• Research Faculty

  • A photo of Larry Dolan.

    Lawrence M. Dolan, MD Director, Division of Endocrinology

    investigates the natural history of obesity, insulin resistance, and diabetes mellitus with a focus on their effect on the development and progression of cardiovascular disease in youth.

    513-636-4744

    A photo of Phillipe Backeljauw.

    Philippe F. Backeljauw, MD Fellowship Program Director, Division of Endocrinology

    Within the Division of Endocrinology, Dr. Backeljauw's research emphasis relates to children with growth disorders and Turner syndrome. Ongoing studies focus on IGF-I therapy in GH resistance syndromes, as well as assessment and treatment of Turner syndrome co-morbidities. His research efforts have resulted in more than 100 publications, including peer-reviewed original manuscripts, abstracts and textbook chapters.

    513-636-8444

    A photo of Nancy Crimmins.

    Nancy A. Crimmins, MD

    is interested in genetic and environmental factors of early-onset obesity as well as timing of co-morbidities in toddlers and preschoolers with extreme obesity. She is also interested in the predictors of fatty liver disease in patients with obesity and type 2 diabetes. Dr. Crimmins is the local PI of TrialNet, a natural history study which focuses on the development of type 1 diabetes.

    513-636-4744

    A photo of Andrew Dauber.

    Andrew Dauber, MD, MMSc Program Director and Director of Translational Research, Cincinnati Center for Growth Disorders

    investigates the genetic etiology of growth disorders and other pediatric endocrine conditions. His research employs the latest in genomic technologies to discover novel genetic causes of growth disorders in patients with previously undiagnosed conditions. Further laboratory investigations are then performed to understand the underlying perturbations to growth biology.
    Visit the Dauber - Hwa Lab

    513-636-4744

    A photo of Deborah A. Elder.

    Deborah A. Elder, MD

    Dr. Elder’s current research focus is beta-cell function and glucose tolerance in different diabetes types. Specifically, she follows glucose tolerance in the cystic fibrosis population and abnormalities found in those with chronic pancreatitis. Dr. Elder is also a key member of the Pancreatic Center and Lung Transplantation Center at Cincinnati Children's. These new divisions will have mechanisms to track patient clinical data and clinical outcomes.

    513-636-4744

    A photo of Iris Gutmark-Little.

    Iris Gutmark-Little, MD

    currently conducts research in an interdisciplinary project along with engineering, radiology, cardiology, and pulmonology. The first involves a study of the TS airway, imaged using MRI, then virtually reconstructed, and analyzed to measure air flow features. The overall aim is to assess the cause of airway disease and specific treatments for this poorly described problem in the TS patient group. Similarly, a second project is ongoing and involves modeling aortic blood flow properties from TS patients who have undergone MRI for clinical purposes. The overall aim of this project is to elucidate the cause and progression of aortic disease in TS women.

    513-636-4744

    A photo of Stuart Handwerger.

    Stuart Handwerger, MD

    focuses on the transcriptional regulation of human placental development.  He examines the molecular mechanisms involved in the induction of the transcription factor AP-2alpha during the differentiation of villous cytotrophoblast cells from normal and pathologic placentas. His recent lab studies indicate that AP-alpha is a critical component of the transcription network controlling normal placental development.
    Visit the Handwerger Lab.

    513-636-4209

    A photo of Jonathan Howell.

    Jonathan C. Howell, MD, PhD

    is a clinical endocrinologist who is interested in the study of endocrine defects among patients with hematological disorders and cancer. He studies inherent endocrine deficiencies in patients with congenital anemias and the late endocrine effects of chemotherapy, radiation, chronic transfusions, and chronic steroid therapy with the aim of improving outcomes of patients who have anemia disorders or who are cancer survivors. 

    513-636-4744

    Vivian Hwa, PhD

    Vivian Hwa, PhD Basic Research Director, Cincinnati Center for Growth Disorders

    investigates the functional and cellular impacts of genetic defects identified in children with severe growth failure, who often present with a variety of co-morbidities, including immune deficiencies, insulin insensitivities, intellectual impairment, microcephaly.  These pathophysiological mutations provide unique opportunities to delineate molecular mechanism(s) of actions and improve understanding of clinical phenotypes.
    Visit the Dauber - Hwa Lab

    513-803-7337

    A photo of Jonathan Katz.

