Ambroggio Lab

  • Ambroggio Lab Research

    The goal of the Ambroggio lab is to improve the health of children through improved diagnostic methods for common serious infections. The specific focus of the lab is to improve the care of children with pneumonia by developing better detection methods for pathogen etiology and more sensitive imaging techniques to detect pneumonia. This will allow clinicians to more accurately prescribe effective pharmacotherapy.

    We are pursuing these goals through research in ultrasonography and metabolomics which will permit the identification of candidate biomarkers that can ultimately be translated to the bedside for rapid pathogen identification.

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    Publications

    Thomson JE, Ambroggio L, Murtagh Kuroski E, Statile AM, Iyer S, White C, Shah SS. Resource utilization associated with guideline recommended antibiotic therapy for community acquired pneumonia. (Under Review)

    Ambroggio L, Test M, Metlay JP, Graf TR, Blosky MA, Macaluso M, Shah SS. Adjunct Systemic Corticosteroid Therapy in Children with Community-Acquired Pneumonia in the Outpatient Setting. Journal of the Pediatric Infectious Diseases Society. (In Press)

    Test M, Ambroggio L, Metlay JP, Graf TR, Blosky MA, Macaluso M, Shah SS. Beta-lactam versus beta-lactam/macrolide therapy in pediatric outpatient pneumonia. (Under Revision)

    Test M, Shah SS, Monuteaux M, Ambroggio L, Lee EY, Markowitz RI, Bixby S, Diperna S, Servaes S, Hellinger JC, Newman MI (2013) Impact of Clinical History on Chest Radiograph Interpretation. Journal of Hospital Medicine. 8 (7): 359-364

    Ambroggio L, Thomson J, Murtagh-Kurwoski E, Courter J, Statile A, Graham C, Iyer S, Shah SS, White C. (2012) Quality Improvement Methods to Increase Appropriate Antibiotic Prescribing for Childhood Community-Acquired Pneumonia. Pediatrics 131 (5) e1623-1631

    Ambroggio L, Taylor JA, Tabb LP, Newschaffer CJ, Evans AA, Shah SS. (2012) Comparative Effectiveness of Beta-lactam Monotherapy and Beta-lactam-macrolide Combination Therapy in Children Hospitalized with Community Acquired Pneumonia. Journal of Pediatrics. 161 (6): 1097-1103.

    Ambroggio L, Tabb LP, O’Meara T, Sheffler-Collins S, McGowan KL, Shah SS. (2012) Antibiotic Susceptibility Patterns Influence on Empiric Antibiotic Prescribing for Children Hospitalized with Community Acquired Pneumonia. Pediatric Infectious Diseases Journal. 31 (4): 331-336.

    Ambroggio, L., Lorch, S.A., Mohamad, Z., Mossey, J., Shah, S.S. (2009). Congenital Anomalies and Resource Utilization in Neonates Infected with Herpes Simplex Virus. Sexually Transmitted Diseases. 36 (11): 680-685.

    Peer-Reviewed Commentaries

    Ambroggio L, Shah SS. (2013) Invited Commentary: Administrative Data: Expanding the Infrastructure for Pediatric Research. Journal of Pediatrics.162 (4): 681-684.

    Ambroggio L, Smith, MJ, Shah SS. (2012) Invited Commentary: Quasi-Experimental and Interrupted Time Series Design. Journal of Pediatric Infectious Diseases Society. : 1-3.