Clinical Translational Research Center

  • Facilities

    The CTRC offers investigators a number of facilities and laboratories to use for their investigations:

    Main Campus CTRC

    The main campus CTRC is dedicated to supporting pediatric and adult research unit. It is comprised of a 6 room outpatient clinic in Location E, second floor. The CTRC has inpatient admitting capabilities on A7 central for research only and mixed clinical and research admissions (including 24 hour short stays). A7 Central also includes the sleep research lab which includes 4 beds for sleep research.

    Researchers can also make use of “scatter beds” for research throughout Cincinnati Children’s, UC Medical Center,  and other community locations. CTRC Research Nurses can perform study specific skills and procedures while the subjects are admitted or being seen clinically .

    Veterans Affairs Medical Center (VAMC) Satellite Facility

    The VA Medical Center CTRC satellite facility is a unit for adult subjects with two inpatient rooms able to support cardiac monitoring, five outpatient rooms and three procedure rooms. The facility has an onsite processing lab with sample storage, as well as a local clinical lab. Staff are Certified Clinical Research Coordinators and IATA certified. It is  on the fourth floor of the Cincinnati VA Medical Center, three blocks from the Cincinnati Children’s main campus. The outpatient facility operates 6:30 am-4:30 pm (later if needed) Monday through Friday. This facility also offers inpatient and sleep study facilities by arrangement.

    Core Laboratories

    The CTRC Core Laboratories provide diverse facilities for investigators:

    The 1,000-square-foot Biochemistry Core Laboratory, in Location R, has a staff of four experienced technicians. It houses analytical equipment including 3 automated analyzers (1 general chemistry and 2 immunoassay) sufficient to perform a wide array of assays such as general clinical chemistry, HPLC, RIA, ELISA and IRMA.

    The Sample Processing Laboratory,  on the CTRC outpatient unit, houses a refrigerated centrifuge, a room temperature centrifuge, and short-term storage at temperatures of 4ºC, -20ºC and -80ºC. The lab also offers a YSI glucose analyzer for rapid bedside testing. Processing is available 24 hours a day by arrangement. with the CCHMC main hospital laboratory providing off-hours processing. This service must be set up at study start up.

    Metabolic Kitchen and Kitchenette

    The Bionutrition Core maintains research equipment and a small kitchenette adjacent to the CTRC clinic in addition to the CTRC metabolic kitchen. The metabolic kitchen at the Cincinnati Children’s Oak Campus is available for careful preparation of food for ongoing feeding studies while the kitchenette at the Main Campus CTRC supports limited preparation and measurement of study specific foods and small meals for outpatient visits. . The core also owns and operates an indirect calorimeter (Vmax Encore; Sensor Medics) for measurement of resting energy expenditure.

    DXA Facilities

    The Body Composition Core is in the CTRC unit and provides instrumentation for imaging techniques. We have two dual beam X-ray densitometers  (DXA; Hologic Inc) and a peripheral quantitative computerized tomography densitometer (pQCT) system.  We also perform other techniques for body composition assessment, including bioelectrical impedance analysis (BIA), skinfold thicknesses, and circumference measurements.