• Meet the Bezerra Lab

  • Kazuhiko Bessho headshot.
    Kazuhiko Bessho headshot.

    Kazuhiko Bessho, MD, PhD

    Staff Scientist
    Dr. Bessho is interested in the molecular basis of diversity of clinical phenotype in patients with biliary atresia. Combining analyses from patients with complementary studies in an experimental model of biliary atresia, he is elucidating molecular networks associated with clinical phenotype in biliary atresia.

    Kazuhiko Bessho

    Jorge A. Bezerra headshot.
    Jorge A. Bezerra headshot.

    Jorge A. Bezerra, MD

    Pediatric Gastroenterologist, Staff Hepatologist, Director of Research, Director of the Digestive Health Center
    Dr. Jorge Bezerra investigates the genetic, cellular and molecular basis of biliary atresia and other cholangiopathies in children. He studies diseased tissues and uses complementary animal models to identify causes of liver injury and to develop new therapies to stop progression of liver disease.

    Jorge A. Bezerra

    Frank DiPaola headshot.
    Frank DiPaola headshot.

    Frank DiPaola, MD

    Clinical Fellow, Pediatric Gastroenterology
    Dr. Dipaola is investigating the cellular phenotype of peribiliary glands and the role of peribiliary glands in the setting of duct injury in biliary atresia.

    Frank DiPaola

    Jun Li headshot.
    Jun Li headshot.

    Jun Li, PhD

    Research Fellow
    Dr. Li investigates the role of CD4+ T cells in the pathogenesis of biliary atresia. Her research focuses on the interplay among cytokines, transcription factors and innate cells during activation, differentiation, and expansion of CD4+ T cells in disease pathogenesis.

    Jun Li

    Reena Mourya headshot.
    Reena Mourya headshot.

    Reena Mourya, Mpharm

    Research Assistant IV
    Reena explores several high-throughput multi-gene sequencing technologies to discover genetic mutations in children with inherited syndromes of intrahepatic cholestasis. She also studies molecular and inflammatory signatures categorizing heterogeneous populations of patients with biliary atresia.

    Reena Mourya

    Janet Pfister headshot.
    Janet Pfister headshot headshot.

    Janet Pfister

    Research Assistant II
    Janet is investigating the role of complement cascade in the pathogenesis of biliary atresia. Using a mouse model, she is conducting a series of experiments to determine the role of iC3b, C5b-9 and complement receptors C3aR and C5aR in bile duct epithelial injury and obstruction.

    Janet Pfister

    Rachel Sheridan headshot.
    Rachel Sheridan headshot.

    Rachel Sheridan, MD

    Clinical Fellow
    Dr. Sheridan’s research focuses on the molecular and cellular basis of hepatobiliary injury in human and experimental models of liver and biliary disease, with special interest in the pathogenesis of biliary atresia.

    Rachel Sheridan

    Pranav Shivakumar headshot.
    Pranav Shivakumar headshot.

    Pranav Shivakumar, PhD

    Instructor of Pediatrics
    Dr. Shivakumar is investigating the mechanistic role of innate immunity in the pathogenesis of biliary atresia focusing on NK- and T-cells and complement components in the initiation and propagation of inflammatory duct injury and obstruction.

    Pranav Shivakumar

    Stephanie Walters headshot.
    Stephanie Walters headshot.

    Stephanie Walters, MS

    Research Assistant III
    Stephanie is investigating the role of small molecules and ligands in the pathogenesis of Biliary Atresia. Using a mouse model and in vitro systems, she is conducting a series of experiments to effectors of bile duct epithelial injury and obstruction.
    Bachelors of Science, Ohio State University, Ohio, 2008
    Masters of Science, University of Cincinnati, Ohio, 2010

    Stephanie Walters

  • Bezerra Lab group shot.

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