Endocrinology

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    Division Head

    A photo of Larry Dolan.

    Lawrence M. Dolan, MD Director, Division of Endocrinology

    investigates the natural history of obesity, insulin resistance, and diabetes mellitus with a focus on their effect on the development and progression of cardiovascular disease in youth.

    513-636-4744

    Lawrence M. Dolan, MD

    Director, Division of Endocrinology

    Director, Endocrinology Clinical Laboratory

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-4744

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    Specialties

    Clinical

    Pediatric endocrinology; diabetes mellitus

    Research

    Epidemiology of obesity; insulin resistance; abnormal carbohydrate metabolism; diabetes and their relationships to the development and progression of cardiovascular disease

    Biography

    Lawrence M. Dolan, MD, is board-certified in pediatrics and pediatric endocrinology. He has been on the faculty of Cincinnati Children's Hospital Medical Center in the Department of Pediatrics for the University of Cincinnati College of Medicine since 1983.

    Dr. Dolan is a professor of pediatrics in the Division of Endocrinology. His research focuses on the epidemiology and genetics of obesity, insulin resistance, abnormal carbohydrate metabolism, diabetes and their relationships to the development and progression of cardiovascular disease.

    Dr. Dolan received his bachelor of science degree from the University of San Francisco. He received his doctor of medicine degree from the University of California at Los Angeles.

    Dr. Dolan completed his pediatric internship and residency at the University of Minnesota. He also served as chief resident. He obtained fellowship training in pediatric endocrinology at the University of Virginia.

    Education and Training

    BS: University of San Francisco, San Francisco, CA, 1971.

    MD: University of California at Los Angeles, Los Angeles, CA, 1976.

    Residency: University of Minnesota, Minneapolis, MN, 1976 to 1979. Chief Resident, 1979.

    Fellowship: University of Virginia, Charlottesville, VA.

    Certification: Pediatrics, 1982; Pediatric Endocrinology, 1983.

    Publications

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    Grants

    SEARCH for Diabetes in Youth. Principal Investigator.  Center for Disease Control and the National Institutes of Health. Sep 2010–Oct 2015. 3 (1U18DP002709).

    Accelerated cardiovascular aging in Youth. Co-investigator. National Institutes of Health. Jan 2011–Dec 2015. R01-105591.

    Adolescent Bariatric Surgery: Assessing Benefits and Risks. Co-investigator. National Institutes of Health. Apr 2012–Mar 2017. UO1DK072493.

    Self-management of type 1 diabetes during adolescence. Co-investigator. National Institutes of Health. Jul 2013–Jun 2018. R01DK069486-06.

    SEARCH for Air. Co-investigator. National Institutes of Health. Sep 2011–Jun 2015. RO1ES019168.

    Faculty

    A photo of Phillipe Backeljauw.

    Philippe F. Backeljauw, MD Fellowship Program Director, Division of Endocrinology

    Within the Division of Endocrinology, Dr. Backeljauw's research emphasis relates to children with growth disorders and Turner syndrome. Ongoing studies focus on IGF-I therapy in GH resistance syndromes, as well as assessment and treatment of Turner syndrome co-morbidities. His research efforts have resulted in more than 100 publications, including peer-reviewed original manuscripts, abstracts and textbook chapters.

    513-636-8444
    philippe.backeljauw@cchmc.org

    Philippe F. Backeljauw, MD

    Fellowship Program Director, Division of Endocrinology

    Clinical Director, Cincinnati Growth Center

    Director, Turner Syndrome Center of Cincinnati

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-8444

    Fax: 513-636-7486

    Email: philippe.backeljauw@cchmc.org

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    Specialties

    Clinical

    Pediatric endocrinology; growth disorders; Turner syndrome

    Research

    Growth disorders; Turner syndrome 

    Biography

    In the recent years Dr. Backeljauw's research has focused on clinical trials evaluating the efficacy and safety of recombinant human IGF-I in patients with growth hormone insensitivity syndrome. These studies have led to the USFDA approval of IGF-I as a treatment for growth failure associated with primary IGF-I deficiency. The studies ended in 2012, and results have been published. He has also been involved in other multi-center studies of IGF-I therapy or combined growth hormone plus IGF-I therapy for idiopathic short stature. In collaboration with Dr. Meilan Rutter, they recently finished a comprehensive study looking at the efficacy and safety of IGF-I therapy in patients with Duchenne muscular dystrophy.

    A more recent area of research for Dr. Backeljauw, during the last five years, is related to activities in the Turner Syndrome Center. We now have conducted several clinical research projects evaluating the cardiovascular pathology, hypertension, attention deficit disorder status, gonadectomy surgery outcomes, and, in particular, vasculopathy prevalence in our large cohort of patients with Turner syndrome.

    Education and Training

    MD: University of Ghent, Belgium.