    Jonathan D. Katz, PhD

    is working to understand the role that autoreactive T lymphocytes play in the Immunopathogenesis of type 1 diabetes, the most common pediatric autoimmune disease. Major focuses include defining: (a) the control of autoreactive T cells via central and peripheral tolerance; (b) the role NKT cells play in regulating autoreactive T cells; and (c) the role dendritic cells play in activating and regulating autoreactive T cells in type 1 diabetes.

    513-636-5306

    A photo of Jane Khoury.

    Jane C. Khoury, PhD

    is the senior biostatistician for the study of the epidemiology of stroke in Cincinnati, and is principal investigator for the biostatistical core of a Special Program Of Translational Research In Acute Stroke. She holds a joint appointment in the Division of Endocrinology and works with many of the faculty and fellows on study design and statistical methods in development of their research studies. Her personal research interests involve the effect of intra-uterine exposure to type 1 diabetes on childhood growth, metabolism and cardiac function.

    513-636-3690

    A photo of Sarah Lawson.

    Sarah Lawson, MD

    focuses on the progression of heart disease in the Turner syndrome population, assessing the endocrine needs in children who have received cranial radiation for oncology treatments, and genetics associated with septo-optic dysplasia.

    513-636-4744

    A photo of Takahisa Nakamura.

    Takahisa Nakamura, PhD

    Research goal is to address questions concerning why and how inflammatory responses are initiated, coordinated, and thus involved in the development of obesity-induced metabolic diseases.

    513-636-4744

    A photo of Susan Rose.

    Susan R. Rose, MD

    investigates hypothalamic pituitary function and disorders of growth, puberty or thyroid hormone. She has special interest in the effects of neural injury on hypothalamic-pituitary function, such as after traumatic brain injury, cranial radiation, anoxia, iron overload.

    513-636-4744

    A photo of Meilan Rutter, MD.

    Meilan M. Rutter, MD, FRACP

    is a member of several multidisciplinary clinical teams, including the Neuromuscular Comprehensive Care Center and the Center for Disorders of Sex Development (DSD). Related research interests involve endocrine issues in Duchenne muscular dystrophy, currently focusing on a trial of insulin-like growth factor-I (IGF-I) therapy in this population, and participation in a multicenter trial of parental attitudes from having a child with a DSD.

    513-636-4744

    A photo of Amy Shah.

    Amy S. Shah, MD, MS

    is a pediatric endocrinologist whose research focuses on the mechanisms that contribute to early onset cardiovascular and cerebrovascular disease in adolescents with obesity and type 2 diabetes. Dr. Shah’s laboratory work focuses on the contribution of high density lipoproteins (HDL) to protect against atherosclerosis and her clinical research utilizes uses noninvasive imaging modalities to measure the atherosclerotic burden in youth. She also sees patients in clinic with diabetes, endocrine concerns and lipid abnormalities.

    513-636-4744

    A photo of Peggy Stenger.

    Peggy Joyce Stenger, DO

    focuses on disorders of bone and calcium metabolism. She is a certified clinical densitometrist and conducts a specialty clinic for the evaluation and treatment of children with metabolic bone disease, including patients with hypophosphatemic rickets. She seeks to improve bone health by identifying and the etiology and factors contributing to multiple fractures in children.

    513-636-4744

    A photo of James Wells, PhD.

    James M. Wells, PhD Director, Basic Research, Division of Endocrinology

    researches the molecular mechanisms of endoderm organogenesis in mouse and humans. The goal of this work is to identify the molecular basis of congenital defects affecting the pancreas, liver, and biliary system and to direct the differentiation of pluripotent stem cells (PSCs) into therapeutic cells for replacement therapies, such as transplantable pancreatic beta cells for patients with type-1 diabetes.
    Visit the Wells Lab.

    513-636-8767

    A photo of Nana-Hawa Yayah Jones.

    Nana-Hawa Yayah Jones, MD

    focuses on adherence in the management of type 1 diabetes and addressing barriers to care in children with chronic disease.

    513-636-4744