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Sengupta, A. V.V. Kalinichenko, K.E. Yutzey. FoxO and FoxM1 transcription factors have antagonistic functions in neonatal cardiomyocyte cell cycle withdrawal and IGF1 gene regulation. Circ. Res. 112:267-277. 2013.
Carruthers, C.A., C.M. Alfieri, E.M. Joyce, S.C. Watkins, K.E. Yutzey, M.S. Sacks.Gene expression and collagen fiber micromechanical interactions of the semilunar heart valve interstitial cell. Cell. Mol. Bioeng. 5:254-265.
Mead TJ, Yutzey KE.Notch pathway regulation of neural crest cell development in vivo.Dev. Dyn. 2012:241:376-389.
Chakraborty S, Yutzey KE.Tbx20 regulation of cardiac cell proliferation and lineage specialization during embryonic and fetal development in vivo.Dev. Biol. 2012:363:234-246.
Cheek JD, Wirrig EE, Alfieri CM, James JF, Yutzey KE. Differential activation of alvulogenic, chondrogenic and osteogenic pathways in mouse models of myxomatous and calcific aortic valve disease. J. Mol. Cell. Cardiol. 2012:52:689-700.
Le TT, Conley KW, Mead TJ, Rowan S, Yutzey KE, Brown NL. Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development. Dev. Dyn. 2012:241:493-504.
Sengupta A, Chakraborty S, Paik J, Yutzey KE, and Evans-Anderson HJ. FoxO1 is required in endothelial but not myocardial cell lineages during cardiovascular development.Dev. Dyn. 2012:241:803-813.
Fujimoto KL, Tobita K, Guan J, Hashizume R, Takanari K, Alfieri CM, Yutzey KE, Wagner WR. Placement of an elastic biodegradable cardiac patch on a subacute infarcted heart leads to cellularization with early developmental cardiomyocyte characteristics.J. Card. Fail. 2012:18:585-595.
Braitsch CM, Combs MD, Quaggin SE, Yutzey KE Pod1/Tcf21 is regulated by retinoic acid signaling and inhibits differentiation of epicardium derived cells into smooth muscle in the developing heart. Dev. Biol. 2012:368:345-357.
Hinton RB,Yutzey KE. Heart valve structure and function in development and disease. Ann Rev. Physiol. 2011:73:29-36.
Lincoln J, Yutzey KE. Molecular and developmental mechanisms of congenital heart valve disease. Birth Defects Res Part A: Clin. Mol. Teratol. 2011:91:526-534.
Combs MD, Braitsch CM, Lange AW, James JF, Yutzey KE. NFATc1 promotes epicardium-derived cell (EPDC) invasion into myocardium. Development 2011:138:1747-1757.
Lee MP and Yutzey KE. Twist1 directly regulates genes that promote cell proliferation and migration in developing heart valves. PLoS One 2011:6:e29758.
Wirrig EE, Hinton RB, Yutzey KE. Differential expression of cartilage and bone-related proteins in pediatric and adult diseased heart valves. J. Mol. Cell. Cardiol. 2011:50:561-569.
Sengupta A, Molkentin JD, Paik JH, DePinho RA, Yutzey KE. FoxO transcription factors promote cardiomyocyte survival upon induction of oxidative stress. J. Biol. Chem. 2011:286:7468-7478.
Wirrig EE, Yutzey KE. Transcriptional regulation of heart valve development and disease. Invited Review. Cardiovasc. Pathol. 20:162-167. 2011.
Wirrig EE, Hinton RB, Yutzey KE. Differential expression of cartilage and bone-related proteins in pediatric and adult diseased heart valves. J. Mol. Cell. Cardiol. 50:561-569. 2011.
Sengupta A, Molkentin JD, Paik JH, DePinho RA, Yutzey KE. FoxO transcription factors promote cardiomyocyte survival upon induction of oxidative stress. J. Biol. Chem. 286:7468-7478. 2011.
Hinton RB, Yutzey KE. Heart valve structure and function in development and disease. Invited Review. Ann Rev. Physiol. 73:29-36. 2011.
Lincoln J, Yutzey KE. Molecular and developmental mechanisms of congenital heart valve disease. Birth Defects Res Part A: Clin. Mol. Teratol. 91:526-534. 2011.
Combs MD, Braitsch CM, Lange AW, James JF, Yutzey KE. NFATc1 promotes epicardium-derived cell (EPDC) invasion into myocardium. Development. 138:1747-1757. 2011.
Chakraborty S, Wirrig EE, Hinton RB, Merrill WH, Spicer DB, Yutzey KE. Twist1 promotes heart valve cell proliferation and extracellular matrix gene expression during development in vivo and is expressed in human diseased aortic valves. Dev. Biol. 347: 167-179. 2010.
Alfieri CM, Cheek J, Chakraborty S, Yutzey KE. Wnt signaling in heart valve development and osteogenic gene induction. Dev. Biol. 338:127-135. 2010.
Yutzey KE. DiGeorge syndrome, Tbx1, and retinoic acid signaling come full circle. Circ. Res. 106:630-632. 2010.