    Residency: Pediatric and Adolescent Medicine, Cleveland Clinic Foundation Children's Hospital, Cleveland, OH.

    Fellowship: Pediatric Endocrinology, University of North Carolina, Chapel Hill, NC.

    Certification: Pediatrics, 1992; recertified, 1999, 2007; Pediatric Endocrinology, 1995; recertified, 2003, 2013.

    Publications

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    A photo of Nancy Crimmins.

    Nancy A. Crimmins, MD

    is interested in genetic and environmental factors of early-onset obesity as well as timing of co-morbidities in toddlers and preschoolers with extreme obesity. She is also interested in the predictors of fatty liver disease in patients with obesity and type 2 diabetes. Dr. Crimmins is the local PI of TrialNet, a natural history study which focuses on the development of type 1 diabetes.

    513-636-4744
    nancy.crimmins@cchmc.org

    Nancy A. Crimmins, MD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4744

    Fax: 513-636-7486

    Email: nancy.crimmins@cchmc.org

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    Specialties

    Clinical Interests

    Diabetes; obesity

    Research Interests

    Obesity: etiology and treatment; maturity onset diabetes of the young; epidemiology of glucose intolerance and diabetes

    Education and Training

    MD: Indiana University School of Medicine, 2000.

    Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, 2003.

    Fellowship: Pediatric Endocrinology, Cincinnati Children's Hospital Medical Center, 2006.

    Publications

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    A photo of Andrew Dauber.

    Andrew Dauber, MD, MMSc Program Director and Director of Translational Research, Cincinnati Center for Growth Disorders

    investigates the genetic etiology of growth disorders and other pediatric endocrine conditions. His research employs the latest in genomic technologies to discover novel genetic causes of growth disorders in patients with previously undiagnosed conditions. Further laboratory investigations are then performed to understand the underlying perturbations to growth biology.

    513-636-4744
    andrew.dauber@cchmc.org

    Andrew Dauber, MD, MMSc

    Program Director and Director of Translational Research, Cincinnati Center for Growth Disorders

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4744

    Email: andrew.dauber@cchmc.org

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    Specialties

    Clinical

    Pediatric endocrinology; growth disorders; precocious puberty

    Research

    Growth disorders; precocious puberty

    Education and Training

    MD: Harvard Medical School, Boston, MA, 2000.

    MS: Clinical Investigation, Harvard Medical School, Boston, MA 2008.

    Residency: Pediatrics, Boston Combined Residency Program in Pediatrics, Boston Children's Hospital and Boston Medical Center, Boston, MA.

    Chief Resident: Pediatrics, Boston Children's Hospital, Boston, MA, 2004-2005.

    Fellowship: Pediatric Endocrinology, Boston Children's Hospital, Boston, MA.

    Certification: Pediatrics, Pediatric Endocrinology

    Publications

    View PubMed Publications
    A photo of Deborah A. Elder.

    Deborah A. Elder, MD

    Dr. Elder’s current research focus is beta-cell function and glucose tolerance in different diabetes types. Specifically, she follows glucose tolerance in the cystic fibrosis population and abnormalities found in those with chronic pancreatitis. Dr. Elder is also a key member of the Pancreatic Center and Lung Transplantation Center at Cincinnati Children's. These new divisions will have mechanisms to track patient clinical data and clinical outcomes.

    513-636-4744
    deborah.elder@cchmc.org

    Deborah A. Elder, MD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4744

    Fax: 513-803-1174

    Email: deborah.elder@cchmc.org

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    Specialties

    Clinical Interests

    Type 1 diabetes; type 2 diabetes; cystic-fibrosis-related diabetes; assessment of beta-cell function in the evaluation of total pancreatectomy and islet autotransplantation (TPAIT) in children with chronic pancreatitis; growth disorders; precocious puberty; pancreatic center member; cystic fibrosis and endocrine combined clinic; lung transplantation center member.

    Research Interests 

    Beta-cell function and glucose tolerance in a variety of different diabetes conditions.

    Education and Training

    BS: Michigan State University, 1991.

    MD: University of Kentucky College of Medicine, Lexington, KY, 1995.

    Residency: Indiana University Riley Hospital For Children, Indianapolis, IN, 1998.

    Fellowship: University of North Carolina at Chapel Hill, Chapel Hill, NC, 2001.

    Certification: Pediatric endocrinology.

    Publications

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    A photo of Iris Gutmark-Little.

    Iris Gutmark-Little, MD

    currently conducts research in an interdisciplinary project along with engineering, radiology, cardiology, and pulmonology. The first involves a study of the TS airway, imaged using MRI, then virtually reconstructed, and analyzed to measure air flow features. The overall aim is to assess the cause of airway disease and specific treatments for this poorly described problem in the TS patient group. Similarly, a second project is ongoing and involves modeling aortic blood flow properties from TS patients who have undergone MRI for clinical purposes. The overall aim of this project is to elucidate the cause and progression of aortic disease in TS women.

