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2011
Goyama S, Mulloy JC. Molecular pathogenesis of Core Binding Factor Leukemia: Current knowledge and Future prospects. Int J Hematol. [Epub ahead of print] May 3, 2011 .
Zuber J, Shi J, Wang E, Rappaport AR, Herrmann H, Sison EA, Magoon D, Qi J, Blatt K, Wunderlich M, Taylor MJ, Johns C, Chicas A, Mulloy JC, Kogan SC, Brown P, Valent P, Bradner JE, Lowe SW, Vakoc CR. RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature. [Epub ahead of print]. Aug 3 2011.
Ng KP, Ebrahem Q, Negrotto S, Mahfouz RZ, Link KA, Hu Z, Gu X, Advani A, Kalaycio M, Sobecks R, Sekeres M, Copelan E, Radivoyevitch T, Maciejewski J, Mulloy JC, Saunthararajah Y. Independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia. Leukemia. [Epub ahead of print]. Jun 24, 2011.
Chou FS, Mulloy JC. The thrombopoietin/MPL pathway in hematopoeisis and leukemogenesis. Journal of Cellular Biochemistry. 112(6):1491-1498, 2011.
Chou FS, Wunderlich M, Griesinger A, Mulloy JC. N-Ras(G12D) induces features of stepwise transformation in preleukemic human umbilical cord blood cultures expressing the AML1-ETO fusion gene. Blood. 2011.
2010
Wunderlich M, Chou FS, Link KA, Mizukawa B, Perry R, Carroll M, Mulloy JC. AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3. Leukemia. 24(10):1785-8. 2010.
Alvarez S, Suela J, Valencia A, Fernandez A, Wunderlich M, Agirre X, Prosper F, Martin-Subero JI, Maiques A, Acquadro F, Rodriguez-Perales S, Calasanz M, Roman-Gomez J, Siebert R, Mulloy JC, Cervera JV, Sanz MA, Esteller M, Cigudosa JC. DNA methylation profiles and their relationship with cytogenetic status in adult acute myeloid leukemia. PLoS ONE. 16;5(8). 2010.
Kamikubo Y, Zhao L, Wunderlich M, Corpora T, Hyde RK, Kundu M, Garrett-Beal L, Compton S, Huang G, Ito Y, Bushweller J, Mulloy JC, Liu PP. Accelerated leukemogenesis by truncated CBF beta-SMMHC defective in high-affinity binding with RUNX1. Cancer Cell. 17(5):455-68. 2010.
Mulloy JC. Peripheral T cell lymphoma: new model + new insight. J Exp Med. 207:911-913. 2010.
Mia S, Lia Z, Chena P, Hea C, Cao D, Elkahlounc A, Lud J, Pelloso LA, Wunderlich M, Huanga H, Luo RT, Sung M, Hea M, Neillya MB, Zeleznik-Le NJ, Thirman MJ, Mulloy JC, Liu PP, Rowley JD, Chen J. Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia. PNAS. 107(8):3710-5. 2010.
Mulloy JC, Cancelas J, Filippi MD, Guo F, Zheng Y. Rho GTPases in hematopoiesis and hemopathies. Blood. 115(5):936-47. 2010.
Link KA, Chou FS, Mulloy JC. Core binding factor at the crossroads: determining the fate of the HSC. Journal of Cellular Physiology. 222(1):50-6. Jan, 2010.
2009
2008
Mulloy JC, Wunderlich M, Zheng Y, Wei J. Transforming human blood stem and progenitor cells: a new way forward in leukemia modeling. Cell Cycle. 7(21): 57-52. 2008.
Wei J, Wunderlich M, Fox C, Alvarez S, Cigudosa JC, Wilhelm JE, Zheng Y, Cancelas JA, Gu Y, Jansen M, DiMartino JF, Mulloy JC. Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia. Cancer Cell. 13(6): 483-495. 2008.
Krejci O, Wunderlich M, Geiger H, Schleimer D, Jansen M, Andreassen PR, Mulloy JC. p53 signaling in response to increased DNA damage sensitizes AML1-ETO cells to stress-induced death. Blood. 111(4): 2190-2199. 2008.
Other Significant Publications
Wunderlich M, Krejci O, Wei J, Mulloy JC. Human CD34+ cells expressing the inv(16) fusion protein exhibit a myelomonocytic phenotype with greatly enhanced proliferative ability. Blood. 108(5)1690-1697. 2006.
Mulloy JC, Jankovic V, Wunderlich M, Delwel R, Cammenga J, Krejci O, Zhao H, Valk PJ, Lowenberg B, Nimer SD. AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34+ cells, allowing nerve growth factor-induced expansion. PNAS. 102(11):4016-21. 2005.
Mulloy JC, Cammenga J, Berguido FJ, Wu K, Zhou P, Comenzo RL, Jhanwar S, Moore MAS, Nimer SD. Maintaining the self-renewal and differentiation potential of human CD34+ hematopoietic cells using a single genetic element. Blood. 102(13)4369-4376. 2003.
Mulloy JC, Cammenga J, MacKenzie K, Moore MAS, Nimer SD. The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells. Blood. 99(1)15-23. 2002.