Chakraborty S, Combs MD, Yutzey KE. Transcriptional regulation of heart valve progenitor cells. Ped. Cardiol. 31:414-421. 2010.
Wirrig EE, Yutzey KE. Transcriptional regulation of heart valve development and disease. Cardiovasc. Pathol. 2010.
Mead TJ, Yutzey KE. Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development. Proc. Natl. Acad. Sci. USA. 106:14420-14425. 2009.
Combs MD, Yutzey KE. Heart valve development: regulatory networks in development and disease. Circ. Res. 105:408-421. 2009.
Combs MD, Yutzey KE. VEGF and RANKL regulation of NFATc1 in heart valve development. Circ. Res. 105:565-574. 2009.
Sengupta A, Molkentin JD, Yutzey KE. FoxO transcription factors promote autophagy in cardiomyocytes. J. Biol. Chem. 284:28319-28331. 2009.
Evans-Anderson HJ, Alfieri CM, Yutzey KE. Regulation of cardiomyocyte proliferation and myocardial growth during development by FOXO transcription factors. Circ. Res. 102:686-694. 2008.
Shelton EL, Yutzey KE. Twist1 function in endocardial cushion cell proliferation, migration, and differentiation during heart valve development. Dev. Biol. 317:282-295. 2008.
Yutzey KE. Teed off: Cardiac conduction system development requires T-box transcription factors. Circ. Res. 102:1295-1297. 2008.
Hinton RB, Alfieri C, Witt S, Glascock B, Khoury PR, Benson DW, Yutzey KE. Mouse Heart Valve Structure and Function: Echocardiographic and Morphometric Analyses from the Fetus through the Aged Adult. Am. J. Physiol. – Heart and Circ. Physiol. 480-2488. 2008.
Chakraborty S, Cheek J, Sakthivel B, Aronow BJ, Yutzey KE. Shared gene expression profiles in developing heart valves and osteoblasts. Physiol. Genomics. 35:75-85. 2008.
Boni A, Urbanek K, Nascimbene A, Hosoda T, Zheng H, Delucchi F, Amano K, Gonzalez A, Vitale S, Ojaimi C, Rizzi R, Bolli R, Yutzey KE, Rota M, Kajstura J, Anversa P, Leri A. Notch1 regulates the fate of cardiac progenitor cells. Proc. Natl. Acad. Sci. USA. 105:15529-15534. 2008.
Shelton EL, Yutzey KE. Tbx20 regulation of endocardial cushion cell proliferation and extracellular matrix gene expression. Dev. Biol. 302:376-388. 2007.
Yutzey KE, Robbins J. Principles of genetic murine models for cardiac disease. Circulation 115:792-799. 2007.
Alfieri CM, Evans-Anderson HJ, Yutzey KE. Developmental regulation of the mouse IGF-I exon 1 promoter region by calcineurin activation of NFAT in skeletal muscle. Am. J. Physiol. Cell Physiol. 292:C1887-1894. 2007.
Lincoln J, Kist R, Scherer G, Yutzey KE. Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development. Dev. Biol. 305:120-132. 2007.
Lincoln J, Alfieri CM, Yutzey KE. BMP and FGF regulatory pathways control cell lineage diversification of heart valve precursor cells. Dev. Biol. 292:290-302. 2006.
Lange AW, Yutzey KE. NFATc1 expression in the developing heart valves is responsive to the RANKL pathway and is required for endocardial expression of cathepsin K. Dev. Biol. 292:407-417. 2006.
Lincoln J, Lange AW, Yutzey KE. Hearts and bones: shared regulatory mechanisms in heart valve, cartilage, tendon, and bone development. Dev. Biol. 294:292-302. 2006.
Hinton RB, Lincoln J, Deutsch GH, Osinska H, Manning PB, Benson DW, Yutzey KE. Extracellular matrix remodeling and organization in developing and diseased aortic valves. Circ Res. 98:1431-1438. 2006.
Lange AW, Rothermel BA, Yutzey KE. Restoration of DSCR1 to disomy in trisomy 16 mouse model of Down syndrome does not correct cardiac or craniofacial development anomalies. Dev. Dyn. 233:954-963. 2005.
Lange AW, Molkentin JD, Yutzey KE. DSCR1 gene expression is dependent on NFATc1 during cardiac valve formation and colocalizes with anomalous organ development in trisomy 16 mice. Dev. Biol. 266:346-360. 2004.
Lincoln J, Alfieri CM, Yutzey KE. Development of heart valve leaflets and supporting apparatus in chicken and mouse embryos. Dev Dyn. 230: 239-250. 2004.
Plageman TF, Yutzey KE. Differential expression and function of Tbx5 and Tbx20 in cardiac development. J. Biol. Chem. 279: 19026-19034. 2004.
Bushdid PB, Osinska H, Waclaw RR, Molkentin JD, Yutzey KE. NFATc3 and NFATc4 are required for cardiac development and mitochondrial function. Circ. Res. 92:1305-1313. 2003.
Katherine Yutzey, PhD
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