS Jr, Lahni PM, Bigham MT, Manning PB, Nelson DP, Wong HR, Wheeler DS. Plasma angiopoietin-2 levels increase in children following cardiopulmonary bypass.Intensive Care Med. 2008 Oct;34(10):1851-7. Nguyen MT, Dent CL, Ross GF, Harris N, Manning PB, Mitsnefes MM, Devarajan P. Urinary aprotinin as a predictor of acute kidney injury after cardiac surgery in children receiving aprotinin therapy.Pediatr Nephrol. 2008 Aug;23(8):1317-26. Bigham MT, Brady PW, Manning PB, Jacobs BR, Kimball TR, Wong HR. Therapeutic application of intrapericardial tissue plasminogen activator in a 4-month-old child with complex fibropurulent pericarditis.Pediatr Crit Care Med. 2008 Jan;9(1):e1-4. Ashcraft TM, Jones K, Border WL, Eghtesady P, Pearl JM, Khoury PR, Manning PB. Factors affecting long-term risk of aortic arch recoarctation after the Norwood procedure. Ann Thorac Surg. 2008 Apr;85(4):1397-401; discussion 1401-2. Manning PB, Rutter MJ, Border WL. Slide tracheoplasty in infants and children: risk factors for prolonged postoperative ventilatory support.Ann Thorac Surg. 2008 Apr;85(4):1187-91; discussion 1191-2. Wheeler DS, Dent CL, Manning PB, Nelson DP. Factors prolonging length of stay in the cardiac intensive care unit following the arterial switch operation.Cardiol Young. 2008 Feb;18(1):41-50. Giuliano JS Jr, Sekar P, Dent CL, Border WL, Hirsch R, Manning PB, Wheeler DS. Unilateral pulmonary edema and acute rheumatic fever. Eur J Pediatr. 2008 Apr;167(4):465-7.
Grants
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Alistair B. M. Phillips, MD, FACC, FACS
Surgical Director, Pediatric Heart Transplantation and Mechanical Circulatory Support
is interested in reducing the impact of cardiothoracic surgery on his patients. His research interest are focused on decreasing the impact of cardiopulmonary bypass by reduction of blood exposure and determining the best timing for transfusions. Also he is evaluating ways of mitigate the inflammatory effect of bypass. As Surgical Director of Heart Transplantation he is interested in developing new ways of supporting failing hearts.
513-636-1349
alistair.phillips@cchmc.org
Alistair B. M. Phillips, MD, FACC, FACS
Surgical Director, Pediatric Heart Transplantation and Mechanical Circulatory Support
Surgical Director, Adult Congenital Heart Disease
Academic Information
Associate Professor, Division of Pediatric Surgery
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Specialties
Congenital heart disease including adult congenital heart disease and "hybrid" approaches to congenital heart disease; heart transplantation and mechanical circulatory support
Biography
Alistair B. M. Phillips, MD, FACC, FACS, is an attending surgeon at Cincinnati Children’s Hospital Medical Center. Dr. Phillips received his undergraduate degree from The Johns Hopkins University and his medical degree from The College of Physicians & Surgeons of Columbia University. After completing general and cardiothoracic surgery, as well as two years of research generally focused on cardiac physiology at New York Presbyterian – Cornell Medical Center, Dr. Phillips went onto New York Presbyterian – Columbia Medical Center were he completed fellowships in pacemakers/ defibrillators and pediatric cardiac surgery. Dr. Phillips is board-certified in both surgery and thoracic surgery. His clinical interests are in congenital heart disease, including adult congenital heart disease, heart and lung transplantation, and electrophysiology. He is also interested in developing novel approaches to treating congenital heart disease mainly through a hybrid approach. Dr. Phillips is actively involved in research with particular interests in inflammation and post-operative arrhythmias, understanding right ventricular morphology and the relationship of the cardiopulmonary systems. Dr. Phiillips has spent the last couple years developing a translational research team with emphasis on improve the quality of care for our patients and improving long-term outcomes. Dr. Phillips major achievements over the past 5 years are developing the adult congenital surgical program in Columbus, including an aortic aneurysm program. He started the ventricular assist device program at Nationwide Children’s Hospital, as well as a pediatric thoracic program. Dr. Phillips is currently the Surgical Director of Heart Transplant and Mechanical Circulatory Support, and Surgical Director of Adult Congenital Heart Disease at Cincinnati Children’s.
Education and Training
MD: College of Physicians & Surgeons of Columbia University, New York, NY, 1994 Residency: Surgical Intern, Department of Surgery, The New York Hospital, New York, NY, July 1994 - June 1995.
Publications
View PubMed Publications
Monreal G, Youtz DJ, Phillips AB, Eyman ME, Gorr MW, Velten C, Lucchesi PA, Wold LE, Gerhardt MA. Right ventricular remodeling in restrictive ventricular septal defect. J Mol Cell Cardiol. 2010 Oct;49: 699-706.
Olshove VF, Preston T, Gomez D, Phillips A, Galantowicz M. Perfusion techniques toward bloodless pediatric open heart surgery. J Extra Corpor Technol. 2010 Jun;42(2):122-7.
Holzer R, Marshall A, Kreutzer J, Hirsch R, Chisolm J, Hill S, Galantowicz M, Phillips A, Cheatham J, Bergerson L. Hybrid procedures: adverse events and procedural characteristics--results of a multi-institutional registry. Congenit Heart Dis. 2010 May-Jun;5(3):233-42.
Stoica SC, Philips AB, Egan M, Rodeman R, Chisolm J, Hill S, Cheatham JP, Galantowicz ME. The retrograde aortic arch in the hybrid approach to hypoplastic left heart syndrome. Ann Thorac Surg. 2009 Dec;88(6):1939-46; discussion 1946-7.
Holzer RJ, Sisk M, Chisolm JL, Hill SL, Olshove V, Phillips A, Cheatham JP, Galantowicz M. Completion angiography after cardiac surgery for congenital heart disease: complementing the intraoperative imaging modalities. Pediatr Cardiol. 2009 Nov;30(8):1075-82.
Phillips AB, Green J, Bergdall V, Yu J, Monreal G, Gerhardt M, Cheatham JP, Galantowicz M, Holzer RJ. Teaching the "hybrid approach": a novel swine model of muscular ventricular septal defect. Pediatr Cardiol. 2009 Feb;30(2):114-8.
Holzer RJ, Green J, Bergdall V, Chisolm JL, Hill SL, Galantowicz M, Cheatham JP, Phillips A. An animal model for hybrid stage I palliation of hypoplastic left heart syndrome. Pediatr Cardiol. 2009 Oct;30(7):922-7.
Monreal G, Nicholson LM, Han B, Joshi MS, Phillips AB, Wold LE, Bauer JA, Gerhardt MA. Cytoskeletal remodeling of desmin is a more accurate measure of cardiac dysfunction than fibrosis or myocyte hypertrophy. Life Sci. 2008 Dec 5;83(23-24):786-94.
Galantowicz M, Cheatham JP, Phillips A, Cua CL, Hoffman TM, Hill SL, Rodeman R. Hybrid approach for hypoplastic left heart syndrome: intermediate results after the learning curve. Ann Thorac Surg. 2008 Jun;85(6):2063-70.
Phillips AB, Ko W. Effects of ischemic preconditioning and adenosine pretreatment on myocardial function and energetics in a clinically relevant model. Life Sci. 2007 Oct 13;81(17-18):1355-61.
Grants
Development and study of novel epicardial pacing lead. Principal Investigator. Medtronic. Dec 2010 - Aug 2011.
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