Notch Wisdom
Contents:
| Contributors | xi |
| Prologue | xv |
| 1. Notch: The Past, the Present, and the Future Spyros Artavanis-Tsakonas and Marc A. T. Muskavitch |
1 |
| 2. Mechanistic Insights into Notch Receptor Signaling from Structural and Biochemical Studies Rhett A. Kovall and Stephen C. Blacklow |
31 |
| 3. Canonical and Non-Canonical Notch Ligands Brendan D’Souza, Laurence Meloty-Kapella, and Gerry Weinmaster |
73 |
| 4. Roles of Glycosylation in Notch Signaling Pamela Stanley and Tetsuya Okajima |
131 |
| 5. Endocytosis and Intracellular Trafficking of Notch and Its Ligands Shinya Yamamoto, Wu-Lin Charng, and Hugo J. Bellen |
165 |
| 6. g-Secretase and the Intramembrane Proteolysis of Notch Ellen Jorissen and Bart De Strooper |
201 |
| 7. Two Opposing Roles of RBP-J in Notch Signaling Kenji Tanigaki and Tasuku Honjo |
231 |
| 8. Notch targets and Their Regulation Sarah Bray and Fred Bernard |
253 |
| 9. Notch Signaling in the Vasculature Thomas Gridley |
277 |
| 10. Ultradian Oscillations in Notch Signaling Regulate Dynamic Biological Events Ryoichiro Kageyama, Yasutaka Niwa, Hiromi Shimojo, Taeko Kobayashi, and Toshiyuki Ohtsuka |
311 |
| 11. Notch Signaling in Cardiac Development and Disease Donal MacGrogan, Meritxell Nus, and Jose´ Luis de la Pompa |
333 |
| 12. Notch Signaling in the Regulation of Stem Cell Self-Renewal and Differentiation Jianing Liu, Chihiro Sato, Massimiliano Cerletti, and Amy Wagers |
367 |
| 13. Notch Signaling in Solid Tumors Ute Koch and Freddy Radtke |
411 |
| 14. Biodiversity and Noncanonical Notch Signaling Pascal Heitzler |
457 |
