Cancer and Blood Diseases Institute

  • Cancer & Blood Diseases Institute

    The vision of the Cancer and Blood Diseases Institute is to be the global leader in leading-edge cancer / blood disease care, research and education.

    Our mission is:

    • To expand innovative basic science with integrated new approaches in leading-edge translational clinical research 
    • To define new standards and models for outstanding clinical care and continual outcomes improvement
    • To provide excellence and new paradigms in education and training
    • To build a shared culture of discovery, innovation, compassion and quality

    Collaboration, Innovation and Leadership in Research

    Researchers are pursuing new clues about the causes of blood diseases, cancer and immune deficiency disorders and developing more effective targeted therapies for them through scientific discovery, innovation and multidisciplinary collaboration.

    Cincinnati Children’s has been a leader in basic science and clinical research for decades. In 2009, we established the Cancer and Blood Diseases Institute to formally align our strong clinical care and research programs, enhancing collaborations and speeding the transfer of new knowledge from the laboratory to patient care. Beyond the institute, our faculty members partner with researchers and clinicians in other research and clinical divisions, including developmental biology, immunobiology, radiology and nephrology.

    Basic Research

    Scientific inquiry drives the creation of knowledge. Researchers in the Division of Experimental Hematology and Cancer Biology explore how abnormalities in our genetic code and cell signaling pathways contribute to the development of cancer and blood diseases. These researchers seek to understand the mechanisms of blood diseases and cancer and lay the foundation for exciting new approaches to diagnosing, treating and even curing some of the most serious diseases of childhood and adolescence.

    Translational and Clinical Research

    The institute promotes close collaborations between basic scientists and the physicians who care for our patients and lead our clinical research efforts. What we learn in the laboratory will have a significant impact on future patient care, and insights from the clinic can prompt new investigations in the laboratory. Our faculty are leaders in national consortia developing new therapies for cancer, blood diseases and immune disorders. Our patients have early access to many new therapies, sometimes years before they are available at other centers.

    What Sets Our Research Program Apart

    • Well-established clinical researchers, who provide leadership for national studies
    • Leading-edge laboratory research that focuses on stem cell biology, molecular and gene therapy, leukemia biology, cell signaling, cancer biology and pathology and the use of genetically reprogrammed viruses to kill tumors
    • State-of-the-art technology, including special programs to support gene and cellular therapy initiatives
    • The ability to transfer laboratory breakthroughs to the patient care setting
    • Patient access to novel therapies, sometimes years before they are widely available
    • A commitment to educate and train researchers of the future, through fellowships, seminars and other opportunities
    • Contributions to the world-wide research community through extensive publication of research findings
  • cancer-callout2-200-clinical-image

    Our Clinical Services

    Cincinnati Children’s is a special place where hematology, oncology, bone marrow transplantation, immune deficiency and vascular malformation specialists provide sophisticated treatments.

    Learn more about our clinical services.
 
  • CBDI directors

    Left to Right: J Palumbo, J Perentesis, Y Zheng, S Davies

    CBDI directors
  • Division Data Summary

    Research and Training Details
    Faculty41
    Joint Appointment Faculty10
    Research Fellows9
    Research Students1
    Support Personnel217
    Peer Reviewed Publications144
    Clinical Activities and Training
    Clinical Staff19
    Clinical Fellows17
    Other Students7
    Inpatient Encounters23,569
    Outpatient Encounters15,475
  • Our Divisions

    faculty member works in lab.

    Read more about the talented investigators working within the four divisions of the Cancer and Blood Diseases Institute:

    - Experimental Hematology and Cancer Biology
    - Oncology
    - Hematology
    - Bone Marrow Transplantation and Immune Deficiency

  • No. 3 in Cancer Care

    US News Cancer
    Our cancer program was rated No. 3 in the country in the 2014-15 list of Best Children’s Hospitals published by U.S. News & World Report.
    AWARDS AND RANKINGS