• Research Faculty

  • A photo of Robert W. Frenck Jr.

    Robert W. Frenck Jr., MD Interim Director, Division of Infectious Diseases

    has been working on the clinical testing of the 13-valent conjugate pneumococcal vaccine. Current trials include use of the vaccine in children who have undergone bone marrow transplant. He also developed evaluation of a model for norovirus infection, and will be leading a series of clinical trials to test a new candidate vaccine to prevent infections by Shigella.


    A photo of David Bernstein.

    David I. Bernstein, MD, MA Director, Gamble Program and VTEU

    conducts clinical vaccine trials, including trials involving infants and the elderly that are supported by the NIH through the Vaccine and Treatment Evaluation Unit which he directs at Cincinnati Children’s. His special interest is the pathogenesis and immunobiology of herpes viruses (herpes simplex and cytomegalovirus). 


    No photo available

    Steven Black, MD

    is focusing on the evaluation of vaccine safety, vaccine efficacy and the epidemiology of vaccine preventable diseases in the United States but especially in the developing world. He is interested in fostering collaborative efforts to improve vaccine safety and effectiveness assessment in low and middle income countries.


    A photo of Rebecca Brady.

    Rebecca C. Brady, MD Director, Adult Clinical Services

    is interested in adult vaccines and influenza. Dr. Brady is the PI for funded clinical trials of influenza vaccines in children and adults.


    A photo of Rhonda Cardin.

    Rhonda Cardin, PhD

    studies the viral/host interactions that contribute to cytomegalovirus (CMV) pathogenesis and latency. Her lab recently identified the first CMV gene, M33, that plays a critical role in CMV latency. Her current studies aim to identify the mechanisms of M33 function in latency and may lead to therapies to control long-term latent CMV infection.


    A photo of Beverly Connelly.

    Beverly L. Connelly, MD Director, Infection Control Program

    is interested in the epidemiology of vaccine-preventable diseases with a particular focus on influenza and pertussis. She is also interested in the epidemiology and prevention of healthcare-associated infections with a focus on device-related infections. In addition, she is interested in healthcare quality improvement initiatives.


    A photo of Lara Danziger-Isakov.

    Lara A. Danziger-Isakov, MD, MPH Director, Transplant ID

    is a clinician and clinical researcher focusing on infections in immunocompromised hosts, primarily transplant recipients. She studies the interactions among infection, immunity and graft outcomes in pediatric transplantation. Additionally, Dr. Danziger-Isakov studies immunizations and infectious disease risk assessment in pediatric solid organ transplantation.


    A photo of Michelle Dickey.

    Michelle P. Dickey, MS, APRN, CFNP, CPNP, CCRC Nurse Practitioner

    has interests in the area of clinical vaccine trials in infants, children, adolescents, adults, elderly, pregnant and breastfeeding populations. Additional interests in clinical research include the areas of informed consent and quality management. With collaborators, Ms. Dickey has undertaken an innovative approach to simplified informed consent and assent.

    A photo of David Hartley.

    David M. Hartley, PhD, MPH

    investigates the factors governing the emergence and transmission of infectious diseases by applying mathematical modeling and computer simulation methods. He is also interested in data analytic and information technology approaches for understanding and improving communications in healthcare settings and improving patient safety.


    A photo of David Haslam.

    David B. Haslam, MD Director, Antimicrobial Stewardship Program

    is a pediatric infectious diseases physician who has research programs investigating the host and microbial factors that contribute to disease severity and outcome during Clostridium difficile infection. As medical director of the Antimicrobial Stewardship Program, he is initiating additional research programs on the interplay between antibiotic exposure, the host microbiome, and the molecular epidemiology of antimicrobial resistance.


    A photo of Andrew Herr.

    Andrew B. Herr, PhD

    studies protein-protein interactions involved in immune receptor signaling and bacterial pathogenesis. His lab uses X-ray crystallography to solve the atomic structures of proteins along with techniques of biophysical chemistry to understand their interactions in solution. The goal is to understand the molecular basis for autoimmune responses and recurrent bacterial infections, and to develop new therapeutic applications.
    Visit the Herr Lab.


    A photo of Margaret Hostetter.