    513-636-4744
    iris.little@cchmc.org

    Iris Gutmark-Little, MD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4744

    Email: iris.little@cchmc.org

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    Specialties

    Clinical

    Turner syndrome; general pediatric endocrinology; growth; puberty; hypopituitarism

    Research

    Cardiovascular disease in Turner syndrome

    Biography

    Iris Gutmark-Little, MD, is board-certified in pediatrics and board-eligible in pediatric endocrinology. She has been on the faculty of Cincinnati Children's Hospital Medical Center in the Department of Pediatrics for the University of Cincinnati College of Medicine since 2010.

    Dr. Gutmark-Little is an assistant professor of pediatrics in the Division of Endocrinology. Her research focuses on the airway and great vessel anatomy and diseases in the Turner syndrome population.

    Dr. Gutmark-Little received her bachelor's of science in microbiology and chemistry from Louisiana State University. She received her doctor of medicine degree from the Johns Hopkins University School of Medicine.

    Dr. Gutmark-Little completed her pediatric internship and residency at Cincinnati Children’s Hospital Medical Center. She obtained fellowship training in Pediatric Endocrinology at Cincinnati Children’s Hospital Medical Center.

    Education and Training

    BS: Louisiana State University, Baton Rouge, Louisiana 2000.

    MD: Johns Hopkins University School of Medicine, Baltimore, Maryland 2004.

    Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 2007.

    Fellowship: Pediatric Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 2010.

    Certification: General Pediatrics, American Board of Pediatrics, 2008; Pediatric Endocrinology, American Board of Pediatrics, pending 2011.

    Publications

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    Grants

    Computational modeling in the Turner syndrome aorta. Principal Investigator. Chain of Love Foundation. Jun 2014-Jun 2015.
    A photo of Stuart Handwerger.

    Stuart Handwerger, MD

    focuses on the transcriptional regulation of human placental development.  He examines the molecular mechanisms involved in the induction of the transcription factor AP-2alpha during the differentiation of villous cytotrophoblast cells from normal and pathologic placentas. His recent lab studies indicate that AP-alpha is a critical component of the transcription network controlling normal placental development.
    Visit the Handwerger Lab.

    513-636-4209
    stuart.handwerger@cchmc.org

    Stuart Handwerger, MD

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-4209

    Fax: 513-636-7486

    Email: stuart.handwerger@cchmc.org

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    Specialties

    Regulation of gene expression in human placenta and uterine decidua during differentiation.

    Visit the Handwerger Lab.

    Education and Training

    MD: University of Maryland School of Medicine, Baltimore, MD, 1964.

    Residency: Mt. Sinai Hospital, New York, NY, 1965 to 1966.

    Fellowship: Harvard Medical School, Children's Hospital Medical Center, Boston, MA, 1968 to 1969.

    Certification: Diplomate, American Board of Pediatrics, 1969; Subspecialty Boards, Pediatric Endocrinology, 1978.

    Publications

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    A photo of Jonathan Howell.

    Jonathan C. Howell, MD, PhD

    is a clinical endocrinologist who is interested in the study of endocrine defects among patients with hematological disorders and cancer. He studies inherent endocrine deficiencies in patients with congenital anemias and the late endocrine effects of chemotherapy, radiation, chronic transfusions, and chronic steroid therapy with the aim of improving outcomes of patients who have anemia disorders or who are cancer survivors. 

    513-636-4744
    jonathan.howell@cchmc.org

    Jonathan C. Howell, MD, PhD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4744

    Email: jonathan.howell@cchmc.org

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    Specialties

    Type 1 and type 2 diabetes mellitus; endocrinopathy in bone marrow failure syndromes; growth disorders; thyroid disorders

    Biography

    Jonathan C. Howell, MD, PhD, is board certified in both pediatrics and pediatric endocrinology. He has been on the faculty of Cincinnati Children’s Hospital Medical Center in the Department of Pediatrics for the University of Cincinnati College of Medicine since 2012.

    Dr. Howell is an assistant professor of pediatrics in the Division of Endocrinology. His main clinical focus is diabetes as well as providing care for patients with endocrine disorders, including growth, thyroid, pituitary, pubertal, and adrenal dysfunction. Dr. Howell’s research focuses on the effects of congenital anemias and cancer on the endocrine system and the outcomes of chemotherapy, radiation, transfusions, and chronic steroid therapy on endocrine hormone function. 

    Dr. Howell received his Bachelor of Arts degree from Hanover College. He received his PhD from Indiana University and his MD from Indiana University School of Medicine.

    Dr. Howell completed his pediatric internship and residency at Cincinnati Children’s Hospital Medical Center, where he also served as chief resident. He also obtained his fellowship training from Cincinnati Children’s.

    Education and Training

    BA:Hanover College, Hanover, IN, 1997.

    PhD: Indiana University (Edward F. Srour, thesis adviser), Indianapolis, IN, 2003.

