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Sean Moore’s long-term goal is to understand and reverse the vicious cycle of undernutrition and infection among children in developing countries. Ongoing research efforts include:
Since July 2013, Russell E. Ware, MD, PhD, and his team have launched three international sickle cell disease initiatives to promote the diagnosis, care and treatment of children with sickle cell who live in sub-Saharan Africa, an area hardest hit by the disease.
Mark Steinhoff, MD, director of the Global Health Center at Cincinnati Children’s, and his international team of seven coauthors have been recognized for advancing the case for influenza immunization during pregnancy.
The group published an article, titled “Neonatal outcomes after influenza immunization during pregnancy: a randomized controlled trial,” in CMAJ, a journal of the Canadian Medical Association (CMAJ 2012;184:645-53).
In recognition of their work, they recently received the Bruce Squires Award. This award is given annually to the author(s) of the research paper published in the journal that is most relevant to the practice of medicine and most likely to impact it in a positive way.
The study, conducted in Bangladesh, offers the first evidence that maternal immunization during pregnancy is associated with fewer babies born who are small for their gestational age and an increase of the average birth weight by 200 grams.
“That was a completely new finding,” says Steinhoff. “The vaccine clearly showed a difference in birth weight, indicating that maternal immunization benefited the fetus.”
All of the women in the study were in their third trimester, when fetal growth is at its peak. If the mother becomes ill and is unable to eat, it can make a big difference, says Steinhoff.
Subsequent studies conducted by other researchers in the United States and Canada have showed similar results.
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