Experimental Hematology and Cancer Biology
Andreassen Lab

Andreassen Research Lab

Research in the Andreassen Laboratory at Cincinnati Children’s Hospital Medical Center focuses on DNA damage response mechanisms, including cell cycle checkpoint signaling and DNA repair by homologous recombination (HR), that maintain genome stability and thereby prevent tumorigenesis. The regulation and function of Fanconi anemia (FA) and breast cancer susceptibility (BRCA) genes/proteins is of particular interest, along with identifying FA-BRCA interacting proteins and understanding how FA-BRCA genes/proteins are affected by sequence variants. Additional related interests include applying insights into FA-BRCA genes/proteins to improve therapeutic approaches to cancer and related diseases, proton radiation biology, and how to ameliorate CRISPR-Cas9 mediated gene editing by enhancing HR-dependent repair of DSBs generated by Cas9.

Contact Us

A photo of Paul Andreassen.

For information regarding the Andreassen Lab contact:

Dr. Paul Andreassen
 Phone: 513-636-0499
Email: paul.andreassen@cchmc.org

Experimental Hematology and Cancer Biology
Office location: S7.419

 

 

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