    MD: Indiana University School of Medicine, Indianapolis, IN, 2005.

    Residency: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2005-2008.

    Chief Residency: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2008-2009.

    Endocrinology Fellowship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2009-2012

    Certification: Pediatrics, 2008; Pediatric Endocrinology, 2013.

    Publications

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    Vivian Hwa, PhD Basic Research Director, Cincinnati Center for Growth Disorders

    investigates the functional and cellular impacts of genetic defects identified in children with severe growth failure, who often present with a variety of co-morbidities, including immune deficiencies, insulin insensitivities, intellectual impairment, microcephaly.  These pathophysiological mutations provide unique opportunities to delineate molecular mechanism(s) of actions and improve understanding of clinical phenotypes. 

    513-803-7337
    vivian.hwa@cchmc.org

    Vivian Hwa, PhD

    Basic Research Director, Cincinnati Center for Growth Disorders

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-803-7337

    Email: vivian.hwa@cchmc.org

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    Specialties

    Clinical

    Molecular basis of growth disorders; defects along the GH-IGF-I Axis; STAT5B deficiency; IGF1R resistance

    Education and Training

    BS: University of Sydney, Sydney, Australia.

    PhD: University of Illinois, Champaign-Urbana, IL.

    Publications

    View PubMed Publications
    A photo of Jonathan Katz.

    Jonathan D. Katz, PhD

    is working to understand the role that autoreactive T lymphocytes play in the Immunopathogenesis of type 1 diabetes, the most common pediatric autoimmune disease. Major focuses include defining: (a) the control of autoreactive T cells via central and peripheral tolerance; (b) the role NKT cells play in regulating autoreactive T cells; and (c) the role dendritic cells play in activating and regulating autoreactive T cells in type 1 diabetes.

    513-636-5306
    jonathan.katz@cchmc.org

    Jonathan D. Katz, PhD

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-5306

    Fax: 513-636-5355

    Email: jonathan.katz@cchmc.org

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    Specialties

    Clinical Interests

    T cells; MHC, beta cell death; islet antigens

    Research Interests

    Immunology, autoimmunity, type 1 diabetes

    Biography

    Jonathan D. Katz, PhD, focuses on autoimmune diabetes research. Autoimmune diabetes, also known as type 1 diabetes (T1D), is the most common pediatric autoimmune disease. Roughly 1/250 individuals develop T1D in the United States.There is currently no cure for T1D and the only treatment is daily exogenous insulin replacement therapy. Many T1D patients eventually develop secondary complications, such as hearth disease, blindness, peripheral neuropathy and renal failure.

    Dr. Katz's work focuses on the role that autoreactive T lymphocytes play in the disease process. His lab interested in (1) the control of autoreactive T cells via central and peripheral tolerance, (2) the role NKT cells play in regulating autoreactive T cells, and (3) the role dendritic cells play in activating and regulating autoreactive T cells in T1D.

    Most of his work uses the non-obese diabetic (NOD) mouse strain that spontaneously develops T1D with remarkable similar to the T1D seen in human patients. The availability of the NOD strain has allowed us to take a modern, reductionist molecular and cellular immunology approach to understanding the mechanism(s) and genetics underlying T1D susceptibility and disease progression. His lab makes extensive use of knockout, transgenic, regulated gene expression, targeted ablation, cell transfer and genomic studies the progression and regulation of T1D in the NOD mouse.

    Education and Training

    BS: University of California, Los Angeles, Calif., 1984.

    PhD: University of California, Los Angeles, Calif., 1990.

    Post-Doctoral Fellow: Université Louis Pasteur, Strasbourg, France, 1990-1995.

    Publications

    View PubMed Publications
    A photo of Jane Khoury.

    Jane C. Khoury, PhD

    is the senior biostatistician for the study of the epidemiology of stroke in Cincinnati, and is principal investigator for the biostatistical core of a Special Program Of Translational Research In Acute Stroke. She holds a joint appointment in the Division of Endocrinology and works with many of the faculty and fellows on study design and statistical methods in development of their research studies. Her personal research interests involve the effect of intra-uterine exposure to type 1 diabetes on childhood growth, metabolism and cardiac function.

    513-636-3690
    Jane.Khoury@cchmc.org

    Jane C. Khoury, PhD

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-3690

    Fax: 513-636-7509

    Email: Jane.Khoury@cchmc.org

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    Specialties

    Stroke, diabetes in pregnancy; research design and analysis.

