(All fields required)
Please enter a valid email.
Please enter your name.
Focal segmental glomerulosclerosis (FSGS) is a heterogeneous and devastating disease that is one of the major causes of renal failure. The long-term goals of this research are to provide a deeper understanding of this disease, to identify novel therapeutic targets that might lead to more effective treatments and to define gene-expression signature-based subtypes that are useful guides for therapy.
Toward these ends, we are carrying out the following specific aims:
Public Health Relevance
For most FSGS patients, there is no effective therapy, and kidney failure is the end result. We propose to use a combination of cutting-edge technologies to study the normal glomerulus as well as the diseased glomerulus, in both humans and well-defined mouse models, to better understand this disease and to help discover improved methods of treatment.
click to enlarge
3333 Burnet Avenue, Cincinnati, Ohio 45229-3026 | 1-513-636-4200 | 1-800-344-2462 | TTY: 1-513-636-4900
New to Cincinnati Children’s or live outside of the Tristate area? 1-877-881-8479
© 1999-2015 Cincinnati Children's Hospital Medical Center