    Margaret K. Hostetter, MD BK Rachford Professor and Chair, Department of Pediatrics

    studies the pathogenesis of bloodstream infections caused by the yeast Candida albicans. Her work has highlighted the role of C. albicans in biofilms, activation of human T cells, and evasion of innate immune mechanisms. Her clinical research is focused on the medical evaluation of internationally adopted children.


    A photo of Xi Jason Jiang.

    Xi Jason Jiang, PhD

    focuses on enteric viruses causing acute gastroenteritis, mainly the human noroviruses and rotaviruses. His major approaches include molecular virology, recombinant technology, epidemiology, immunology and bioinformatics. He is also interested in development of vaccine and antivirals against these important pathogens.


    A photo of Monica McNeal.

    Monica Malone McNeal, MS Associate Director, Laboratory of Specialized Clinical Studies

    directs the Laboratory for Specialized Clinical Studies, which develops and performs state-of-the-art assays for assessment of viruses and human immune responses.


    A photo of Grant Paulsen.

    Grant C. Paulsen, MD

    conducts clinical research complementary to his clinical role focusing on infectious complications in immune compromised hosts. Dr. Paulsen explores issues related to vaccination in the post-transplant setting, management of viral infections in immune compromised hosts and the impact of pre-transplant infectious disease evaluation.


    A photo of Joseph Qualls.

    Joseph E. Qualls, PhD

    examines the cellular and molecular facets of macrophage biology during health and disease. This white blood cell has an unprecedented role in regulating inflammation, pathogen elimination and maintaining tissue homeostasis. Specifically, Dr. Qualls’ laboratory focuses on amino acid utilization by macrophages, and how this affects the outcome of infection and inflammatory disease.


    A photo Nancy M. Sawtell.

    Nancy M. Sawtell, PhD

    leads studies of herpes simplex virus and has identified VP16, the first gene essential for triggering the virus’s emergence from its latent state in the human nervous system. Reactivation of the virus in the brains of older mice carrying the human APOE 4 gene to leads to lesions that resemble Alzheimer’s.
    Visit the Sawtell Lab.


    A photo of Elizabeth Schlaudecker.

    Elizabeth P. Schlaudecker, MD, MPH

    uses epidemiology and clinical studies to explore the interplay between maternal and child immunologic responses to immunization. Past studies on respiratory viruses in Honduras have led to her current focus on immunologic responses to influenza. Her primary research goal is to improve the prevention of pediatric infectious diseases worldwide.


    A photo of Mary Staat.

    Mary Allen Staat, MD, MPH Director, International Adoption Center

    is interested in population-based epidemiological surveillance studies in order to understand what viral and bacterial diseases are circulating at any given time, as well as to evaluate the efficacy of vaccines for these agents. She has also been a leader in the medical and psychological evaluation of internationally adopted children.


    A photo of Mark Steinhoff.

    Mark C. Steinhoff, MD Director, Global Health Center

    is interested in the broad effects of immunization in prevention of illness both in US and low-resource regions. The Mother’s Gift project of antenatal maternal immunization with influenza vaccine showed protection of mothers and their unvaccinated infants, as well as increased birth weights of the newborns. His team is currently evaluating antenatal influenza vaccine in 3,600 pregnant women in S. Asia to assess the broader effects of prevention of influenza. In Cincinnati, they are evaluating the safety and immunogenicity of influenza vaccines provided to mothers after delivery. They are also carrying out a prospective antepartum influenza vaccine study to assess the differences in immune response between healthy pregnant and nonpregnant women.


    A photo of Ming Tan.

    Ming Tan, PhD

    is interested in understanding the initial steps of human norovirus infection and in developing strategies to prevent the infection. His research focuses on the structure-function relationship of norovirus capsid to understand how norovirus interacts with host cells through the viral receptors that have recently been identified as human histo-blood group antigens.


    A photo of Sing Sing Way.

    Sing Sing Way, MD, PhD Pauline and Lawson Reed Chair, Division of Infectious Diseases

    is an infectious disease physician-scientist. He cares for infants and children with infection related illness, and provides consultation in the diagnosis and prevention diseases caused by communicable agents. Dr. Way supervises an active basic research laboratory that uses basic immunological approaches to investigate ways to boost host defense and protection against infection. If you have interest in this work, please contact Dr. Way.