    Biography

    Dr. Khoury has contributed to over 250 peer-reviewed publications in medical and epidemiological research journals. She obtained internal funding to obtain pilot data to pursue her diabetes research described above; results were presented and published. She continues to pursue outside funding to further this research. Dr. Khoury holds a joint appointment in the Division of Endocrinology, collaborating with numerous faculty and fellows on studies involving diabetes, Duchene muscular dystrophy, and Turner’s syndrome among others. She is also involved in research with General and Community Pediatrics (environmental toxin exposure related to childhood neurodevelopment), Sports Medicine (ACL injury risk) and Emergency Medicine. She has been funded by over 25 NIH grants as co-investigator and biostatistician. She has served on peer-review panels for grant applications and as a journal reviewer for Stroke, Pediatrics, Journal of Pediatrics, Archives of Pediatrics and Adolescent Medicine, Public Health Reports and American Journal of Epidemiology.

    Education and Training

    PhD: University of Cincinnati College of Medicine, Department of Environmental Health, Division of Epidemiology and Biostatistics, 2006.

    MS: University of Cincinnati College of Medicine, Department of Environmental Health, Division of Epidemiology and Biostatistics, 1989.

    BSc: Bath University, Bath, England, 1973.

    Publications

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    Grants

    Hemorrhagic and Ischemic Stroke Among Blacks and Whites. Co-Investigator. R01 NINDS/NIH. Jan 2009-Dec 2014.

    Recanalization Therapies and Markers of Stroke Outcome. Co-Investigator. P50 NINDS. Sep 2002-April 2015.

    Neurobehavioral and Neuroimaging Effects of Traffic Exposure in Children. Co-Investigator. R01 NIH. July 2012-March 2017.

    SEARCH for Diabetes in Youth, Phase 3: Registry Study. Biostatistician. Center for Disease Control & Prevention. Sep 2010-Sep 2015.

    Improving post-discharge outcomes by facilitating family-centered transitions from hospital to home. Co-Investigator. PCORI. July 2014-June 2017.

    Determine the Optimal Method for Handling Non-Detectable Values for Exposure Measurement in Epidemiologic Evaluation. PrincipaI Investigator. Center for Clinical and Translational Science Training. May 2014-April 2015.

    A photo of Sarah Lawson.

    Sarah Lawson, MD

    The progression of heart disease in the Turner Syndrome population, assessing the endocrine needs in children who have received cranial radiation for oncology treatments, and genetics associated with septo-optic dysplasia.

    513-636-4744
    sarah.lawson@cchmc.org

    Sarah Lawson, MD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4744

    Email: sarah.lawson@cchmc.org

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    Specialties

    Turner syndrome; endocrine disease related to oncologic pathology and treatment; septo-optic dysplasia.

    Biography

    Sarah Lawson, MD, is an assistant professor of pediatrics in the Division of Endocrinology. Her research has focused on identifying vascular changes, through non-invasive techniques, in the young Turner Syndrome population. This has been possible through the collaboration of Pediatric Endocrinology and Pediatric Cardiology.

    Dr. Lawson completed her undergraduate studies in biochemistry and biology with a minor in bible studies from Lee University, and received her MD from the University of Kentucky. After completion of her pediatric residency at the University of Kentucky, Dr. Lawson began her fellowship in pediatric endocrinology at Cincinnati Children’s Hospital Medical Center.

    Dr. Lawson’s clinical interests are in the areas of Turner syndrome, endocrine disease related to oncologic pathology and treatment, and septo-optic dysplasia.

    Education and Training

    BS: Lee University, Cleveland, TN, 2000.

    MD: University of Kentucky, Lexington, KY, 2005.

    Residency: Kentucky Children’s Hospital, Lexington, KY, 2005-2008.

    Fellowship: Cincinnati Children’s Hospital, Cincinnati, OH.

    A photo of Takahisa Nakamura.

    Takahisa Nakamura, PhD

    Research goal is to address questions concerning why and how inflammatory responses are initiated, coordinated, and thus involved in the development of obesity-induced metabolic diseases.

    513-636-4744
    takahisa.nakamura@cchmc.org

    Takahisa Nakamura, PhD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4744

    Email: takahisa.nakamura@cchmc.org

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    Specialties

    RNA-related inflammation in obesity and metabolic diseases 

    Biography

    Dr. Nakamura received his PhD from the University of Tokyo in 2003. He completed postdoctoral training in the laboratory of Dr. Gökhan S. Hotamisligil at Harvard School of Public Health in 2013, followed by his faculty appointment at Cincinnati Children's Hospital in 2013.

    Education and Training

    PhD: University of Tokyo, 2003.

    Postdoctoral Fellow: University of Tokyo, 2003-2006

    Research Fellow: Harvard University, 2006-2010

    Research Associate: Harvard University, 2010-2013

    Publications

    View PubMed Publications

    Grants

    Functional analysis of PKR, JNK, and RISC in metabolic inflammation and homeostasis. Principal Investigator. American Heart Association, Scientist Development Grant. Jan 2012 – Dec 2014.

    Analysis of pathogenic double-stranded RNA in chronic inflammatory diseases. Principal Investigator. Japan Science and Technology Agency, PRESTO. Feb 2013 – Mar 2016.
    A photo of Susan Rose.

