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We are investigating hepatic vascular morphogenesis and the interdependence of the vascular-biliary systems.
We are investigating hepatic injury response and its effects on the physiological communicating biliary architecture.
We are investigating cholangiocyte (i.e., bile duct epithelial cell) heterogeneity.
We are performing an unbiased high-throughput biochemical screen to identify lead compounds that target the stability of the Notch intracellular domain (NICD).