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Research Assistant III
Ashley joined our lab in 2007 as a student in the Molecular and Developmental Biology Graduate Program at the University of Cincinnati. Her research focuses on the early role of Zic3 in processes such as left-right and axial patterning. Additionally, she is exploring the interaction of Zic3 with various signaling pathways that are important for directing early development in both patterning and morphogenesis.
Jason is a graduate student in the Molecular and Developmental Biology Program at the University of Cincinnati. He joined the lab in 2009 after several years working as a genetic counselor/research coordinator. His research uses Xenopus tropicalis as a model organism for functional assessment of copy number variants (CNVs) detected in patients with heterotaxy syndrome.
Research Assistant IV
Since joining the Ware Lab in 2007, Allison has studied heart development in heterotaxy mouse models. She is investigating the cause of congenital heart defects resulting from Zic3 deficiency to determine whether these defects are caused directly by Zic3 loss of function or by earlier left-right patterning abnormalities.
Nicole became part of the Ware Lab in September of 2009. She manages basic supply ordering, meeting coordination and other essential business functions in the lab.
Malgorzata is studying how Zic3 interacts with other transcription factors in regulation of gene expression. She is working on investigating developing limb buds, since this is where the Shh pathway and the role of Gli3 have been particularly well described, and where Zic3 is also expressed.
Mardi enrolled in the Molecular and Developmental Biology graduate program at the University of Cincinnati in 2008, shortly before she joined our lab. She aims to understand the role of Zic3 in left-right patterning and its effect on heart development using mouse models.
Postdoctoral Research Fellow
Tariq joined the Ware lab in 2009. He is interested in the development of novel genetic diagnostics for cardiomyopathy patients using long-range PCR and custom non-PCR based sequencing methods. His second research area involves identification of novel genetic causes of congenital heart disease/heterotaxy through copy number variation (CNV) analysis.
Dr. Ware is a clinical geneticist who has basic and translational research programs in cardiac structure and function. Her lab studies the genetic and developmental basis of congenital heart defects, with specific interest in the molecular mechanisms controlling heart sidedness in developmental diseases such as X-linked heterotaxy. Translational research in pediatric cardiomyopathy is a second lab focus.
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