    Susan R. Rose, MD

    investigates hypothalamic pituitary function and disorders of growth, puberty or thyroid hormone. She has special interest in the effects of neural injury on hypothalamic-pituitary function, such as after traumatic brain injury, cranial radiation, anoxia, iron overload.

    513-636-4744
    susan.rose@cchmc.org

    Susan R. Rose, MD

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-4744

    Email: susan.rose@cchmc.org

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    Specialties

    Clinical

    Neuro-endocrinology; hypothalamic-pituitary injury; growth disorders; puberty disorders; thyroid disorders; late effects of cancer

    Research

    Hypothalamic-pituitary function

    Biography

    Susan Rose is professor in the Division of Endocrinology at Cincinnati Children’s Hospital Medical Center and the University of Cincinnati. She has published over 100 review articles or chapters, and about 100 peer-reviewed articles. These include updating guidelines for care of congenital hypothyroidism and writing the chapter on thyroid for Fanaroff's and Avery's textbooks of neonatology. She’s served on the state newborn screening (NBS) committee in Tennessee. She is involved in long term follow up of newborn screening for CAH and congenital hypothyroidism with Region 4 and with the Federal Workgroup on NBS Standards.

    She has clinical expertise and research interests in hypothalamic pituitary function, thyroid hormone disorders, and in disorders of growth or puberty. She has a special interest in the effects of central nervous system injury on hypothalamic-pituitary function. In addition, she has expertise and experience in evaluating the endocrine conditions associated with congenital bone marrow failure syndromes such as Fanconi anemia, Blackfan Diamond anemia, and Shwachman-Diamond syndrome. In addition, she is evaluating the endocrine consequences of hypothalamic-pituitary injury, including traumatic brain injury and injury from treatments for cancer, as well as comparing the relative efficacy of several treatments for precocious puberty. In this study, she will be developing growth curves specific to Fanconi Anemia, recognizing that healthy children with FA may not grow along the typical growth pattern of other healthy children.

    Education and Training

    MD: Case Western Reserve School of Medicine, 1980.

    MEd: School Psychology, University of Dayton, 1972.

    Residency: The Cleveland Clinic, 1983.

    Fellowship: National Institutes of Health, 1986.

    Certification: Pediatrics, 1985; Pediatric Endocrinology, 1986.

    Publications

    View PubMed Publications
    A photo of Meilan Rutter, MD.

    Meilan M. Rutter, MD, FRACP

    is a member of several multidisciplinary clinical teams, including the Neuromuscular Comprehensive Care Center and the Center for Disorders of Sex Development (DSD). Related research interests involve endocrine issues in Duchenne muscular dystrophy, currently focusing on a trial of insulin-like growth factor-I (IGF-I) therapy in this population, and participation in a multicenter trial of parental attitudes from having a child with a DSD.

    513-636-4744
    meilan.rutter@cchmc.org

    Meilan M. Rutter, MD, FRACP

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4744

    Fax: 513-636-7486

    Email: meilan.rutter@cchmc.org

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    Specialties

    Clinical Interests

    Bone health and calcium metabolism; disorders of growth, puberty and sex development; endocrine function in cancer survivors; endocrine function in neuromuscular disorders

    Research Interests

    Insulin-like growth factor-1 (IGF-1) therapy in Duchenne Muscular Dystrophy

    Biography

    Meilan Rutter is board-certified in Pediatrics and Pediatric Endocrinology. She is an Assistant Professor of Pediatrics in the Division of Endocrinology, and joined the faculty of Cincinnati Children's Hospital Medical Center in 2008. Currently, Dr. Rutter is assistant director of the Pediatric Endocrinology Fellowship Program.

    Dr. Rutter received her degrees of Bachelor of Medicine and Bachelor of Surgery (MB, BCh) from the University of Wales College of Medicine. She completed her training in Pediatrics in New Zealand, and was admitted to Fellowship of the Royal Australasian College of Physicians (FRACP) in 1995. She underwent fellowship training in Pediatric Endocrinology at Cincinnati Children's. She completed further pediatric residency training to achieve American Board of Pediatrics specialty and subspecialty board certification.

    Dr. Rutter treats children and adolescents with endocrine disorders and diabetes mellitus. She serves as a consultant for the Neuromuscular Comprehensive Care Center and the Neuro-Oncology program at Cincinnati Children's. Additionally. she is a member of the Disorders of Sex Development interdisciplinary team.

    Education and Training

    MB, BCh: University of Wales College of Medicine, Cardiff, United Kingdom.

    FRACP: Royal Australasian College of Physicians, New Zealand.

    Residency: Auckland Children's Hospital and Dunedin Hospital, New Zealand; Cincinnati Children's, Cincinnati, OH.

    Fellowship: Pediatric Endocrinology, Cincinnati Children's, Cincinnati, OH.

