Clinical Translational Research Center
High-Quality, Patient-Oriented Research
The Clinical Translational Research Center (CTRC) at Cincinnati Children’s provides resources that enable investigators to perform high-quality, patient-oriented research at various venues across the Academic Health Center (AHC) and the community.
We are one of 60 Clinical and Translational Science Awards consortium members throughout the United States funded by the National Institutes of Health to conduct clinical research. Our services build off the work of the General Clinical Research Center (GCRC), which has provided care to more than 25,000 infants, children, adolescents and adults since 1963.
The Clinical Translational Research Center provides all of the modern resources of clinical investigation, including biochemical assays, electron microscopy, molecular biology and genetics and mass spectrometry. We support the growth of clinical translational research and Good Clinical Practice (GCP) research skills of investigators and can give them access to additional resources through the Center for Clinical and Translational Science and Training (CCTST).
Multidisciplinary groups of pediatric, surgical, obstetrical and internal medicine subspecialists have drawn on these resources to conduct research studies in a diverse range of interest areas:
- Bone mineral accretion in infants, children and adults
- Diabetes mellitus in children and adults
- Chronic cholestatic liver disease and its complications
- Growth in chronic disease
- Growth in specific disorders, such as growth hormone resistance
- Obesity and body composition changes with age
- Gaucher disease
- Isoflavones
- Cystic fibrosis
- Behavioral science studies
Utilization Statistics
Our research center is available 24 hours a day, seven days a week. Outpatient services are in Location E, second floor. Inpatient services are in Location A, seventh floor, central.
During the grant year ending March 31, 2011, 70 principal investigators with 117 active protocols used CTRC resources as part of their studies. The research projects led to 40 article publications in reputable peer-reviewed journals, such as the Journal of Pediatrics and the Journal of the American Medical Association.
Grant-sponsored research participants made 3,394 outpatient visits to the research center and were hospitalized here for 43 inpatient days. Industry-sponsored research participants made 1,000 outpatient visits and were hospitalized for 13 inpatient days in the same time period.
Although the primary mission of the center is to provide an environment conducive to performance of patient-oriented research, nonresearch patients also used the inpatient and outpatient facilities. These patients comprised 13,010 outpatient visits and were hospitalized for 2,255 inpatient days.
