• Basic Research

    The Division of Experimental Hematology and Cancer Biology at Cincinnati Children’s focuses on translating the results of our basic science research into new clinical therapies. Our basic research goal is to develop novel therapies that can have clinical application. 

    Our team includes talented researchers, research assistants, graduate assistants, postdoctoral fellows and support staff working in a number of developing programs:

  • The Stem Cell Biology Program studies the development and function of hematopoietic stem and progenitor cells. Learn how we are using state-of-the-art technology to better understand the factors that regulate the normal proliferation and differentiation of these cells and determinants of abnormal differentiation and growth in leukemia.

    Visit the Stem Cell Program page.

    Learn more about this program’s work to identify genes and pathways that underlie cancer and to develop preclinical and clinical tests based on our novel laboratory findings.

    Visit the Cancer Biology and Neural Tumors Program page.

    Learn how this program is dissecting the complex signaling networks that control cells at the molecular level and devising useful approaches to interfere with abnormal signaling activities in cancer and blood diseases.

    Visit the Signaling and Drug Discovery Program page.

    The Hematologic Malignancy Program focuses on understanding the molecular events associated with the development of leukemia, myelodysplasia and myeloproliferative syndromes. Learn about how our research could lead to more effective therapies for these conditions.

    Visit the Hematological Malignancy Program page.

    This program develops genetic approaches to treat inherited genetic diseases and cancer, use gene delivery to study disease pathophysiology, develop novel stable gene delivery vectors and study safety of permanent gene delivery into cells. Learn about how we translate this research into clinical trials.

    Visit the Hematology and Gene Therapy Program page.

    Learn more about this program’s work to understand the mechanisms by which circulating and cell-associated hemostatic factors contribute to development, vascular biology, tissue repair, hemostasis, immunity and disease.

    Visit the Hemostasis and Thrombosis Program page.