    Certification: General Pediatrics, American Board of Pediatrics, 2002; Pediatric Endocrinology, American Board of Pediatrics, 2003; Pediatrics, Fellowship of the Royal Australasian College of Physicians, 1995.

    Publications

    View PubMed Publications
    A photo of Amy Shah.

    Amy S. Shah, MD, MS

    is a pediatric endocrinologist whose research focuses on the mechanisms that contribute to early onset cardiovascular and cerebrovascular disease in adolescents with obesity and type 2 diabetes. Dr. Shah’s laboratory work focuses on the contribution of high density lipoproteins (HDL) to protect against atherosclerosis and her clinical research utilizes uses noninvasive imaging modalities to measure the atherosclerotic burden in youth. She also sees patients in clinic with diabetes, endocrine concerns and lipid abnormalities.

    513-636-4744
    amy.shah@cchmc.org

    Amy S. Shah, MD, MS

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4744

    Fax: 513-636-7486

    Email: amy.shah@cchmc.org

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    Specialties

    Clinical

    Endocrinology; diabetes; lipid disorders

    Biography

    Amy S. Shah, MD, MS, is a board certified pediatric endocrinologist who research focuses on the risk factors that contribute to early atherosclerosis. Ongoing projects focus on understanding the role of lipids and lipoproteins to atherosclerosis and the use of non invasive imaging to assess early atherosclerosis. Dr. Shah's current research is funded by a K23 grant from the National Institutes of Health. Dr. Shah has received several prestigious awards including the International Society of Pediatric and Adolescent Diabetes Young Investigator Award.

    Education and Training

    MD: St. George’s University Medical School, Grenada, West Indies, 2004.

    Pediatric Residency: Loyola University Medical Center, Maywood, IL, 2007.

    Endocrine Fellowship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2010.

    Research Fellowship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2011.

    MS: Clinical Research, The University of Cincinnati, Cincinnati, OH, 2011.

    Certifications: The American Board of Pediatrics, Subspeciality Board in Pediatric Endocrinology.

    Publications

    View PubMed Publications

    Grants

    Understanding the Role of HDL Subspecies in Adolescents with Type 2 Diabetes. Principal Investigator. K23 Career Development Award, National Institutes of Health Heart, Lung and Blood. April 2014-March 2019.
    A photo of Peggy Stenger.

    Peggy Joyce Stenger, DO

    focuses on disorders of bone and calcium metabolism. She is a certified clinical densitometrist and conducts a specialty clinic for the evaluation and treatment of children with metabolic bone disease, including patients with hypophosphatemic rickets. She seeks to improve bone health by identifying and the etiology and factors contributing to multiple fractures in children.

    513-636-4744
    peggy.stenger@cchmc.org

    Peggy Joyce Stenger, DO

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4744

    Fax: 513-636-7486

    Email: peggy.stenger@cchmc.org

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    Specialties

    Disorders of bone and calcium metabolism; disorders of thyroid, puberty, growth; disorders of pituitary and adrenal; diabetes

    Biography

    Peggy J. Stenger, DO, is board-certified in Pediatrics and Pediatric Endocrinology. She has been in the Division of Endocrinology at Cincinnati Children’s since 1999. Prior to that she worked in the Babies Milk Fund at Norwood through the Department of General Pediatrics, Cincinnati Children’s Hospital Medical Center.

    She is an Assistant Professor of Pediatrics in the Division of Endocrinology. Her primary interest is in disorders of bone and calcium metabolism. She is a certified clinical densitometrist, especially interested in disorders of high bone mass.

    Dr. Stenger received her bachelor of science in biology from the University of Texas in Arlington, Texas. She received her residency training at the University of New Mexico Children’s Hospital in Albuquerque where she also served as Chief Resident. She obtained pediatric endocrinology fellowship training at Cincinnati Children’s Hospital Medical Center in Cincinnati, Ohio.

    Dr. Stenger has previously served in the Indian Health Service at Gallup Indian Medical Center, Gallup, New Mexico. Prior to coming to Cincinnati, she was on the clinical faculty in General Pediatrics at the University of New Mexico Children’s Hospital in Albuquerque. While there, she served on the New Mexico State Board of the American Diabetes Association. She was instrumental in organization of diabetes clinics at the University of New Mexico and worked in diabetes outreach clinics throughout the state.

    Education and Training

    BS:  University of Texas, Arlington, Texas.

    DO: Texas College of Osteopathic Medicine, Fort Worth, Texas.

    Residency: Pediatrics, Children's Hospital of New Mexico, Albuquerque, NM.

    Fellowship: Pediatric Endocrinology, Children's Hospital Medical Center, Cincinnati, OH.

    CCD:  International Society Clinical Densitometry.

    Certification: General Pediatrics, American Board of Pediatrics 1989; Pediatric Endocrinology, American Board of Pediatrics 1999; International Society Clinical Densitometry 2007.

