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Melinda performed her graduate studies at the University of Kansas Medical Center in Anatomy & Cell biology with an emphasis in neuroscience in 2007. Prior to coming to Cincinnati Children’s, she was a postdoctoral fellow at Vanderbilt University Medical Center. Her research interests are centered on experience-based epigenetic regulation of gene function, specifically methylation of the amygdalar glucocorticoid receptor as a result of early life experience.
Katherine obtained her Bachelors degree from Xavier University in 2011. Currently a graduate student in the lab, Katherine is working to further the understanding of the molecular mechanisms regulating parturition. Her project focuses on the function of Inverted Formin-2 (INF2) in pregnancy and how its dysregulation may contribute to preterm birth.
received her bachelor’s degree from Indiana University Bloomington in
2011. She is a student in the Medical Scientist Training Program (MD/PhD)
at the University of Cincinnati. Her project focuses on
corticotropin-releasing hormone (CRH), a placental hormone associated with
birth timing. She is interested in the evolution and regulation of CRH
expression by endogenous retroviral elements.
Gloria received her Bachelors degree from the University of Maryland Eastern Shore in 2008. Gloria is currently a graduate student in the lab working on understanding the molecular mechanisms through which stress leads to psychiatric disorders. Her project focuses on site-specific overexpression of corticotropin-releasing hormone (CRH) in amygdalar nuclei in mice to evaluate the impact of CRH dysregulation on stress-related behaviors.
Candice obtained her
Bachelors degree in biochemistry at Seattle Pacific University in 2005. She completed medical school and pediatric residency at the University of
Michigan in Ann Arbor, MI. She is currently a clinical fellow in
neonatalogy at Cincinnati Children's. Her primary project involves investigation of the genetic influences on
preterm birth through genome wide association studies and whole exome
sequencing. She is also involved in recruitment, interviewing, and sample
collection for the FETAL (Family and Environment in Timing for Abnormal Labor)
study. Finally, she is involved with epidemiologic work examining the
influences of pre-pregnancy BMI, pregnancy weight gain, and interpregnancy
interval on premature birth.
Lisa obtained her PhD in Pathology from the University of Chicago. She is working on a project to understand the neural pathways signaling stress effects through the glucocorticoid receptor. Dysregulation of the stress response can result in psychiatric disease. Lisa is currently analyzing how “knocking-out” glucocorticoid receptor in the amygdala alters downstream signaling pathways.
Amrita obtained her MS in Chemistry from the Calcutta University, India and joined the Muglia lab group in January 2012. Amrita has been involved in pluripotent stem cell research in the cardiac system has also investigated role of degeneration and regeneration of peripheral nervous system post injury. She will use her expertise to explore the role of signaling pathways related to preterm birth and stress responses.
Xuzhe is a graduate student in the Molecular and Developmental Biology Graduate Program, a native of China, studying the role of novel placental genes unique to mammals for their role in control of the timing for birth.
Click image for caption.
Left to Right- Melinda Arnett, Louis Muglia, Amrita Mukherjee, Lisa Muglia, Gloria Laryea
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