    A photo of James Wells, PhD.

    James M. Wells, PhD Director, Basic Research, Division of Endocrinology

    researches the molecular mechanisms of endoderm organogenesis in mouse and humans. The goal of this work is to identify the molecular basis of congenital defects affecting the pancreas, liver, and biliary system and to direct the differentiation of pluripotent stem cells (PSCs) into therapeutic cells for replacement therapies, such as transplantable pancreatic beta cells for patients with type-1 diabetes.
    Visit the Wells Lab.

    513-636-8767
    james.wells@cchmc.org

    James M. Wells, PhD

    Director, Basic Research, Division of Endocrinology

    Director, Pluripotent Stem Cell Center

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-8767

    Fax: 513-636-4317

    Email: james.wells@cchmc.org

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    Specialties

    Research

    Understanding the development of the pancreas, and gastrointestinal organs; generating 3-dimensional human tissues from pluripotent stem cells and using these as human models of diabetes and digestive disease.

    For more information, please visit the Wells lab web page.

    Biography

    The focus of his teams basic research has been to identify the molecular mechanisms involved in the embryonic development of endocrine cells including pancreatic beta cells and tissues of the gastrointestinal tract. Their translational projects have focused on identifying new approaches to improve child health in several ways: 1. To identify and use embryonic pathways to generate complex, three-dimensional organ tissues from pluripotent stem cells, 2. Use these tissues to develop new in vitro human models for diabetes and digestive disease research and 3. Develop long-term, therapeutic strategies for cell and tissue-replacement therapies.

    Education and Training

    BS: Biochemistry, Molecular and Cell Biology, University of Maine, Orono, ME, 1987.

    PhD: Graduate program in Genetics, SUNY at Stony Brook, New York, 1995.

    Postdoctoral Fellow: Harvard University, Cambridge MA, 1996 - 2001. 

    Publications

    View Dr. Wells PubMed Publications.

    Grants

    Investigation of regional identity in human intestinal stem cells. Principal investigator (along with Shroyer NF, PI and Helmrath M, PI). National Institutes of Health. Sep 2014 – Aug 2019. NIH U01DK103117.

    Single Cell Dissection of Human Intestine Development. Principal Investigator. National Institutes of Health. Sep 2013 – Aug 2018. NIH 1R01DK098350.

    Control of human endocrine cell development. Contact Principal Investigator. National Institutes of Health. Apr 2012 – Mar 2017. NIH 1R01DK092456-01.

    Transcriptional Control of Placental Differentiation. Co-Investigator. National Institutes of Health. Feb 2011 – Jan 2016. NIH R01 HD065339.

    KLF5 regulation of intestinal development and stem cell homeostasis. Co-Investigator. National Institutes of Health. Aug 2011 – Jul 2015. NIH 1R01 DK092306-01.

    A photo of Nana-Hawa Yayah Jones.

    Nana-Hawa Yayah Jones, MD

    focuses on adherence in the management of type 1 diabetes and addressing barriers to care in children with chronic disease.

    513-636-4744
    nana.jones@cchmc.org

    Nana-Hawa Yayah Jones, MD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4744

    Fax: 513-636-7486

    Email: nana.jones@cchmc.org

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    Specialties

    Clinical Interests

    Diversity and cultural competence; non-adherence in the pediatric population; information technology in healthcare; medical education

    Research Interests

    Adherence in youth with type 1 diabetes 

    Biography

    Nana-Hawa Yayah Jones, MD, is a new clinical faculty in the division of pediatric endocrinology. Dr. Yayah Jones recently arrived in Cincinnati from St. Louis, Missouri where she completed both pediatric residency and endocrinology fellowship at Washington University's St. Louis Children's Hospital (SLCH). An additional year was spent at SLCH as a pediatric chief resident. During all the years of Dr. Yayah Jones's training she was active in fostering diversity among the medical trainees and in fact founded the Washington University Minority Medical Association (WUMMA), a group of medical trainees whose focus was on recruitment, retention and community service. As creator and president of WUMMA she became active in the resident and fellows diversity initiative created by the Barnes Jewish Hospital Center for Diversity and Cultural Competence. She mentored undergraduate student, medical students and residents throughout her training.

    During fellowship she fostered a special interest in children with chronic illness who are non-adherent to their medical regimen. Dr. Yayah Jone's research efforts will be geared towards the non-adherence type 1 diabetic who is often prone to recurrent hospitalizations and diabetes complications.

    Education and Training

    MD: University of Louisville School of Medicine, Louisville, KY, 2002.

    Residency: Pediatrics, Washington University, St. Louis Children’s Hospital, St. Louis, MO, 2005.

    Chief Residency: Pediatrics, Washington University, St. Louis Children’s Hospital, St. Louis, MO, 2006.

    Fellowship: Pediatrics, Washington University, St. Louis Children’s Hospital, St. Louis, MO, 2009.